Business Description
Equillium, Inc. is a clinical-stage biopharmaceutical company focused on developing and bringing to market products designed to address severe autoimmune and inflammatory (immuno-inflammatory) disorders where current treatment options are insufficient. The company's primary drug candidate is itolizumab (EQ001), a monoclonal antibody in clinical development that targets the novel CD6 immune checkpoint receptor. Itolizumab is currently in Phase III trials for acute graft-versus-host disease, has completed Phase Ib studies for asthma, and is also undergoing Phase Ib trials for lupus nephritis. In addition to itolizumab, Equillium is advancing EQ101 for the treatment of cutaneous T cell lymphoma and alopecia areata, and EQ102, which targets various gastrointestinal conditions. Headquartered in La Jolla, California, the company was incorporated in 2017 and previously operated as Attenuate Biopharmaceuticals, Inc. before changing its name to Equillium, Inc. in May 2017.
Business History
Price Overview
Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -0.39
Total Equity: $28.60M
Shares: 91,881,058
Total Debt: $719,000
Cash: $30.28M
EBITDA: -$22.28M
Total Debt: $719,000
Cash: $30.28M
Revenue: $0.00
Shares: 91,881,058
Revenue: $0.00
Revenue: $0.00
Revenue: $0.00
Total Equity: $28.60M
Tax Rate: 0.0%
Equity: $28.60M
Total Debt: $719,000
Cash: $30.28M
Current Liabilities: $2.93M
Long-Term Debt: $356,000
Total Debt: $719,000
Total Equity: $28.60M
Shares: 91,881,058
Shares: 91,881,058
CapEx: -$48,000
Shares: 91,881,058
Stock Price: $2.91
Net Income: -$22.40M
Industry Benchmarks
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
Income Statement (Annual)
Last updated: Jul 3, 2026 4:50am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $15.8M | $36.1M | $41.1M | $0 |
| Cost of Revenue | $0 | $0 | $0 | $0 | $116,000 |
| Gross Profit | $0 | $15.8M | $36.1M | $41.1M | $-116,000 |
| Operating Expenses | $37.8M | $77.8M | $50.6M | $49.4M | $23.6M |
| Operating Income | -$37.8M | -$62.1M | -$14.5M | -$8.3M | -$23.6M |
| Net Income | -$39.0M | -$62.4M | -$13.3M | -$8.1M | -$22.4M |
| EBITDA | -$37.9M | -$61.3M | -$12.1M | -$7.6M | -$22.3M |
| EPS | $-1.35 | $-3.19 | $-0.38 | $-0.23 | $-0.39 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jul 3, 2026 4:50am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $50.4M | $59.1M | $23.2M | $18.1M | $30.3M |
| Total Current Assets | $83.4M | $76.7M | $49.3M | $25.0M | $30.3M |
| Total Assets | $85.4M | $78.4M | $50.5M | $25.6M | $31.9M |
| Current Liabilities | $8.9M | $32.0M | $27.6M | $6.4M | $2.9M |
| Long-Term Debt | $8.8M | $3.2M | $0 | $0 | $356,000 |
| Total Liabilities | $18.9M | $46.5M | $28.0M | $6.5M | $3.3M |
| Total Equity | $66.5M | $31.9M | $22.6M | $19.1M | $28.6M |
| Retained Earnings | -$110.0M | -$172.4M | -$185.7M | -$193.8M | -$216.2M |
Cash Flow (Annual)
Last updated: Jul 3, 2026 4:50am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$32.1M | -$8.7M | -$21.8M | -$19.0M | -$22.7M |
| Capital Expenditure | $-57,000 | $-279,000 | $-50,000 | $-85,000 | $-48,000 |
| Free Cash Flow | -$32.1M | -$9.0M | -$21.8M | -$19.1M | -$22.8M |
| Acquisitions (net) | $0 | $700,000 | $0 | $0 | $12,000 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $-260,000 | $0 | $0 |
| Net Change in Cash | $26.4M | $8.7M | -$35.9M | -$5.1M | $12.2M |
Analyst Estimates (Annual)
Last updated: Jul 3, 2026 4:50am (just now)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$16.5M $16.5M – $16.5M
|
$51.7M $51.7M – $51.7M
|
$89.2M $89.2M – $89.2M
|
$0 |
| EBITDA |
$1.6M $1.6M – $1.6M
|
$5.0M $5.0M – $5.0M
|
$8.6M $8.6M – $8.6M
|
$0 |
| Net Income |
-$25.1M -$31.3M – -$19.0M
|
-$30.4M -$40.5M – -$20.3M
|
-$30.6M -$30.6M – -$30.6M
|
-$37.7M -$37.7M – -$37.7M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jul 3, 2026 4:50am (just now)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | +129.0% | +13.9% | -100.0% |
| Gross Profit Growth | — | +129.0% | +13.9% | -100.3% |
| Operating Income Growth | -64.3% | +76.6% | +43.1% | -185.8% |
| Net Income Growth | -60.2% | +78.6% | +39.5% | -177.6% |
| EBITDA Growth | -61.6% | +80.2% | +37.6% | -194.4% |
Insider Trading (Recent)
All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-05 | Zedelmayer Christine | M-Exempt | 14,584.00 | $0.79 | $11,448 |
| 2026-06-05 | Zedelmayer Christine | S-Sale | 14,584.00 | $2.93 | $42,737 |
| 2026-06-05 | Zedelmayer Christine | M-Exempt | 14,584.00 | $0.79 | $11,448 |
| 2026-06-04 | Connelly Stephen | S-Sale | 200,000.00 | $3.16 | $632,760 |
| 2026-06-05 | Connelly Stephen | S-Sale | 30,975.00 | $2.94 | $91,070 |
| 2026-05-28 | Tom Penny | M-Exempt | 65,000.00 | $0.79 | $51,025 |
| 2026-05-28 | Tom Penny | S-Sale | 65,000.00 | $2.95 | $191,750 |
| 2026-05-28 | Tom Penny | M-Exempt | 65,000.00 | $0.79 | $51,025 |
| 2026-05-28 | DEMSKI MARTHA J | A-Award | 70,000.00 | $2.84 | $198,800 |
| 2026-05-28 | Pruzanski Mark | A-Award | 70,000.00 | $2.84 | $198,800 |
| 2026-05-28 | BRADBURY DANIEL | A-Award | 70,000.00 | $2.84 | $198,800 |
| 2026-05-27 | Zedelmayer Christine | M-Exempt | 9,821.00 | $0.77 | $7,562 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 48,512.00 | $0.77 | $37,354 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 48,512.00 | $0.77 | $37,354 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 15,625.00 | $0.79 | $12,266 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 7,292.00 | $0.73 | $5,323 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 14,583.00 | $0.79 | $11,448 |
| 2026-05-27 | Zedelmayer Christine | M-Exempt | 9,821.00 | $0.77 | $7,562 |
| 2026-05-28 | Zedelmayer Christine | M-Exempt | 7,292.00 | $0.73 | $5,323 |
| 2026-05-28 | Zedelmayer Christine | S-Sale | 55,604.00 | $2.70 | $150,131 |
Narrative Economics
market-narrative step).