Business Description
Rein Therapeutics Inc. operates as a clinical-stage biopharmaceutical enterprise focused on discovering and bringing to market novel therapeutic solutions for various conditions, notably cancer. The company's leading drug candidate, ALRN-6924, is a distinctive cell-penetrating peptide. This compound works by disrupting the harmful interaction between the p53 suppressor proteins, MDM2 and MDMX, and the vital p53 tumor suppressor. Its goal is to reactivate the natural tumor-suppressing pathways in cancers where the p53 gene is still functional, or "wild-type." The organization was founded on August 6, 2001, by Gregory L. Verdine, Rosana Kapeller, Huw M. Nash, Joseph A. Yanchik III, and Loren David Walensky, and its main corporate offices are situated in Austin, Texas.
Business History
Price Overview
Last updated: Jun 27, 2026 10:09am (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -1.96
Total Equity: $16.92M
Shares: 25,444,795
Total Debt: $0.00
Cash: $3.22M
EBITDA: -$50.58M
Total Debt: $0.00
Cash: $3.22M
Revenue: $0.00
Shares: 25,444,795
Revenue: $0.00
Revenue: $0.00
Revenue: $0.00
Total Equity: $16.92M
Tax Rate: 1.4%
Equity: $16.92M
Total Debt: $0.00
Cash: $3.22M
Current Liabilities: $6.18M
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $16.92M
Shares: 25,444,795
Shares: 25,444,795
CapEx: $0.00
Shares: 25,444,795
Stock Price: $0.97
Net Income: -$49.87M
Industry Benchmarks
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
Income Statement (Annual)
Last updated: Jun 20, 2026 12:06pm (6d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 |
| Cost of Revenue | $0 | $0 | $0 | $0 | $1,000 |
| Gross Profit | $0 | $0 | $0 | $0 | $-1,000 |
| Operating Expenses | $26,605 | $27,647 | $16,276 | $65.1M | $21.9M |
| Operating Income | $-26,605 | $-27,647 | $-16,276 | -$65.1M | -$21.9M |
| Net Income | $-26,164 | $-27,329 | $-15,732 | -$62.9M | -$49.9M |
| EBITDA | $-26,043 | $-27,160 | $-15,229 | -$28.0M | -$50.6M |
| EPS | $-5.89 | $-6.02 | $-3.42 | $-3.51 | $-1.96 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 26, 2026 4:11pm (17h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $3.6M | $5.2M | $17.3M | $12.9M | $3.2M |
| Total Current Assets | $48.2M | $21.9M | $18.3M | $13.7M | $4.3M |
| Total Assets | $48.5M | $22.0M | $106.0M | $69.2M | $24.2M |
| Current Liabilities | $4.5M | $3.4M | $4.4M | $5.7M | $6.2M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $4.6M | $3.4M | $99.1M | $14.8M | $7.2M |
| Total Equity | $43.9M | $18.6M | $6.9M | $54.4M | $16.9M |
| Retained Earnings | -$245.5M | -$272.8M | -$288.5M | -$351.4M | -$401.3M |
Cash Flow (Annual)
Last updated: Jun 26, 2026 4:11pm (17h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$23.8M | -$24.9M | -$19.8M | -$22.3M | -$19.4M |
| Capital Expenditure | $-157,000 | $0 | $0 | $0 | $0 |
| Free Cash Flow | -$23.9M | -$24.9M | -$19.8M | -$22.3M | -$19.4M |
| Acquisitions (net) | $0 | $0 | $-96,000 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$4.0M | $1.6M | $12.1M | -$4.5M | -$9.7M |
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 4:11pm (17h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$127.7M $127.7M – $127.7M
|
$0 | $0 |
$144.1M $144.1M – $144.1M
|
| EBITDA | $0 | $0 | $0 | $0 |
| Net Income |
-$12.7M -$12.7M – -$12.7M
|
-$16.8M -$16.8M – -$16.8M
|
-$14.5M -$14.5M – -$14.5M
|
$14.0M $14.0M – $14.0M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 20, 2026 12:06pm (6d ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | — | — | — |
| Gross Profit Growth | — | — | — | — |
| Operating Income Growth | -3.9% | +41.1% | -399,949.2% | +66.3% |
| Net Income Growth | -4.5% | +42.4% | -399,614.0% | +20.7% |
| EBITDA Growth | -4.3% | +43.9% | -184,081.5% | -80.3% |
Insider Trading (Recent)
All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-05-27 | VON RICKENBACH JOSEF H | P-Purchase | 4,500.00 | $1.07 | $4,819 |
| 2026-05-26 | VON RICKENBACH JOSEF H | P-Purchase | 23,190.00 | $1.06 | $24,470 |
| 2026-05-22 | VON RICKENBACH JOSEF H | P-Purchase | 15,950.00 | $1.05 | $16,708 |
| 2026-05-21 | VON RICKENBACH JOSEF H | P-Purchase | 3,420.00 | $1.04 | $3,564 |
| 2026-05-08 | WINDSOR JAMES BRIAN | A-Award | 150,000.00 | $1.17 | $175,500 |
| 2026-04-30 | WINDSOR JAMES BRIAN | P-Purchase | 25,000.00 | $1.00 | $25,000 |
| 2025-11-14 | Voss Capital, LP | P-Purchase | 104,183.00 | $1.22 | $127,593 |
| 2025-10-27 | Voss Capital, LP | P-Purchase | 92,642.00 | $1.37 | $126,920 |
| 2025-10-24 | Voss Capital, LP | P-Purchase | 30,176.00 | $1.39 | $41,957 |
| 2025-10-28 | Voss Capital, LP | P-Purchase | 178,392.00 | $1.39 | $247,965 |
| 2025-10-27 | Voss Capital, LP | P-Purchase | 4,840.00 | $1.37 | $6,625 |
| 2025-09-24 | Voss Capital, LP | 0.00 | $0.00 | $0 | |
| 2025-09-24 | Voss Capital, LP | 0.00 | $0.00 | $0 | |
| 2025-07-23 | Aivado Manuel | A-Award | 17,500.00 | $1.55 | $27,125 |
| 2025-07-23 | VON RICKENBACH JOSEF H | A-Award | 17,500.00 | $1.55 | $27,125 |
| 2025-07-23 | Musso Alan A | A-Award | 17,500.00 | $1.55 | $27,125 |
| 2025-07-23 | Fairey William | A-Award | 17,500.00 | $1.55 | $27,125 |
| 2025-07-23 | Ambros Reinhard J. | A-Award | 17,500.00 | $1.55 | $27,125 |
Narrative Economics
market-narrative step).