Business Description
Tango Therapeutics, Inc. is a biotechnology firm dedicated to the research and development of innovative cancer treatments. Their primary therapeutic candidate, TNG908, is a synthetic lethal small molecule designed to inhibit protein arginine methyltransferase 5 (PRMT5). This compound is currently being advanced as a potential therapy for cancers characterized by methylthioadenosine phosphorylase (MTAP) deletions. Additionally, their pipeline includes an Ubiquitin-specific protease 1 (USP1) inhibitor targeting BRCA1 or BRCA2-mutant cancers, and a program known as 'Target 3' which addresses STK11-mutant cancers. Tango Therapeutics maintains a strategic alliance with Gilead Sciences, Inc., focused on the identification, advancement, and commercialization of a diverse array of cancer therapies. Established in 2017, the company's operations are headquartered in Cambridge, Massachusetts.
Business History
Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -0.87
Total Equity: $346.18M
Shares: 116,166,187
Total Debt: $30.83M
Cash: $112.28M
EBITDA: -$99.31M
Total Debt: $30.83M
Cash: $112.28M
Revenue: $62.38M
Shares: 116,166,187
Revenue: $62.38M
Revenue: $62.38M
Revenue: $62.38M
Total Equity: $346.18M
Tax Rate: 0.0%
Equity: $346.18M
Total Debt: $30.83M
Cash: $112.28M
Current Liabilities: $21.68M
Long-Term Debt: $30.83M
Total Debt: $30.83M
Total Equity: $346.18M
Shares: 116,166,187
Shares: 116,166,187
CapEx: -$1.05M
Shares: 116,166,187
Stock Price: $31.47
Net Income: -$101.59M
Industry Benchmarks
Deep Analysis
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Income Statement (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $37.0M | $24.9M | $36.5M | $42.1M | $62.4M |
| Cost of Revenue | $0 | $0 | $0 | $0 | $2.3M |
| Gross Profit | $37.0M | $24.9M | $36.5M | $42.1M | $60.1M |
| Operating Expenses | $95.2M | $135.9M | $150.7M | $187.7M | $171.4M |
| Operating Income | -$58.2M | -$111.1M | -$114.2M | -$145.6M | -$111.3M |
| Net Income | -$58.2M | -$108.2M | -$101.7M | -$130.3M | -$101.6M |
| EBITDA | -$57.0M | -$106.5M | -$99.2M | -$127.6M | -$99.3M |
| EPS | $-0.94 | $-1.23 | $-1.08 | $-1.19 | $-0.87 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $142.7M | $60.0M | $66.4M | $69.5M | $112.3M |
| Total Current Assets | $492.3M | $375.3M | $346.5M | $266.3M | $353.8M |
| Total Assets | $500.2M | $436.5M | $402.6M | $316.5M | $398.7M |
| Current Liabilities | $40.7M | $55.5M | $45.9M | $38.2M | $21.7M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $30.8M |
| Total Liabilities | $155.4M | $187.0M | $149.5M | $117.0M | $52.5M |
| Total Equity | $344.7M | $249.5M | $253.1M | $199.5M | $346.2M |
| Retained Earnings | -$161.3M | -$269.5M | -$371.3M | -$501.6M | -$603.2M |
Cash Flow (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$59.5M | -$109.1M | -$118.0M | -$131.5M | -$138.9M |
| Capital Expenditure | -$1.8M | -$7.7M | -$1.5M | $-754,000 | -$1.0M |
| Free Cash Flow | -$61.4M | -$116.8M | -$119.5M | -$132.3M | -$139.9M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $114.4M | -$81.1M | $5.9M | $2.3M | $42.7M |
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$3.9M $3.9M – $3.9M
|
$63.7M $63.7M – $63.7M
|
$255.9M $255.9M – $255.9M
|
$658.7M $658.7M – $658.7M
|
| EBITDA |
-$3.9M -$3.9M – -$3.9M
|
-$63.7M -$63.7M – -$63.7M
|
-$255.9M -$255.9M – -$255.9M
|
-$658.7M -$658.7M – -$658.7M
|
| Net Income |
-$171.6M -$205.2M – -$138.0M
|
-$173.1M -$219.6M – -$126.6M
|
-$110.5M -$110.5M – -$110.5M
|
$102.9M $102.9M – $102.9M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 26, 2026 11:00pm (11h ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | -32.9% | +46.9% | +15.2% | +48.3% |
| Gross Profit Growth | -32.9% | +46.9% | +15.2% | +42.9% |
| Operating Income Growth | -90.9% | -2.8% | -27.5% | +23.6% |
| Net Income Growth | -85.8% | +5.9% | -28.1% | +22.0% |
| EBITDA Growth | -86.7% | +6.9% | -28.6% | +22.2% |
Insider Trading (Recent)
Last updated: Jun 27, 2026 6:32am (3h ago)All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-19 | Azelby Robert | A-Award | 35,910.00 | $27.97 | $1.0M |
| 2026-06-19 | Azelby Robert | A-Award | 5,740.00 | $0.00 | $0 |
| 2026-06-19 | Azelby Robert | 0.00 | $0.00 | $0 | |
| 2026-06-05 | Ketchum John B | A-Award | 25,000.00 | $20.22 | $505,500 |
| 2026-06-05 | Ketchum John B | A-Award | 4,000.00 | $0.00 | $0 |
| 2026-06-05 | Calhoun Lesley Ann | A-Award | 25,000.00 | $20.22 | $505,500 |
| 2026-06-05 | Calhoun Lesley Ann | A-Award | 4,000.00 | $0.00 | $0 |
| 2026-06-05 | Rothenberg Mace | A-Award | 4,000.00 | $0.00 | $0 |
| 2026-06-05 | Rothenberg Mace | A-Award | 25,000.00 | $20.22 | $505,500 |
| 2026-06-05 | Lee Sung | A-Award | 570.00 | $0.00 | $0 |
| 2026-06-05 | Lee Sung | A-Award | 3,570.00 | $20.22 | $72,185 |
| 2026-06-01 | Crystal Adam | M-Exempt | 27,000.00 | $5.20 | $140,400 |
| 2026-06-01 | Crystal Adam | M-Exempt | 27,000.00 | $5.20 | $140,400 |
| 2026-06-01 | Crystal Adam | S-Sale | 6,140.00 | $22.25 | $136,627 |
| 2026-06-01 | Crystal Adam | S-Sale | 20,860.00 | $23.06 | $480,944 |
| 2026-05-01 | Crystal Adam | M-Exempt | 27,000.00 | $5.20 | $140,400 |
| 2026-05-01 | Crystal Adam | M-Exempt | 27,000.00 | $5.20 | $140,400 |
| 2026-05-01 | Crystal Adam | S-Sale | 25,900.00 | $21.19 | $548,901 |
| 2026-05-01 | Crystal Adam | S-Sale | 1,100.00 | $22.00 | $24,196 |
| 2026-05-01 | Gall Matthew | A-Award | 240,000.00 | $20.98 | $5.0M |
Narrative Economics
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