Homepage

Curis, Inc.

CRIS NASDAQ Categories PDF
Healthcare · Biotechnology
Lexington, MA 02421, United States IPO 2000 curis.com Updated Jun 26, 4:47pm
Price
$0.31
Market Cap
$4.1M
Employees
24
Beta
3.08
Avg Volume
539,666
CEO
James Dentzer
Business Description

Curis, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small-molecule IRAK4 kinase inhibitor, which is in a Phase 1/2 open-label, single-arm expansion trial in patients with relapsed or refractory, or R/R, AML and high-risk myelodysplastic syndromes. The company’s pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma; CA-170, an oral, small-molecule antagonist designated as CA-170 that selectively targets PD-L1 and VISTA; and CA-327, an oral, small molecule, TIM3/PD-L1, which is a molecule antagonist of PD-L1 and TIM3. It has collaboration agreements with Genentech Inc., or Genentech and F. Hoffmann-La Roche Ltd, or Roche, for the commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway antagonist for the treatment of advanced basal cell carcinoma, or BCC; Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology; and also licensed three programs under the Aurigene collaboration, including emavusertib. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.

Business History
Price Overview
Last updated: Jun 27, 2026 8:03am (just now)
$0.32
+0.12 (+55.98%)
Day Range
$0.21 – $0.38
52-Week Range
$0.18 – $2.48
50-Day MA
$0.50
200-Day MA
$1.00
Volume
101,059,877.00
Share Structure
Outstanding 13,170,153.00
Float 10,907,079.00
Free Float 82.8%
High free float — 82.8% of shares trade freely, ~17.2% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Price History (1 Year)
Last updated: Jun 27, 2026 8:03am (just now)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jun 26, 2026 4:47pm (15h ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-0.54
Stock Price: $0.31
EPS (Diluted): -0.58
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
23.79
Stock Price: $0.31
Total Equity: $5.46M
Shares: 131,640,320
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
0.46
Market Cap: $4.12M
Total Debt: $1.19M
Cash: $5.06M
EBITDA: -$5.23M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$126.5M
Market Cap: $4.12M
Total Debt: $1.19M
Cash: $5.06M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
13.76
Stock Price: $0.31
Revenue: $9.44M
Shares: 131,640,320
EV/Sales (Total value vs revenue — works when P/E can't)
API
13.40
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
99.5%
Gross Profit: $9.40M
Revenue: $9.44M
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
-348.4%
Operating Income: -$32.90M
Revenue: $9.44M
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
-80.3%
Net Income: -$7.58M
Revenue: $9.44M
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
805.7%
Net Income: -$7.58M
Total Equity: $5.46M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-259.9%
Operating Income: -$32.90M
Tax Rate: 0.0%
Equity: $5.46M
Total Debt: $1.19M
Cash: $5.06M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
0.49
Current Assets: $6.92M
Current Liabilities: $14.08M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.22
Short-Term Debt: $1.19M
Long-Term Debt: $0.00
Total Debt: $1.19M
Total Equity: $5.46M
Rev/Share (Top-line per share)
CALC
Revenue / Shares Outstanding
$0.07
Revenue: $9.44M
Shares: 131,640,320
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$0.04
Total Equity: $5.46M
Shares: 131,640,320
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-0.21
Operating CF: -$27.20M
CapEx: $0.00
Shares: 131,640,320
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $0.31
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$7.58M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares CRIS against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 26, 2026 4:47pm (15h ago)
Metric 2021 2022 2023 2024 2025
Revenue $10.6M $10.2M $10.0M $10.9M $9.4M
Cost of Revenue $533,000 $257,000 $212,000 $98,000 $45,000
Gross Profit $10.1M $9.9M $9.8M $10.8M $9.4M
Operating Expenses $52.2M $62.9M $58.1M $55.4M $42.3M
Operating Income -$42.1M -$53.0M -$48.3M -$44.5M -$32.9M
Net Income -$45.4M -$56.7M -$47.4M -$43.4M -$7.6M
EBITDA -$40.8M -$51.7M -$45.1M -$42.6M -$5.2M
EPS $-9.92 $-12.14 $-8.96 $-6.88 $-0.58
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jun 26, 2026 4:47pm (15h ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $40.0M $19.7M $26.7M $20.0M $5.1M
Total Current Assets $122.4M $92.1M $60.9M $26.4M $6.9M
Total Assets $162.3M $108.8M $77.3M $41.3M $20.0M
Current Liabilities $13.4M $10.0M $22.0M $19.0M $14.1M
Long-Term Debt $0 $0 $0 $0 $0
Total Liabilities $71.6M $62.3M $57.6M $47.3M $14.5M
Total Equity $90.7M $46.6M $19.7M -$6.0M $5.5M
Retained Earnings -$1.1B -$1.1B -$1.2B -$1.2B -$1.2B
Cash Flow (Annual)
Last updated: Jun 26, 2026 4:47pm (15h ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$37.6M -$54.3M -$38.4M -$39.6M -$27.2M
Capital Expenditure $0 $-416,000 $0 $0 $0
Free Cash Flow -$37.6M -$54.8M -$38.4M -$39.6M -$27.2M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash -$89.7M -$20.4M $6.9M -$6.7M -$14.9M
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 4:47pm (15h ago)
Metric 2027 2028 2029 2030
Revenue $17.0M
$17.0M – $17.0M
$29.1M
$29.1M – $29.1M
$117.0M
$117.0M – $117.0M
$149.0M
$149.0M – $149.0M
EBITDA -$15.5M
-$15.5M – -$15.5M
-$26.5M
-$26.5M – -$26.5M
-$106.6M
-$106.6M – -$106.6M
-$135.7M
-$135.7M – -$135.7M
Net Income -$133.6M
-$180.6M – -$86.7M
-$40.0M
-$476.5M – $75.0M
$221.2M
$221.2M – $221.2M
$327.8M
$327.8M – $327.8M
EPS
Growth Trends (YoY %)
Last updated: Jun 26, 2026 4:47pm (15h ago)
Metric 2022 2023 2024 2025
Revenue Growth -4.6% -1.4% +8.8% -13.4%
Gross Profit Growth -2.1% -0.9% +10.2% -13.1%
Operating Income Growth -26.0% +8.8% +7.8% +26.1%
Net Income Growth -24.7% +16.3% +8.5% +82.5%
EBITDA Growth -26.6% +12.6% +5.7% +87.7%
Insider Trading (Recent)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-03-31 KAITIN KENNETH I P-Purchase 10,000.00 $0.55 $5,487
2026-03-20 Zung Jonathan B. C-Conversion 66,667.00 $0.00 $0
2026-03-20 Zung Jonathan B. C-Conversion 50.00 $0.00 $0
2026-03-20 Hamdy Ahmed MD C-Conversion 66,667.00 $0.00 $0
2026-03-20 Hamdy Ahmed MD C-Conversion 50.00 $0.00 $0
2026-03-20 Duvall Diantha C-Conversion 66,666.00 $0.00 $0
2026-03-20 Duvall Diantha C-Conversion 50.00 $0.00 $0
2026-03-20 Dentzer James E C-Conversion 133,333.00 $0.00 $0
2026-03-20 Dentzer James E C-Conversion 100.00 $0.00 $0
2026-03-20 Rubin Marc C-Conversion 26,667.00 $0.00 $0
2026-03-20 Rubin Marc C-Conversion 20.00 $0.00 $0
2026-03-17 Zung Jonathan B. A-Award 66,667.00 $0.75 $50,000
2026-03-17 Zung Jonathan B. A-Award 66,667.00 $0.75 $50,000
2026-03-17 Zung Jonathan B. A-Award 66,667.00 $0.75 $50,000
2026-03-17 Zung Jonathan B. A-Award 50.00 $0.00 $0
2026-03-17 Hamdy Ahmed MD A-Award 66,667.00 $0.75 $50,000
2026-03-17 Hamdy Ahmed MD A-Award 66,667.00 $0.75 $50,000
2026-03-17 Hamdy Ahmed MD A-Award 66,667.00 $0.75 $50,000
2026-03-17 Hamdy Ahmed MD A-Award 50.00 $0.00 $0
2026-03-17 Duvall Diantha A-Award 66,666.00 $0.75 $50,000
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for CRIS — it's generated by the pipeline (market-narrative step).
Community AI Feedback
No community reviews yet for CRIS. Be the first — hit How to Contribute, have any AI review this page, and paste its take back here.
My Notes personal — only you see this
Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30