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Seres Therapeutics, Inc.

MCRB NASDAQ Categories PDF
Healthcare · Biotechnology
Cambridge, MA 02139, United States IPO 2015 serestherapeutics.com Updated Jul 5, 3:00am
Price
$7.74
Market Cap
$75.0M
Employees
103
Beta
0.10
Avg Volume
70,751
CEO
Richard N. Kender
Business Description

Seres Therapeutics, Inc. is a pioneering microbiome therapeutics firm dedicated to engineering bacterial consortia that modulate host cells and tissues to combat various diseases. Their flagship therapeutic, SER-109, an oral microbiome treatment, has successfully concluded Phase III clinical trials for the management of Clostridioides difficile infection (CDI). The company's pipeline further encompasses SER-155, a synthetically cultured bacterial formulation currently undergoing Phase Ib evaluation. This candidate aims to mitigate the risk of gastrointestinal and bloodstream infections, alongside graft-versus-host disease, in vulnerable patients undergoing allogeneic hematopoietic stem cell or solid organ transplantation. Additionally, Seres Therapeutics is advancing SER-287 and SER-301, both in Phase Ib for ulcerative colitis, as well as SER-401, which targets metastatic melanoma, and SER-262, also directed at Clostridioides difficile infection. Seres maintains strategic alliances through licensing and collaboration agreements with entities such as Nestec Ltd. and Memorial Sloan Kettering Cancer Center. Established in 2010, the company previously operated as Seres Health, Inc. before adopting its current name in May 2015, and it maintains its principal offices in Cambridge, Massachusetts.

Business History
Price Overview
Price at report time · Jul 5, 4:11am (0m ago)
$7.74
Change · Jul 5
-0.20 (-2.52%)
Day Range
$7.48 – $8.06
52-Week Range
$5.31 – $29.98
50-Day MA
$7.30
200-Day MA
$12.59
Volume
129,472.00
Right now · live
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Real-time — the change above is the move since the report (over 0m).
Analyst Price Targets
Low $12.00
Consensus $12.00
High $12.00
(2 analysts)
Share Structure
Outstanding 9,683,930.00
Float 7,339,489.00
Free Float 75.8%
Normal free float — 75.8% of shares trade freely, ~24.2% held by insiders/institutions
Healthy float typical of established companies. Good liquidity for entering and exiting positions without major price impact.
Small absolute float (7.3M shares) — even with a decent free float %, volume can be thin. Check average daily volume before sizing a position.
Price History (1 Year)
Last updated: Jul 5, 2026 4:11am (just now)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jul 5, 2026 4:11am (just now)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
12.09
Stock Price: $7.74
EPS (Diluted): 0.64
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
2.98
Stock Price: $7.74
Total Equity: $44.22M
Shares: 8,869,742
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-3.00
Market Cap: $74.95M
Total Debt: $10.39M
Cash: $45.77M
EBITDA: $9.83M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$169.0M
Market Cap: $74.95M
Total Debt: $10.39M
Cash: $45.77M
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
-423.8%
Gross Profit: -$3.34M
Revenue: $789,000
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
-11,910.1%
Operating Income: -$93.97M
Revenue: $789,000
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
721.9%
Net Income: $5.70M
Revenue: $789,000
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-127.3%
Net Income: $5.70M
Total Equity: $44.22M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-80.3%
Operating Income: -$93.97M
Tax Rate: 0.0%
Equity: $44.22M
Total Debt: $10.39M
Cash: $45.77M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
2.56
Current Assets: $49.38M
Current Liabilities: $19.32M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.23
Short-Term Debt: $10.39M
Long-Term Debt: $0.00
Total Debt: $10.39M
Total Equity: $44.22M
Rev/Share (Top-line per share)
CALC
Revenue / Shares Outstanding
$0.09
Revenue: $789,000
Shares: 8,869,742
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$4.99
Total Equity: $44.22M
Shares: 8,869,742
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$0.10
Operating CF: $1.12M
CapEx: -$252,000
Shares: 8,869,742
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $7.74
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: $5.70M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares MCRB against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jul 5, 2026 4:11am (just now)
Metric 2021 2022 2023 2024 2025
Revenue $144.9M $0 $0 $0 $789,000
Cost of Revenue $0 $0 $19.3M $3.5M $4.1M
Gross Profit $144.9M $0 -$19.3M -$3.5M -$3.3M
Operating Expenses $209.4M $179.9M $175.8M $117.8M $90.6M
Operating Income -$64.5M -$179.9M -$195.1M -$121.3M -$94.0M
Net Income -$65.6M -$250.2M -$113.7M -$146.6M $5.7M
EBITDA -$56.7M -$170.9M -$181.4M -$120.3M $9.8M
EPS $-14.30 $-46.29 $-17.77 $-18.86 $0.64
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jul 5, 2026 4:11am (just now)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $180.0M $163.0M $128.0M $30.8M $45.8M
Total Current Assets $303.6M $194.8M $175.4M $38.7M $49.4M
Total Assets $354.9M $348.8M $358.6M $139.8M $138.2M
Current Liabilities $82.3M $85.6M $98.7M $41.2M $19.3M
Long-Term Debt $24.6M $50.6M $101.5M $0 $0
Total Liabilities $223.4M $338.0M $403.5M $126.0M $94.0M
Total Equity $131.5M $10.8M -$44.9M $13.8M $44.2M
Retained Earnings -$614.4M -$864.5M -$978.2M -$978.1M -$972.4M
Cash Flow (Annual)
Last updated: Jul 5, 2026 4:11am (just now)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow $6.7M -$228.8M -$117.4M -$148.6M $1.1M
Capital Expenditure -$9.6M -$9.8M -$8.0M $-380,000 $-252,000
Free Cash Flow -$2.9M -$238.6M -$125.3M -$149.0M $865,000
Acquisitions (net) $0 -$92.2M $0 $0 $210,000
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $72.0M -$16.8M -$35.1M -$96.7M $15.0M
Analyst Estimates (Annual)
Last updated: Jul 5, 2026 4:11am (just now)
Metric 2026 2027 2028 2029
Revenue $12.9M
$8.7M – $17.0M
$358,000
$243,180 – $472,819
$358,000
$243,180 – $472,819
$249,644
$169,576 – $329,711
EBITDA $9.3M
$6.3M – $12.3M
$258,377
$175,509 – $341,245
$258,377
$175,509 – $341,245
$180,174
$122,387 – $237,960
Net Income -$81.4M
-$94.4M – -$38.9M
-$58.3M
-$82.6M – -$34.0M
-$103.1M
-$143.4M – -$59.0M
-$78.1M
-$110.6M – -$45.5M
EPS
Growth Trends (YoY %)
Last updated: Jul 5, 2026 4:11am (just now)
Metric 2022 2023 2024 2025
Revenue Growth -100.0%
Gross Profit Growth -100.0% +81.7% +5.3%
Operating Income Growth -179.0% -8.4% +37.8% +22.5%
Net Income Growth -281.5% +54.5% -28.9% +103.9%
EBITDA Growth -201.4% -6.1% +33.7% +108.2%
Insider Trading (Recent)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-07-01 Berenson Stephen A-Award 7,508.00 $7.94 $59,614
2026-07-01 Rosiello Robert L. A-Award 7,508.00 $7.94 $59,614
2026-07-01 Ausiello Dennis A A-Award 7,508.00 $7.94 $59,614
2026-05-15 Shaff Eric D. M-Exempt 722.00 $0.00 $0
2026-05-18 Shaff Eric D. S-Sale 259.00 $7.53 $1,950
2026-05-15 DesRosier Thomas M-Exempt 244.00 $0.00 $0
2026-05-18 DesRosier Thomas S-Sale 79.00 $7.53 $595
2026-05-15 Shaff Eric D. M-Exempt 331.00 $0.00 $0
2026-05-15 Shaff Eric D. M-Exempt 391.00 $0.00 $0
2026-05-15 DesRosier Thomas M-Exempt 111.00 $0.00 $0
2026-05-15 DesRosier Thomas M-Exempt 133.00 $0.00 $0
2026-05-15 Brady Kelly M-Exempt 180.00 $0.00 $0
2026-05-18 Brady Kelly S-Sale 59.00 $7.53 $444
2026-05-15 Henn Matthew R M-Exempt 238.00 $0.00 $0
2026-05-18 Henn Matthew R S-Sale 77.00 $7.53 $580
2026-05-15 Henn Matthew R M-Exempt 97.00 $0.00 $0
2026-05-15 Brady Kelly M-Exempt 91.00 $0.00 $0
2026-05-15 Henn Matthew R M-Exempt 141.00 $0.00 $0
2026-05-15 Brady Kelly M-Exempt 89.00 $0.00 $0
2026-03-04 Brady Kelly A-Award 56,250.00 $9.13 $513,563
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for MCRB — it's generated by the pipeline (market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.377 · 1648bd22 · 2026-07-04 14:36:23