Healthcare · Biotechnology
Price
$0.42
Market Cap
$4.5M
Employees
1
Beta
0.86
Avg Volume
1,395,429
CEO
Michael Martin Breen
Business Description
GT Biopharma, Inc. is a biopharmaceutical company in the clinical development phase, dedicated to discovering and bringing to market novel immuno-oncology treatments. Their innovative approach centers on a proprietary technology platform called Tri-specific Killer Engager (TriKE) fusion proteins, which are designed to harness the body's immune cells. Central to their pipeline is GTB-3550, a single-chain tri-specific recombinant fusion protein conjugate currently undergoing Phase I/II clinical trials. This therapeutic candidate is being evaluated for its potential in treating myelodysplastic syndromes, acute myeloid leukemia that has relapsed or proven refractory to prior treatments, advanced systemic mastocytosis, and other malignancies expressing CD33. The company's research also includes GTB-3650, which is in preclinical development targeting CD33 on myeloid leukemias, and GTB-5550, another preclinical asset aimed at solid tumors that are positive for B7-H3. GT Biopharma has forged key collaborations, including a co-development agreement with Altor BioScience Corporation for the clinical advancement of a 161533 TriKE fusion protein for various cancer indications. Furthermore, they maintain a license agreement with the Regents of the University of Minnesota to develop and commercialize cancer therapies utilizing their TriKE technology. Founded in 1965, the company previously operated as OXIS International, Inc. before rebranding to GT Biopharma, Inc. in July 2017. Its corporate operations are based in Brisbane, California.
Business History
Price Overview
Last updated: Jun 27, 2026 9:03am (just now)$0.43
+0.01 (+3.34%)
Day Range
$0.42 – $0.46
52-Week Range
$0.26 – $3.73
50-Day MA
$0.40
200-Day MA
$0.57
Volume
838,863.00
Share Structure
Outstanding
10,621,848.00
Float
10,303,011.00
Free Float
97.0%
High free float
— 97.0% of shares trade freely, ~3% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Price History (1 Year)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
API Direct from provider
CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALCStock Price / EPS (Diluted)
-0.07
Stock Price: $0.42
EPS (Diluted): -6.25
EPS (Diluted): -6.25
P/B Ratio (Price vs net asset value)
APIStock Price / Book Value Per Share
0.75
Stock Price: $0.42
Total Equity: $5.79M
Shares: 5,513,255
Total Equity: $5.79M
Shares: 5,513,255
EV/EBITDA (Total value vs operating profit)
APIEnterprise Value / EBITDA
0.09
Market Cap: $4.50M
Total Debt: $0.00
Cash: $6.81M
EBITDA: -$28.23M
Total Debt: $0.00
Cash: $6.81M
EBITDA: -$28.23M
Enterprise Value (Takeover price (cap + debt - cash))
APIMarket Cap + Total Debt - Cash
-$2.5M
Market Cap: $4.50M
Total Debt: $0.00
Cash: $6.81M
Total Debt: $0.00
Cash: $6.81M
P/S Ratio (Price per dollar of revenue)
APIStock Price / Revenue Per Share
0.00
Stock Price: $0.42
Revenue: $0.00
Shares: 5,513,255
Revenue: $0.00
Shares: 5,513,255
EV/Sales (Total value vs revenue — works when P/E can't)
API0.00
Gross Margin (Revenue left after direct costs)
APIGross Profit / Revenue
0.0%
Gross Profit: $0.00
Revenue: $0.00
Revenue: $0.00
Operating Margin (Revenue left after all operations)
APIOperating Income / Revenue
0.0%
Operating Income: -$12.42M
Revenue: $0.00
Revenue: $0.00
Net Margin (Revenue left as actual profit)
APINet Income / Revenue
0.0%
Net Income: -$28.35M
Revenue: $0.00
Revenue: $0.00
ROE (Profit from shareholder equity)
APINet Income / Total Equity
-901.3%
Net Income: -$28.35M
Total Equity: $5.79M
Total Equity: $5.79M
ROIC (Profit from all invested capital)
APINOPAT / Invested Capital
-205.0%
Operating Income: -$12.42M
Tax Rate: 0.0%
Equity: $5.79M
Total Debt: $0.00
Cash: $6.81M
Tax Rate: 0.0%
Equity: $5.79M
Total Debt: $0.00
Cash: $6.81M
Zero debt — invested capital = equity minus cash (very efficient)
Current Ratio (Can it pay short-term bills)
APICurrent Assets / Current Liabilities
3.50
Current Assets: $8.11M
Current Liabilities: $2.32M
Current Liabilities: $2.32M
Debt/Equity (Leverage — debt vs equity)
CALCTotal Debt / Total Equity
0.00
Short-Term Debt: $0.00
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $5.79M
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $5.79M
Zero debt — this company carries no debt obligations. Strongest possible score.
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
—
Revenue: $0.00
Shares: 5,513,255
Shares: 5,513,255
Book Value/Share (Net assets per share)
CALC(Total Assets - Total Liabilities) / Shares
$1.05
Total Equity: $5.79M
Shares: 5,513,255
Shares: 5,513,255
FCF/Share (Real cash generated per share)
CALC(Operating Cash Flow + CapEx) / Shares
$-2.34
Operating CF: -$12.91M
CapEx: $0.00
Shares: 5,513,255
CapEx: $0.00
Shares: 5,513,255
Div Yield (Annual income from holding)
APILast Annual Dividend / Stock Price
5.3%
Last Dividend: N/A
Stock Price: $0.42
Stock Price: $0.42
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
—
Dividends Paid: N/A
Net Income: -$28.35M
Net Income: -$28.35M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares GTBP against LLM-researched typical ranges for its
industry. One research call per industry, cached indefinitely — every stock in the same industry
reuses the same baseline.
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
0
Company Classification
— What type of company is this?
1
Industry Landscape
— Where is the industry headed?
2
Company Momentum
— Where is this company trending?
3
Forward Projection
— 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a
DCF Valuation
— Present value of future cash flows
4b
Earnings Power Value
— Floor value — worth with zero growth
4c
Anchored PE
— Industry PE adjusted for growth differential
4d
Reverse DCF
— What growth is the market pricing in?
4e
Revenue-Based DCF
— For growth/narrative companies (skip if mature earner)
4f
Anchored P/S
— Price-to-Sales peer comparison (skip if mature earner)
4g
Scenario Analysis
— Bull / Base / Bear (skip if mature earner)
4h
Dividend Discount Model
— For dividend/income stocks only
4i
Book Value Analysis
— For deep value / turnaround stocks only
4j
Insider Activity
— Are insiders buying or selling?
4f
Cash Flow Quality
— How trustworthy is the FCF?
4g
Debt Maturity Risk
— Can it handle its debt?
4h
Macro Environment
— Rates, market valuation, volatility
4i
Sector Intelligence
— How does this company compare within its sector?
4j
Revenue Confidence
— How reliable is the growth projection?
4k
Sensitivity Analysis
— How fragile is the fair value estimate?
4l
Sector Demand Cycle
— Is the sector in a boom, steady state, or contraction?
5
AI Investigation
— Adaptive research engine (Claude)
5b
Thesis Evaluation
— What does the market believe? (narrative/platform stocks only)
6
Valuation Synthesis
— Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 24, 2026 4:26am (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $0 | $0 | $0 | $0 | $0 |
| Operating Expenses | $57.5M | $21.3M | $13.6M | $14.4M | $12.4M |
| Operating Income | -$57.5M | -$21.3M | -$13.6M | -$14.4M | -$12.4M |
| Net Income | -$58.0M | -$20.9M | -$7.6M | -$13.2M | -$28.4M |
| EBITDA | -$57.5M | -$21.0M | $6.0M | -$13.2M | -$28.2M |
| EPS | $-2.06 | $-0.66 | $-5.64 | $-6.94 | $-6.25 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 24, 2026 4:26am (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $9.0M | $5.7M | $1.1M | $4.0M | $6.8M |
| Total Current Assets | $32.2M | $16.6M | $14.1M | $4.2M | $8.1M |
| Total Assets | $32.2M | $16.7M | $14.1M | $4.2M | $8.1M |
| Current Liabilities | $10.3M | $4.9M | $6.6M | $5.9M | $2.3M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $10.3M | $5.0M | $6.6M | $5.9M | $2.3M |
| Total Equity | $21.9M | $11.7M | $7.5M | -$1.7M | $5.8M |
| Retained Earnings | -$653.6M | -$674.5M | -$682.1M | -$695.2M | -$723.9M |
Cash Flow (Annual)
Last updated: Jun 24, 2026 4:26am (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$15.6M | -$15.2M | -$8.9M | -$12.9M | -$12.9M |
| Capital Expenditure | $0 | $0 | $0 | $0 | $0 |
| Free Cash Flow | -$15.6M | -$15.2M | -$8.9M | -$12.9M | -$12.9M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $-224,000 | $0 | $0 | $0 |
| Net Change in Cash | $3.7M | -$3.3M | -$4.6M | $3.0M | $2.9M |
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 10:55am (22h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$67.7M $67.7M – $67.7M
|
$0 |
$20.1M $20.1M – $20.1M
|
$59.9M $59.9M – $59.9M
|
| EBITDA | $0 | $0 | $0 | $0 |
| Net Income |
-$1.5M -$1.5M – -$1.5M
|
-$1.3M -$1.3M – -$1.3M
|
$275,662 $275,662 – $275,662
|
$2.0M $2.0M – $2.0M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 24, 2026 4:26am (3d ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | — | — | — |
| Gross Profit Growth | — | — | — | — |
| Operating Income Growth | +63.0% | +36.1% | -5.8% | +13.5% |
| Net Income Growth | +64.0% | +63.6% | -73.3% | -115.4% |
| EBITDA Growth | +63.5% | +128.5% | -320.1% | -114.5% |
Insider Trading (Recent)
Last updated: Jun 27, 2026 8:29am (33m ago)
Type codes
PPurchase
SSale
AAward / grant
MOption exercise
FIn-kind (tax)
CConversion
GGift
DReturn to issuer
All SEC Form 4 codes
Open market
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
Compensation (Rule 16b-3)
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
Other exempt
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
Other
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2025-09-04 | Mun-Gavin David C. | A-Award | 31,250.00 | $1.33 | $41,563 |
| 2025-09-04 | Breen Michael Martin | A-Award | 100,000.00 | $1.33 | $133,000 |
| 2025-09-04 | URBAN ALAN LOUIS | A-Award | 50,000.00 | $1.33 | $66,500 |
| 2025-09-04 | CASAMENTO CHARLES J | A-Award | 62,500.00 | $1.33 | $83,125 |
| 2025-09-04 | Kramer Hilary | A-Award | 31,250.00 | $1.33 | $41,563 |
| 2025-06-10 | Mun-Gavin David C. | 0.00 | $0.00 | $0 | |
| 2025-05-07 | Kramer Hilary | 0.00 | $0.00 | $0 | |
| 2025-05-08 | Ritter Andrew J | 0.00 | $0.00 | $0 | |
| 2024-10-17 | URBAN ALAN LOUIS | A-Award | 23,335.00 | $2.11 | $49,237 |
| 2024-06-03 | URBAN ALAN LOUIS | 0.00 | $0.00 | $0 | |
| 2023-08-11 | Breen Michael Martin | A-Award | 200,000.00 | $0.29 | $57,400 |
| 2023-08-11 | Ohri Manu | J-Other | 200,000.00 | $0.29 | $57,400 |
| 2023-08-11 | Ohri Manu | A-Award | 200,000.00 | $0.29 | $57,400 |
| 2023-08-11 | Ohri Manu | J-Other | 200,000.00 | $0.29 | $57,400 |
| 2023-06-16 | CASAMENTO CHARLES J | A-Award | 500,000.00 | $0.35 | $175,000 |
| 2023-05-01 | CASAMENTO CHARLES J | 0.00 | $0.00 | $0 | |
| 2023-04-11 | Breen Michael Martin | P-Purchase | 50,000.00 | $0.50 | $25,000 |
| 2023-04-06 | Ohri Manu | P-Purchase | 50,000.00 | $0.50 | $25,000 |
| 2023-01-27 | Breen Michael Martin | A-Award | 500,000.00 | $0.84 | $418,500 |
| 2023-01-27 | SHROTRIYA RAJESH C MD | A-Award | 500,000.00 | $0.84 | $418,500 |
Narrative Economics
The story the market is telling about this stock — the intangible X-factor
(founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond
what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for GTBP — it's generated by the pipeline (
market-narrative step).
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My Notes
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30