Precision BioSciences, Inc. is a clinical-stage biotechnology firm based in the United States, specializing in the creation of both in vivo gene editing solutions and ex vivo allogeneic CAR T-cell therapies. At its core is ARCUS, a proprietary genome editing platform designed to address and potentially cure genetic diseases. The company's portfolio also encompasses Ex vivo Allogeneic CAR T Immunotherapy, an innovative approach where specific immune cells, known as T-cells, are genetically modified outside the body to precisely identify and eliminate cancer cells. Among its prominent therapeutic candidates are: PBCAR0191, currently undergoing Phase 1/2a clinical trials for adult patients battling relapsed/refractory (R/R) non-Hodgkin lymphoma or R/R B-cell precursor acute lymphoblastic leukemia (B-ALL). PBCAR19B, an anti-CD19 CAR T candidate leveraging a "stealth cell" platform through a single-step gene edit, engineered to reduce the likelihood of chromosomal abnormalities. PBCAR269A, an investigational allogeneic CAR T immunotherapy formulated to target BCMA, intended for the treatment of R/R multiple myeloma. Precision BioSciences has strategically formed several collaborative alliances. These include an agreement with Les Laboratoires Servier for the development and commercialization of allogeneic chimeric antigen receptor T-cell therapies, aimed at various antigen targets, including hematological cancers beyond CD19, and solid tumors. The company is also partnering with Tiziana Life Sciences to assess foralumab, a fully human anti-CD3 monoclonal antibody, for its utility as a lymphodepleting agent in potential cancer treatments. Furthermore, a collaboration with iECURE, Inc. focuses on advancing ARCUS-based gene editing therapies. Established in 2006, Precision BioSciences, Inc. maintains its corporate headquarters in Durham, North Carolina.
Price Overview
Last updated: Jul 8, 2026 7:17pm (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -3.56
Total Equity: $92.25M
Shares: 12,826,078
Total Debt: $22.40M
Cash: $110.82M
EBITDA: -$42.43M
Total Debt: $22.40M
Cash: $110.82M
Revenue: $34.26M
Shares: 12,826,078
Revenue: $34.26M
Revenue: $34.26M
Revenue: $34.26M
Total Equity: $92.25M
Tax Rate: 0.0%
Equity: $92.25M
Total Debt: $22.40M
Cash: $110.82M
Current Liabilities: $8.91M
Long-Term Debt: $22.40M
Total Debt: $22.40M
Total Equity: $92.25M
Shares: 12,826,078
Shares: 12,826,078
CapEx: -$85,000
Shares: 12,826,078
Stock Price: $9.28
Net Income: -$45.72M
Industry Benchmarks
Deep Analysis
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Income Statement (Annual)
Last updated: Jul 7, 2026 6:18pm (1d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $115.5M | $25.1M | $48.7M | $68.7M | $34.3M |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $115.5M | $25.1M | $48.7M | $68.7M | $34.3M |
| Operating Expenses | $154.9M | $87.4M | $92.5M | $94.9M | $86.4M |
| Operating Income | -$39.4M | -$62.3M | -$43.7M | -$26.2M | -$52.1M |
| Net Income | -$30.6M | -$111.6M | -$61.3M | $7.2M | -$45.7M |
| EBITDA | -$20.3M | -$62.8M | -$32.0M | $13.5M | -$42.4M |
| EPS | $-15.60 | $-38.10 | $-15.96 | $1.05 | $-3.56 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jul 7, 2026 6:18pm (1d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $143.7M | $189.6M | $116.7M | $85.9M | $110.8M |
| Total Current Assets | $161.8M | $199.1M | $136.4M | $95.0M | $118.7M |
| Total Assets | $211.5M | $238.2M | $159.8M | $136.4M | $154.4M |
| Current Liabilities | $36.0M | $59.7M | $50.0M | $15.0M | $8.9M |
| Long-Term Debt | $2.5M | $22.2M | $0 | $22.3M | $22.4M |
| Total Liabilities | $120.3M | $177.7M | $140.9M | $80.0M | $62.2M |
| Total Equity | $91.2M | $60.4M | $18.9M | $56.4M | $92.2M |
| Retained Earnings | -$316.7M | -$428.3M | -$489.6M | -$482.5M | -$528.2M |
Cash Flow (Annual)
Last updated: Jul 7, 2026 6:18pm (1d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$10.9M | -$45.8M | -$84.1M | -$58.4M | -$65.8M |
| Capital Expenditure | -$5.8M | -$3.3M | -$2.3M | $-250,000 | $-85,000 |
| Free Cash Flow | -$16.7M | -$49.1M | -$86.4M | -$58.7M | -$65.9M |
| Acquisitions (net) | $0 | $0 | $8.0M | $60,000 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $53.9M | $45.9M | -$72.9M | -$8.2M | $28.7M |
Analyst Estimates (Annual)
Last updated: Jul 8, 2026 7:17pm (just now)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$14.4M $9.0M – $19.8M
|
$18.5M $10.2M – $29.3M
|
$25.4M $14.0M – $40.4M
|
$120.6M $66.5M – $191.5M
|
| EBITDA |
-$7.6M -$10.5M – -$4.7M
|
-$9.7M -$15.5M – -$5.4M
|
-$13.4M -$21.3M – -$7.4M
|
-$63.6M -$101.0M – -$35.0M
|
| Net Income |
-$29.5M -$34.9M – -$24.1M
|
-$28.2M -$37.9M – -$18.5M
|
-$27.1M -$47.9M – -$11.3M
|
-$7.9M -$14.0M – -$3.3M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jul 7, 2026 6:18pm (1d ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | -78.3% | +94.1% | +41.0% | -50.1% |
| Gross Profit Growth | -78.3% | +94.1% | +41.0% | -50.1% |
| Operating Income Growth | -58.2% | +29.8% | +40.2% | -99.3% |
| Net Income Growth | -264.8% | +45.1% | +111.7% | -738.0% |
| EBITDA Growth | -209.7% | +49.0% | +142.2% | -413.7% |
Insider Trading (Recent)
All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-03 | Brown Melinda | A-Award | 20,979.00 | $0.00 | $0 |
| 2026-06-03 | Frankel Stanley | A-Award | 20,979.00 | $0.00 | $0 |
| 2026-06-03 | Germano Geno J | A-Award | 20,979.00 | $0.00 | $0 |
| 2026-06-03 | Pire Shari Lisa | A-Award | 20,979.00 | $0.00 | $0 |
| 2026-06-03 | Buehler Kevin | A-Award | 20,979.00 | $0.00 | $0 |
| 2026-05-20 | Buehler Kevin | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Buehler Kevin | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Frankel Stanley | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Frankel Stanley | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Brown Melinda | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Brown Melinda | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Pire Shari Lisa | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Pire Shari Lisa | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Germano Geno J | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-05-20 | Germano Geno J | M-Exempt | 21,000.00 | $0.00 | $0 |
| 2026-02-17 | Amoroso Michael | M-Exempt | 67,797.00 | $0.00 | $0 |
| 2026-02-18 | Amoroso Michael | S-Sale | 20,559.00 | $3.84 | $78,947 |
| 2026-02-17 | Amoroso Michael | M-Exempt | 67,797.00 | $0.00 | $0 |
| 2026-02-17 | Kelly John Alexander | M-Exempt | 27,584.00 | $0.00 | $0 |
| 2026-02-18 | Kelly John Alexander | S-Sale | 8,149.00 | $3.84 | $31,292 |
Narrative Economics
market-narrative step).