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Werewolf Therapeutics, Inc.

HOWL NASDAQ Categories PDF
Healthcare · Biotechnology
Watertown, MA 02138, United States IPO 2021 werewolftx.com Updated Jun 30, 7:40pm
Price
$0.36
Market Cap
$17.5M
Employees
46
Beta
0.27
Avg Volume
583,530
CEO
Daniel J. Hicklin
Business Description

Werewolf Therapeutics, Inc. is a biopharmaceutical firm dedicated to developing novel therapies that activate the body's immune system to combat cancer. Leveraging its exclusive PREDATOR platform, the company crafts conditionally activated molecules designed to stimulate both adaptive and innate immunity. This strategic approach aims to circumvent the shortcomings often associated with traditional proinflammatory immune treatments. Key among its product pipeline are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule targeting advanced solid tumors, and WTX-330, an Interleukin-12 INDUKINE molecule also designed for conditional activation, intended for advanced or metastatic solid tumors or lymphomas that have relapsed or are refractory. Furthermore, Werewolf Therapeutics is progressing WTX-613, a conditionally activated interferon alpha INDUKINE molecule, for addressing solid tumors and hematologic malignancies. The company was founded in 2017 and operates from its headquarters in Cambridge, Massachusetts.

Business History
Price Overview
Last updated: Jun 30, 2026 9:35pm (just now)
$0.36
+0.05 (+16.85%)
Day Range
$0.30 – $0.36
52-Week Range
$0.27 – $2.38
50-Day MA
$0.54
200-Day MA
$0.91
Volume
1,299,060.00
Analyst Price Targets
Low $1.00
Consensus $6.50
High $12.00
(2 analysts)
Share Structure
Outstanding 48,596,800.00
Float 40,093,040.00
Free Float 82.5%
High free float — 82.5% of shares trade freely, ~17.5% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Price History (1 Year)
Last updated: Jun 30, 2026 9:35pm (just now)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jun 30, 2026 9:35pm (just now)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-0.27
Stock Price: $0.36
EPS (Diluted): -1.32
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
1.18
Stock Price: $0.36
Total Equity: $24.81M
Shares: 46,810,252
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-0.17
Market Cap: $17.49M
Total Debt: $1.75M
Cash: $57.95M
EBITDA: -$53.91M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
-$19.4M
Market Cap: $17.49M
Total Debt: $1.75M
Cash: $57.95M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
0.00
Stock Price: $0.36
Revenue: $0.00
Shares: 46,810,252
EV/Sales (Total value vs revenue — works when P/E can't)
API
0.00
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
0.0%
Gross Profit: -$1.63M
Revenue: $0.00
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
0.0%
Operating Income: -$60.68M
Revenue: $0.00
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
0.0%
Net Income: -$60.82M
Revenue: $0.00
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-208.2%
Net Income: -$60.82M
Total Equity: $24.81M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-103.4%
Operating Income: -$60.68M
Tax Rate: 0.0%
Equity: $24.81M
Total Debt: $1.75M
Cash: $57.95M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
1.62
Current Assets: $58.59M
Current Liabilities: $36.15M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.07
Short-Term Debt: $1.75M
Long-Term Debt: $0.00
Total Debt: $1.75M
Total Equity: $24.81M
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
Revenue: $0.00
Shares: 46,810,252
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$0.53
Total Equity: $24.81M
Shares: 46,810,252
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-1.29
Operating CF: -$60.29M
CapEx: $0.00
Shares: 46,810,252
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $0.36
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$60.82M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares HOWL against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 30, 2026 9:35pm (just now)
Metric 2021 2022 2023 2024 2025
Revenue $0 $16.4M $19.9M $1.9M $0
Cost of Revenue $0 $2.5M $1.8M $1.8M $1.6M
Gross Profit $0 $13.9M $18.2M $71,000 -$1.6M
Operating Expenses $50.1M $69.9M $58.7M $73.7M $59.0M
Operating Income -$50.1M -$56.1M -$40.5M -$73.6M -$60.7M
Net Income -$50.0M -$53.8M -$37.4M -$70.5M -$60.8M
EBITDA -$49.8M -$51.3M -$32.5M -$64.0M -$53.9M
EPS $-10.94 $-1.86 $-1.05 $-1.63 $-1.32
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jun 30, 2026 9:35pm (just now)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $157.5M $129.3M $134.3M $111.0M $58.0M
Total Current Assets $161.1M $140.2M $138.4M $113.1M $58.6M
Total Assets $179.3M $160.2M $174.8M $126.9M $69.4M
Current Liabilities $11.9M $24.0M $19.4M $15.2M $36.1M
Long-Term Debt $0 $0 $32.7M $26.1M $0
Total Liabilities $26.5M $37.9M $63.5M $53.5M $44.6M
Total Equity $152.8M $122.3M $111.4M $73.4M $24.8M
Retained Earnings -$252.9M -$306.7M -$344.1M -$414.6M -$475.4M
Cash Flow (Annual)
Last updated: Jun 30, 2026 9:35pm (just now)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$42.9M -$40.6M -$32.6M -$56.2M -$60.3M
Capital Expenditure $-498,000 -$3.6M $-769,000 $-254,000 $0
Free Cash Flow -$43.4M -$44.2M -$33.4M -$56.4M -$60.3M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $66.1M -$28.3M $25.0M -$43.4M -$54.3M
Analyst Estimates (Annual)
Last updated: Jun 30, 2026 9:35pm (just now)
Metric 2026 2027 2028 2029
Revenue $8.3M
$8.3M – $8.3M
$3.1M
$3.1M – $3.1M
$50,000
$50,000 – $50,000
$18.0M
$18.0M – $18.0M
EBITDA -$1.7M
-$1.7M – -$1.7M
$-619,999
$-619,999 – $-619,999
$-9,999
$-9,999 – $-9,999
-$3.6M
-$3.6M – -$3.6M
Net Income -$46.4M
-$49.0M – -$34.3M
-$74.7M
-$74.7M – -$74.7M
-$68.8M
-$68.8M – -$68.8M
-$46.1M
-$46.1M – -$46.1M
EPS
Growth Trends (YoY %)
Last updated: Jun 30, 2026 9:35pm (just now)
Metric 2022 2023 2024 2025
Revenue Growth +21.6% -90.5% -100.0%
Gross Profit Growth +30.9% -99.6% -2,401.4%
Operating Income Growth -11.9% +27.7% -81.7% +17.6%
Net Income Growth -7.7% +30.6% -88.7% +13.7%
EBITDA Growth -3.1% +36.7% -97.3% +15.8%
Insider Trading (Recent)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-06-29 EVNIN LUKE S-Sale 157,084.00 $0.30 $47,125
2026-06-17 RA CAPITAL MANAGEMENT, L.P. S-Sale 389,216.00 $0.35 $136,226
2026-06-17 RA CAPITAL MANAGEMENT, L.P. S-Sale 27,695.00 $0.35 $9,693
2026-06-12 RA CAPITAL MANAGEMENT, L.P. S-Sale 159,119.00 $0.40 $63,648
2026-06-15 RA CAPITAL MANAGEMENT, L.P. S-Sale 120,216.00 $0.39 $46,884
2026-06-16 RA CAPITAL MANAGEMENT, L.P. S-Sale 139,686.00 $0.37 $51,684
2026-06-12 RA CAPITAL MANAGEMENT, L.P. S-Sale 11,322.00 $0.40 $4,529
2026-06-15 RA CAPITAL MANAGEMENT, L.P. S-Sale 8,554.00 $0.39 $3,336
2026-06-16 RA CAPITAL MANAGEMENT, L.P. S-Sale 9,939.00 $0.37 $3,677
2026-06-09 RA CAPITAL MANAGEMENT, L.P. S-Sale 345,235.00 $0.37 $127,737
2026-06-10 RA CAPITAL MANAGEMENT, L.P. S-Sale 42,872.00 $0.37 $15,863
2026-06-11 RA CAPITAL MANAGEMENT, L.P. S-Sale 245,066.00 $0.38 $93,125
2026-06-09 RA CAPITAL MANAGEMENT, L.P. S-Sale 24,565.00 $0.37 $9,089
2026-06-10 RA CAPITAL MANAGEMENT, L.P. S-Sale 3,051.00 $0.37 $1,129
2026-06-11 RA CAPITAL MANAGEMENT, L.P. S-Sale 17,437.00 $0.38 $6,626
2026-06-09 EVNIN LUKE S-Sale 76,928.00 $0.37 $28,463
2026-06-04 EVNIN LUKE S-Sale 20,072.00 $0.44 $8,832
2026-06-05 EVNIN LUKE S-Sale 24,946.00 $0.40 $9,978
2026-06-08 EVNIN LUKE S-Sale 60,547.00 $0.40 $24,219
2026-06-01 EVNIN LUKE S-Sale 80,459.00 $0.47 $37,816
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for HOWL — it's generated by the pipeline (market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.360 · 7b6df9be · 2026-06-30 17:24:24