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Protagenic Therapeutics, Inc.

PTIX NASDAQ Categories PDF
Healthcare · Biotechnology · United States · Updated May 11, 10:15am
$0.82
Price
$1.5M
Market Cap
1
Employees
0.47
Beta
Garo H. Armen
CEO
Business Description

Protagenic Therapeutics, Inc., a biopharmaceutical company, engages in the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. Its lead compound is PT00114, a synthetic form of teneurin carboxy-terminal associated peptide, an endogenous brain signaling peptide that can dampen overactive stress responses. The company is based in New York, New York.

Business History
Price History (1 Year)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-0.24
Stock Price: $0.82
EPS (Diluted): -3.45
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
-1.05
Stock Price: $0.82
Total Equity: -$2.39M
Shares: 1,934,878
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-0.30
Market Cap: $1.48M
Total Debt: $3.16M
Cash: $2.21M
EBITDA: -$8.02M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$3.5M
Market Cap: $1.48M
Total Debt: $3.16M
Cash: $2.21M
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
0.0%
Gross Profit: -$37,715
Revenue: $0.00
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
0.0%
Operating Income: -$5.83M
Revenue: $0.00
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
0.0%
Net Income: -$5.16M
Revenue: $0.00
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
184.9%
Net Income: -$5.16M
Total Equity: -$2.39M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
379.7%
Operating Income: -$5.83M
Tax Rate: 0.0%
Equity: -$2.39M
Total Debt: $3.16M
Cash: $2.21M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
0.34
Current Assets: $2.30M
Current Liabilities: $6.82M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
-1.32
Short-Term Debt: $3.16M
Long-Term Debt: $0.00
Total Debt: $3.16M
Total Equity: -$2.39M
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
—
Revenue: $0.00
Shares: 1,934,878
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$-1.24
Total Equity: -$2.39M
Shares: 1,934,878
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-2.14
Operating CF: -$4.14M
CapEx: -$3.00
Shares: 1,934,878
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $0.82
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
—
Dividends Paid: N/A
Net Income: -$5.16M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares PTIX against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Metric 2021 2022 2023 2024 2025
Revenue $0 $0 $0 $0 $0
Cost of Revenue $0 $30 $28,218 $50,286 $37,715
Gross Profit $0 $-30 $-28,218 $-50,286 $-37,715
Operating Expenses $4.1M $3.6M $4.5M $5.7M $5.8M
Operating Income -$4.1M -$3.6M -$4.5M -$5.7M -$5.8M
Net Income -$4.5M -$3.6M -$5.0M -$5.5M -$5.2M
EBITDA -$4.1M -$3.4M -$4.5M -$5.5M -$8.0M
EPS $-1.24 $-0.82 $-1.15 $-1.13 $-3.45
EPS (Diluted) — — — — —
Balance Sheet (Annual)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $541,171 $215,189 $1.3M $1.8M $2.2M
Total Current Assets $11.1M $8.0M $4.2M $1.9M $2.3M
Total Assets $11.1M $8.0M $4.3M $2.0M $2.1M
Current Liabilities $799,535 $1.1M $655,252 $942,759 $6.8M
Long-Term Debt $318,433 $0 $0 $0 $0
Total Liabilities $1.1M $1.1M $655,252 $942,759 $6.8M
Total Equity $9.9M $6.9M $3.7M $1.0M -$2.4M
Retained Earnings -$22.2M -$25.8M -$30.8M -$36.3M -$9.1M
Cash Flow (Annual)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$2.8M -$2.0M -$3.7M -$4.2M -$4.1M
Capital Expenditure $4 $-1,805 $-149,775 $0 $-3
Free Cash Flow -$2.8M -$2.0M -$3.9M -$4.2M -$4.1M
Acquisitions (net) $0 $46,051 $0 $0 $0
Debt Repayment — — — — —
Dividends Paid — — — — —
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $-129,920 $-325,982 $1.1M $550,576 $4.5M
Analyst Estimates (Annual)
Metric 2024 2025
Revenue $0 $0
EBITDA $0 $0
Net Income -$167.4M
-$167.4M – -$167.4M
 -$68.3M
-$68.3M – -$68.3M
EPS — —
Growth Trends (YoY %)
Metric 2022 2023 2024 2025
Revenue Growth — — — —
Gross Profit Growth — -93,960.0% -78.2% +25.0%
Operating Income Growth +14.1% -27.2% -25.9% -2.3%
Net Income Growth +21.4% -40.6% -10.5% +6.7%
EBITDA Growth +17.4% -31.6% -21.7% -46.6%
Insider Trading (Recent)
Date Insider Type Shares Price Value
2025-05-15 EVANS BARRETT 0.00 $0.00 $0
2025-05-15 EVANS BARRETT 0.00 $0.00 $0
2025-05-15 EVANS BARRETT 0.00 $0.00 $0
2025-05-15 EVANS BARRETT 0.00 $0.00 $0
2025-05-15 EVANS BARRETT 0.00 $0.00 $0
2024-03-25 WRIGHT TIMOTHY R A-Award 21,250.00 $1.74 $36,975
2024-03-25 Stein Robert Benjamin A-Award 75,000.00 $1.74 $130,500
2024-03-25 Barrage Khalil A-Award 22,500.00 $1.74 $39,150
2024-03-25 Buell Jennifer A-Award 75,000.00 $1.74 $130,500
2024-03-25 ARMEN GARO H A-Award 250,000.00 $1.74 $435,000
2024-03-25 Corvese Brian A-Award 43,750.00 $1.74 $76,125
2024-03-25 Arrow Alexander K. A-Award 100,000.00 $1.74 $174,000
2023-10-12 Arrow Alexander K. P-Purchase 8,000.00 $0.81 $6,480
2022-05-17 Arrow Alexander K. P-Purchase 8,000.00 $0.72 $5,760
2022-05-17 Arrow Alexander K. P-Purchase 23,000.00 $0.71 $16,330
2021-06-03 Arrow Alexander K. P-Purchase 16,900.00 $4.98 $84,162
2021-06-02 Arrow Alexander K. P-Purchase 100.00 $4.98 $498
2021-05-26 Barrage Khalil A-Award 180,000.00 $3.65 $657,000
2021-05-27 Arrow Alexander K. P-Purchase 3,000.00 $4.98 $14,940
2021-05-18 Arrow Alexander K. P-Purchase 18,000.00 $4.98 $89,640
Dividend History (Last 20)
Date Dividend Declaration Record Payment
2005-12-05 $0.46 2005-10-31
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.193 · 1946f027 · 2026-05-08 18:57:27