Design Therapeutics, Inc.

DSGN NASDAQ Categories PDF
Healthcare · Biotechnology
Carlsbad, CA 92011, United States IPO 2021 designtx.com Updated May 13, 7:35am
Price
$15.79
Market Cap
$986.2M
Employees
56
Beta
1.74
Avg Volume
366,080
CEO
Pratik Shah
Business Description

Design Therapeutics, Inc. a preclinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of genetic diseases caused by nucleotide repeat expansions. The company's portfolio of products comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function, eventually leading to neurological, cardiac, and metabolic dysfunction; and Myotonic Dystrophy Type-1 (DM1), a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs. It is also developing GeneTAC product candidate portfolio for the treatment of other nucleotide repeat expansion-driven monogenic diseases, such as Fragile X syndrome, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia, Huntington disease, and spinobulbar muscular atrophy. Design Therapeutics, Inc. was incorporated in 2017 and is headquartered in Carlsbad, California.

Business History
Price Overview
Last updated: May 14, 2026 3:16am (just now)
$15.62
-0.17 (-1.08%)
Day Range
$15.23 – $15.95
52-Week Range
$3.11 – $17.25
50-Day MA
$12.10
200-Day MA
$8.81
Volume
752,413.00
Analyst Price Targets
Low $14.00
Consensus $17.50
High $21.00
(10 analysts)
Share Structure
Outstanding 62,456,974.00
Float 36,734,084.00
Free Float 58.8%
Normal free float — 58.8% of shares trade freely, ~41.2% held by insiders/institutions
Healthy float typical of established companies. Good liquidity for entering and exiting positions without major price impact.
Price History (1 Year)
Last updated: May 14, 2026 3:16am (just now)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: May 9, 2026 7:27pm (4d ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-12.94
Stock Price: $15.79
EPS (Diluted): -1.22
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
2.53
Stock Price: $15.79
Total Equity: $212.50M
Shares: 57,330,192
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-13.17
Market Cap: $986.20M
Total Debt: $645,000
Cash: $16.86M
EBITDA: -$78.85M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$521.5M
Market Cap: $986.20M
Total Debt: $645,000
Cash: $16.86M
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
0.0%
Gross Profit: -$622,000
Revenue: $0.00
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
0.0%
Operating Income: -$79.47M
Revenue: $0.00
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
0.0%
Net Income: -$69.79M
Revenue: $0.00
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-33.1%
Net Income: -$69.79M
Total Equity: $212.50M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-35.7%
Operating Income: -$79.47M
Tax Rate: 0.0%
Equity: $212.50M
Total Debt: $645,000
Cash: $16.86M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
17.14
Current Assets: $223.78M
Current Liabilities: $13.06M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.00
Short-Term Debt: $0.00
Long-Term Debt: $645,000
Total Debt: $645,000
Total Equity: $212.50M
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
Revenue: $0.00
Shares: 57,330,192
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$3.71
Total Equity: $212.50M
Shares: 57,330,192
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-0.95
Operating CF: -$54.36M
CapEx: -$193,000
Shares: 57,330,192
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $15.79
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$69.79M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares DSGN against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: May 9, 2026 7:27pm (4d ago)
Metric 2021 2022 2023 2024 2025
Revenue $0 $0 $0 $0 $0
Cost of Revenue $0 $466,000 $537,000 $596,000 $622,000
Gross Profit $0 $-466,000 $-537,000 $-596,000 $-622,000
Operating Expenses $35.8M $67.1M $77.7M $61.8M $78.8M
Operating Income -$35.8M -$67.6M -$78.2M -$62.4M -$79.5M
Net Income -$35.5M -$63.3M -$66.9M -$49.6M -$69.8M
EBITDA -$35.7M -$62.8M -$66.3M -$49.0M -$78.8M
EPS $-0.77 $-1.14 $-1.19 $-0.88 $-1.22
EPS (Diluted)
Balance Sheet (Annual)
Last updated: May 9, 2026 7:27pm (4d ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $298.6M $26.5M $21.2M $22.6M $16.9M
Total Current Assets $385.4M $335.1M $284.6M $248.0M $223.8M
Total Assets $390.6M $341.1M $289.6M $252.1M $226.2M
Current Liabilities $5.3M $10.8M $9.6M $8.5M $13.1M
Long-Term Debt $0 $0 $0 $0 $645,000
Total Liabilities $8.4M $13.8M $12.0M $10.0M $13.7M
Total Equity $382.1M $327.3M $277.7M $242.1M $212.5M
Retained Earnings -$47.5M -$110.8M -$177.6M -$227.2M -$297.0M
Cash Flow (Annual)
Last updated: May 9, 2026 7:27pm (4d ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$29.4M -$51.3M -$58.6M -$43.1M -$54.4M
Capital Expenditure -$1.5M $-918,000 $-256,000 $-340,000 $-193,000
Free Cash Flow -$30.9M -$52.2M -$58.8M -$43.4M -$54.6M
Acquisitions (net) $52,106 $39,000 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $296.2M -$272.1M -$5.3M $1.4M -$5.7M
Analyst Estimates (Annual)
Last updated: May 13, 2026 7:35am (19h ago)
Metric 2027 2028 2029 2030
Revenue $204.8M
$204.8M – $204.8M
$8.5M
$8.5M – $8.5M
$72.7M
$72.7M – $72.7M
$234.1M
$234.1M – $234.1M
EBITDA $0 $0 $0 $0
Net Income -$97.9M
-$116.5M – -$79.4M
-$114.0M
-$140.6M – -$87.3M
-$97.9M
-$97.9M – -$97.9M
-$27.4M
-$27.4M – -$27.4M
EPS
Growth Trends (YoY %)
Last updated: May 9, 2026 7:27pm (4d ago)
Metric 2022 2023 2024 2025
Revenue Growth
Gross Profit Growth -15.2% -11.0% -4.4%
Operating Income Growth -88.6% -15.7% +20.2% -27.4%
Net Income Growth -78.2% -5.6% +25.8% -40.7%
EBITDA Growth -76.0% -5.5% +26.1% -60.9%
Insider Trading (Recent)
Date Insider Type Shares Price Value
2026-03-31 Shapiro David A-Award 60,000.00 $10.64 $638,400
2026-03-31 Shapiro David A-Award 7,500.00 $10.64 $79,800
2026-03-31 Shapiro David 0.00 $0.00 $0
2026-01-02 Storgard Chris A-Award 250,000.00 $9.10 $2.3M
2026-01-02 Jeffries Sean A-Award 375,000.00 $9.10 $3.4M
2026-01-02 Burgess Julie A-Award 150,000.00 $9.10 $1.4M
2026-01-02 Gover Justin D. A-Award 45,000.00 $9.10 $409,500
2026-01-02 Shah Pratik A-Award 750,000.00 $9.10 $6.8M
2025-12-09 Shah Pratik A-Award 525,000.00 $2.48 $1.3M
2025-09-09 Gover Justin D. A-Award 30,000.00 $6.64 $199,200
2025-09-09 Gover Justin D. A-Award 15,833.00 $6.64 $105,131
2025-09-09 Gover Justin D. 0.00 $0.00 $0
2025-08-13 William Arsani S-Sale 345,000.00 $5.25 $1.8M
2025-08-13 William Arsani S-Sale 217,627.00 $5.25 $1.1M
2025-06-10 George Simeon A-Award 19,000.00 $4.01 $76,190
2025-06-10 Prasad Deepa A-Award 19,000.00 $4.01 $76,190
2025-06-10 William Arsani A-Award 19,000.00 $4.01 $76,190
2025-06-10 Berger Heather A. A-Award 19,000.00 $4.01 $76,190
2025-06-10 Schmid John P. A-Award 19,000.00 $4.01 $76,190
2025-06-10 LAPPE RODNEY W A-Award 19,000.00 $4.01 $76,190
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My Notes personal — only you see this
Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.207 · 22a3a690 · 2026-05-13 17:39:54