Business Description
Opus Genetics, Inc. is a clinical-stage biopharmaceutical company focused on ophthalmology. The company is dedicated to discovering and commercializing innovative therapies to address significant unmet medical needs in patients suffering from refractive and retinal eye disorders. Its portfolio includes Phentolamine Ophthalmic Solution, currently used to reverse pharmacologically induced mydriasis (pupil dilation). This solution is also advancing through Phase III clinical trials for the treatment of presbyopia and impaired vision in dim light or at night. A leading candidate in its retinal pipeline is APX3330, a small-molecule inhibitor targeting the reduction oxidation effector factor-1 protein. APX3330 has successfully completed Phase II clinical trials for diabetic retinopathy. Furthermore, Opus Genetics is developing APX2009 and APX2014, two preclinical product candidates also aimed at various retinal indications. Originally founded in 2018 as Ocuphire Pharma, Inc., the company maintains its headquarters in Farmington Hills, Michigan.
Business History
Price Overview
Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -0.80
Total Equity: $15.35M
Shares: 622,219,010
Total Debt: $0.00
Cash: $45.09M
EBITDA: -$48.07M
Total Debt: $0.00
Cash: $45.09M
Revenue: $14.20M
Shares: 622,219,010
Revenue: $14.20M
Revenue: $14.20M
Revenue: $14.20M
Total Equity: $15.35M
Tax Rate: 0.0%
Equity: $15.35M
Total Debt: $0.00
Cash: $45.09M
Current Liabilities: $7.78M
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $15.35M
Shares: 622,219,010
Shares: 622,219,010
CapEx: $0.00
Shares: 622,219,010
Stock Price: $4.23
Net Income: -$49.59M
Industry Benchmarks
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
Income Statement (Annual)
Last updated: Jul 5, 2026 4:04am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $589,000 | $39.9M | $19.0M | $11.0M | $14.2M |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $589,000 | $39.9M | $19.0M | $11.0M | $14.2M |
| Operating Expenses | $23.3M | $21.6M | $29.6M | $73.1M | $52.8M |
| Operating Income | -$22.7M | $18.2M | -$10.6M | -$62.1M | -$38.6M |
| Net Income | -$56.7M | $17.9M | -$10.0M | -$57.5M | -$49.6M |
| EBITDA | -$56.7M | $18.2M | -$10.0M | -$57.5M | -$48.1M |
| EPS | $-3.82 | $0.90 | $-0.46 | $-2.15 | $-0.80 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jul 5, 2026 4:04am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $24.5M | $42.6M | $50.5M | $30.3M | $45.1M |
| Total Current Assets | $26.1M | $49.0M | $53.9M | $36.6M | $50.0M |
| Total Assets | $26.1M | $49.0M | $53.9M | $36.9M | $50.2M |
| Current Liabilities | $3.9M | $2.8M | $4.0M | $11.3M | $7.8M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $3.9M | $2.8M | $4.0M | $30.1M | $34.9M |
| Total Equity | $22.2M | $46.2M | $49.9M | $6.7M | $15.3M |
| Retained Earnings | -$89.4M | -$71.5M | -$81.5M | -$139.0M | -$188.6M |
Cash Flow (Annual)
Last updated: Jul 5, 2026 4:04am (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$19.4M | $14.3M | -$1.1M | -$25.6M | -$35.3M |
| Capital Expenditure | $0 | $0 | $0 | $0 | $0 |
| Free Cash Flow | -$19.4M | $14.3M | -$1.1M | -$25.6M | -$35.3M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $-79,000 | $-152,000 |
| Net Change in Cash | $8.1M | $18.1M | $7.9M | -$20.2M | $14.8M |
Analyst Estimates (Annual)
Last updated: Jul 5, 2026 4:04am (just now)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$15.2M $1.9M – $31.0M
|
$47.5M $13.9M – $86.0M
|
$149.7M $44.0M – $271.3M
|
$313.7M $92.1M – $568.3M
|
| EBITDA |
-$9.3M -$19.0M – -$1.1M
|
-$29.1M -$52.7M – -$8.5M
|
-$91.8M -$166.3M – -$27.0M
|
-$192.4M -$348.5M – -$56.5M
|
| Net Income |
-$483.1M -$704.7M – -$261.4M
|
-$208.6M -$344.1M – -$73.2M
|
$565,597 $46,318 – $1.2M
|
$582.4M $47.7M – $1.2B
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jul 5, 2026 4:04am (just now)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | +6,665.7% | -52.2% | -42.3% | +29.1% |
| Gross Profit Growth | +6,665.7% | -52.2% | -42.3% | +29.1% |
| Operating Income Growth | +180.3% | -158.0% | -487.7% | +37.8% |
| Net Income Growth | +131.6% | -155.8% | -476.1% | +13.8% |
| EBITDA Growth | +132.1% | -154.7% | -477.1% | +16.4% |
Insider Trading (Recent)
All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-05-18 | Foundation Fighting Blindness Retinal Degeneration Fund | S-Sale | 1,700,000.00 | $4.35 | $7.4M |
| 2026-04-23 | YERXA BENJAMIN R | S-Sale | 7,470.00 | $5.24 | $39,121 |
| 2026-04-23 | SCHACHLE JOSEPH K | S-Sale | 4,697.00 | $5.22 | $24,519 |
| 2026-04-23 | Zaremba Rabourn Amy | S-Sale | 1,641.00 | $5.20 | $8,540 |
| 2026-04-23 | Magrath George | S-Sale | 9,511.00 | $5.22 | $49,647 |
| 2026-04-23 | Jayagopal Ashwath | S-Sale | 7,542.00 | $5.19 | $39,156 |
| 2026-04-23 | Gagnon Robert E. | S-Sale | 7,842.00 | $5.18 | $40,658 |
| 2026-04-20 | Rodgers Richard J | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | MANUSO JAMES S J | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | Graves Adrienne L | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | Gallagher Cam | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | Benton Susan | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | Bennett Jean | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-04-20 | Ainsworth Sean | A-Award | 24,367.00 | $0.00 | $0 |
| 2026-03-16 | SCHACHLE JOSEPH K | S-Sale | 3,719.00 | $5.25 | $19,525 |
| 2026-03-16 | Zaremba Rabourn Amy | S-Sale | 2,816.00 | $5.25 | $14,770 |
| 2026-03-16 | Magrath George | S-Sale | 24,438.00 | $5.21 | $127,327 |
| 2026-03-16 | Jayagopal Ashwath | S-Sale | 3,719.00 | $5.12 | $19,046 |
| 2026-02-12 | Jayagopal Ashwath | F-InKind | 5,313.00 | $3.39 | $18,011 |
| 2026-01-22 | YERXA BENJAMIN R | A-Award | 400,000.00 | $0.00 | $0 |
Narrative Economics
market-narrative step).