Healthcare · Biotechnology
Price
$3.94
Market Cap
$8.6M
Employees
37
Beta
1.67
Avg Volume
32,832
CEO
Jeffrey G. Lamothe
Aptevo Therapeutics Inc. is a clinical-stage biotechnology company primarily focused on pioneering immunotherapeutic agents for a variety of cancer treatments across the United States. Its foremost investigational drug, APVO436, is a bispecific antibody crafted to engage T-cells, which is currently undergoing a Phase 1b clinical study for acute myeloid leukemia and myelodysplastic syndromes. Beyond its lead asset, Aptevo's research pipeline encompasses several preclinical compounds. These include ALG.APV-527, an experimental bispecific ADAPTIR molecule designed to target both 4-1BB (CD137) and 5T4, a tumor-specific antigen prevalent in numerous cancer types. Another promising candidate is APVO603, a dual agonist bispecific antibody that targets both 4-1BB and OX40. The company is also advancing APVO442, a bispecific agent leveraging its ADAPTIR-FLEX platform technology to improve the precise delivery of drugs to prostate-specific membrane antigen (PSMA)-positive tumors for the treatment of prostate cancer. To further its development efforts for ALG.APV-527, Aptevo maintains a collaborative partnership and option agreement with Alligator Bioscience AB. Founded in 2016, Aptevo Therapeutics Inc. operates from its headquarters located in Seattle, Washington.
Runs with full report
Price Overview
Last updated: Jul 10, 2026 4:17am (just now)
Current data · timestamped when a report runs
$3.94
Change · Jul 10
-0.56 (-12.44%)
Day Range
$3.80 – $4.00
52-Week Range
$3.72 – $59.40
50-Day MA
$4.79
200-Day MA
$12.46
Volume
159,098.00
Share Structure
Outstanding
1,246,104.00
Float
1,146,836.00
Free Float
92.0%
High free float
— 92.0% of shares trade freely, ~8% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Small absolute float (1.1M shares) — even with a decent free float %, volume can be thin. Check average daily volume before sizing a position.
Price History (1 Year)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
API Direct from provider
CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALCStock Price / EPS (Diluted)
-0.05
Stock Price: $3.94
EPS (Diluted): -87.27
EPS (Diluted): -87.27
P/B Ratio (Price vs net asset value)
APIStock Price / Book Value Per Share
0.00
Stock Price: $3.94
Total Equity: $17.38M
Shares: 3,155
Total Equity: $17.38M
Shares: 3,155
EV/EBITDA (Total value vs operating profit)
APIEnterprise Value / EBITDA
0.06
Market Cap: $8.62M
Total Debt: $866,000
Cash: $21.62M
EBITDA: -$25.73M
Total Debt: $866,000
Cash: $21.62M
EBITDA: -$25.73M
Enterprise Value (Takeover price (cap + debt - cash))
APIMarket Cap + Total Debt - Cash
-$16.9M
Market Cap: $8.62M
Total Debt: $866,000
Cash: $21.62M
Total Debt: $866,000
Cash: $21.62M
P/S Ratio (Price per dollar of revenue)
APIStock Price / Revenue Per Share
0.00
Stock Price: $3.94
Revenue: $0.00
Shares: 3,155
Revenue: $0.00
Shares: 3,155
EV/Sales (Total value vs revenue — works when P/E can't)
API0.00
Gross Margin (Revenue left after direct costs)
APIGross Profit / Revenue
0.0%
Gross Profit: -$240,000
Revenue: $0.00
Revenue: $0.00
Operating Margin (Revenue left after all operations)
APIOperating Income / Revenue
0.0%
Operating Income: -$26.31M
Revenue: $0.00
Revenue: $0.00
Net Margin (Revenue left as actual profit)
APINet Income / Revenue
0.0%
Net Income: -$25.97M
Revenue: $0.00
Revenue: $0.00
ROE (Profit from shareholder equity)
APINet Income / Total Equity
-198.5%
Net Income: -$25.97M
Total Equity: $17.38M
Total Equity: $17.38M
ROIC (Profit from all invested capital)
APINOPAT / Invested Capital
-166.3%
Operating Income: -$26.31M
Tax Rate: 0.0%
Equity: $17.38M
Total Debt: $866,000
Cash: $21.62M
Tax Rate: 0.0%
Equity: $17.38M
Total Debt: $866,000
Cash: $21.62M
Current Ratio (Can it pay short-term bills)
APICurrent Assets / Current Liabilities
3.82
Current Assets: $23.08M
Current Liabilities: $6.05M
Current Liabilities: $6.05M
Debt/Equity (Leverage — debt vs equity)
CALCTotal Debt / Total Equity
0.05
Short-Term Debt: $866,000
Long-Term Debt: $0.00
Total Debt: $866,000
Total Equity: $17.38M
Long-Term Debt: $0.00
Total Debt: $866,000
Total Equity: $17.38M
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
—
Revenue: $0.00
Shares: 3,155
Shares: 3,155
Book Value/Share (Net assets per share)
CALC(Total Assets - Total Liabilities) / Shares
$5,509.03
Total Equity: $17.38M
Shares: 3,155
Shares: 3,155
FCF/Share (Real cash generated per share)
CALC(Operating Cash Flow + CapEx) / Shares
$-8,111.57
Operating CF: -$25.59M
CapEx: $0.00
Shares: 3,155
CapEx: $0.00
Shares: 3,155
Div Yield (Annual income from holding)
APILast Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $3.94
Stock Price: $3.94
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
—
Dividends Paid: N/A
Net Income: -$25.97M
Net Income: -$25.97M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares APVO against LLM-researched typical ranges for its
industry. One research call per industry, cached indefinitely — every stock in the same industry
reuses the same baseline.
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
0
Company Classification
— What type of company is this?
1
Industry Landscape
— Where is the industry headed?
2
Company Momentum
— Where is this company trending?
3
Forward Projection
— 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a
DCF Valuation
— Present value of future cash flows
4b
Earnings Power Value
— Floor value — worth with zero growth
4c
Anchored PE
— Industry PE adjusted for growth differential
4d
Reverse DCF
— What growth is the market pricing in?
4e
Revenue-Based DCF
— For growth/narrative companies (skip if mature earner)
4f
Anchored P/S
— Price-to-Sales peer comparison (skip if mature earner)
4g
Scenario Analysis
— Bull / Base / Bear (skip if mature earner)
4h
Dividend Discount Model
— For dividend/income stocks only
4i
Book Value Analysis
— For deep value / turnaround stocks only
4j
Insider Activity
— Are insiders buying or selling?
4f
Cash Flow Quality
— How trustworthy is the FCF?
4g
Debt Maturity Risk
— Can it handle its debt?
4h
Macro Environment
— Rates, market valuation, volatility
4i
Sector Intelligence
— How does this company compare within its sector?
4j
Revenue Confidence
— How reliable is the growth projection?
4k
Sensitivity Analysis
— How fragile is the fair value estimate?
4l
Sector Demand Cycle
— Is the sector in a boom, steady state, or contraction?
5
AI Investigation
— Adaptive research engine (Claude)
5b
Thesis Evaluation
— What does the market believe? (narrative/platform stocks only)
6
Valuation Synthesis
— Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jul 10, 2026 3:07am (1h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $12.3M | $3.1M | $0 | $0 | $0 |
| Cost of Revenue | $0 | $0 | $0 | $352,000 | $240,000 |
| Gross Profit | $12.3M | $3.1M | $0 | $-352,000 | $-240,000 |
| Operating Expenses | $33.7M | $31.8M | $28.9M | $24.3M | $26.1M |
| Operating Income | -$21.4M | -$28.6M | -$28.9M | -$24.6M | -$26.3M |
| Net Income | -$28.5M | $8.0M | -$17.4M | -$24.1M | -$26.0M |
| EBITDA | -$28.3M | $7.9M | -$18.1M | -$23.8M | -$25.7M |
| EPS | $-3,557,646.00 | $922,390.00 | $-834,044.00 | $-31,458.00 | $-87.27 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jul 10, 2026 3:07am (1h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $45.0M | $22.6M | $16.9M | $8.7M | $21.6M |
| Total Current Assets | $52.6M | $27.5M | $19.1M | $10.7M | $23.1M |
| Total Assets | $56.6M | $34.2M | $24.8M | $15.6M | $27.2M |
| Current Liabilities | $34.8M | $8.7M | $7.2M | $6.2M | $6.1M |
| Long-Term Debt | $3.7M | $1.5M | $0 | $0 | $0 |
| Total Liabilities | $55.4M | $16.2M | $12.6M | $10.8M | $9.8M |
| Total Equity | $1.2M | $18.0M | $12.2M | $4.8M | $17.4M |
| Retained Earnings | -$214.1M | -$206.0M | -$223.4M | -$247.6M | -$275.1M |
Cash Flow (Annual)
Last updated: Jul 10, 2026 3:07am (1h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$21.7M | -$21.0M | -$11.7M | -$23.8M | -$25.6M |
| Capital Expenditure | $-713,000 | $-29,000 | $0 | $0 | $0 |
| Free Cash Flow | -$22.4M | -$21.1M | -$11.7M | -$23.8M | -$25.6M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $3.8M | -$23.7M | -$5.7M | -$8.2M | $12.9M |
Analyst Estimates (Annual)
Last updated: Jul 10, 2026 3:07am (1h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$6.7M $6.7M – $6.7M
|
$17.7M $17.7M – $17.7M
|
$21.3M $21.3M – $21.3M
|
$65.5M $65.5M – $65.5M
|
| EBITDA |
$4.0M $4.0M – $4.0M
|
$10.6M $10.6M – $10.6M
|
$12.8M $12.8M – $12.8M
|
$39.3M $39.3M – $39.3M
|
| Net Income |
$-38,250 $-67,727 – $-8,773
|
$-36,483 $-65,518 – $-7,448
|
$-16,884 $-16,884 – $-16,884
|
$51,411 $51,411 – $51,411
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jul 10, 2026 3:07am (1h ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | -74.7% | -100.0% | — | — |
| Gross Profit Growth | -74.7% | -100.0% | — | +31.8% |
| Operating Income Growth | -33.8% | -0.8% | +14.8% | -7.0% |
| Net Income Growth | +128.2% | -316.9% | -38.6% | -7.6% |
| EBITDA Growth | +128.0% | -328.5% | -31.5% | -8.2% |
Insider Trading (Recent)
Last updated: Jul 10, 2026 3:07am (1h ago)
Type codes
PPurchase
SSale
AAward / grant
MOption exercise
FIn-kind (tax)
CConversion
GGift
DReturn to issuer
All SEC Form 4 codes
Open market
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
Compensation (Rule 16b-3)
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
Other exempt
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
Other
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-05-25 | NIOWAVE, INC. | 0.00 | $0.00 | $0 | |
| 2026-05-25 | NIOWAVE, INC. | 53,201.00 | $8.00 | $425,608 | |
| 2026-05-20 | Janatpour Mary Jo | 0.00 | $0.00 | $0 | |
| 2025-11-10 | Grant Grady III | P-Purchase | 13,513.00 | $1.49 | $20,134 |
| 2025-10-01 | BANK OF AMERICA CORP /DE/ | 0.00 | $0.00 | $0 | |
| 2025-09-30 | BANK OF AMERICA CORP /DE/ | 0.00 | $0.00 | $0 | |
| 2025-08-06 | Abdun-Nabi Daniel | A-Award | 7,200.00 | $0.00 | $0 |
| 2025-08-06 | Taylor Daphne | A-Award | 11,500.00 | $0.00 | $0 |
| 2025-08-06 | Grant Grady III | A-Award | 7,200.00 | $0.00 | $0 |
| 2025-08-06 | Huebner Dirk | A-Award | 11,500.00 | $0.00 | $0 |
| 2025-08-06 | Niederhuber John | A-Award | 7,200.00 | $0.00 | $0 |
| 2025-08-06 | Lamothe Jeffrey G. | A-Award | 17,300.00 | $0.00 | $0 |
| 2025-08-06 | White Marvin L | A-Award | 30,000.00 | $0.00 | $0 |
| 2025-08-06 | Kunz Barbara Lopez | A-Award | 7,200.00 | $0.00 | $0 |
| 2025-08-06 | Kwon SoYoung | A-Award | 11,500.00 | $0.00 | $0 |
| 2025-08-06 | Harsanyi Zsolt | A-Award | 7,200.00 | $0.00 | $0 |
| 2025-07-17 | Harsanyi Zsolt | M-Exempt | 1.00 | $0.00 | $0 |
| 2025-07-17 | Harsanyi Zsolt | M-Exempt | 1.00 | $0.00 | $0 |
| 2025-07-17 | Kunz Barbara Lopez | M-Exempt | 1.00 | $0.00 | $0 |
| 2025-07-17 | Kunz Barbara Lopez | M-Exempt | 1.00 | $0.00 | $0 |
Narrative Economics
The story the market is telling about this stock — the intangible X-factor
(founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond
what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for APVO — it's generated by the pipeline (
market-narrative step).
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My Notes
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.397 · fd27f02b · 2026-07-09 18:28:55