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Tango Therapeutics, Inc.

TNGX NASDAQ Categories PDF
Healthcare · Biotechnology
Boston, MA 02142, United States IPO 2020 tangotx.com Updated Jun 26, 11:00pm
Price
$31.47
Market Cap
$3.9B
Employees
155
Beta
1.19
Avg Volume
3,864,396
CEO
Malte Peters
Business Description

Tango Therapeutics, Inc. is a biotechnology firm dedicated to the research and development of innovative cancer treatments. Their primary therapeutic candidate, TNG908, is a synthetic lethal small molecule designed to inhibit protein arginine methyltransferase 5 (PRMT5). This compound is currently being advanced as a potential therapy for cancers characterized by methylthioadenosine phosphorylase (MTAP) deletions. Additionally, their pipeline includes an Ubiquitin-specific protease 1 (USP1) inhibitor targeting BRCA1 or BRCA2-mutant cancers, and a program known as 'Target 3' which addresses STK11-mutant cancers. Tango Therapeutics maintains a strategic alliance with Gilead Sciences, Inc., focused on the identification, advancement, and commercialization of a diverse array of cancer therapies. Established in 2017, the company's operations are headquartered in Cambridge, Massachusetts.

Business History
Price History (1 Year)
Last updated: Jun 27, 2026 6:32am (3h ago)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jun 26, 2026 11:00pm (11h ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-36.17
Stock Price: $31.47
EPS (Diluted): -0.87
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
2.97
Stock Price: $31.47
Total Equity: $346.18M
Shares: 116,166,187
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-36.06
Market Cap: $3.92B
Total Debt: $30.83M
Cash: $112.28M
EBITDA: -$99.31M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$950.5M
Market Cap: $3.92B
Total Debt: $30.83M
Cash: $112.28M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
16.50
Stock Price: $31.47
Revenue: $62.38M
Shares: 116,166,187
EV/Sales (Total value vs revenue — works when P/E can't)
API
15.24
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
96.3%
Gross Profit: $60.10M
Revenue: $62.38M
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
-178.4%
Operating Income: -$111.29M
Revenue: $62.38M
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
-162.9%
Net Income: -$101.59M
Revenue: $62.38M
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-41.5%
Net Income: -$101.59M
Total Equity: $346.18M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-27.7%
Operating Income: -$111.29M
Tax Rate: 0.0%
Equity: $346.18M
Total Debt: $30.83M
Cash: $112.28M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
16.32
Current Assets: $353.76M
Current Liabilities: $21.68M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.09
Short-Term Debt: $0.00
Long-Term Debt: $30.83M
Total Debt: $30.83M
Total Equity: $346.18M
Rev/Share (Top-line per share)
CALC
Revenue / Shares Outstanding
$0.54
Revenue: $62.38M
Shares: 116,166,187
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$2.98
Total Equity: $346.18M
Shares: 116,166,187
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-1.20
Operating CF: -$138.89M
CapEx: -$1.05M
Shares: 116,166,187
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $31.47
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$101.59M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares TNGX against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)
Metric 2021 2022 2023 2024 2025
Revenue $37.0M $24.9M $36.5M $42.1M $62.4M
Cost of Revenue $0 $0 $0 $0 $2.3M
Gross Profit $37.0M $24.9M $36.5M $42.1M $60.1M
Operating Expenses $95.2M $135.9M $150.7M $187.7M $171.4M
Operating Income -$58.2M -$111.1M -$114.2M -$145.6M -$111.3M
Net Income -$58.2M -$108.2M -$101.7M -$130.3M -$101.6M
EBITDA -$57.0M -$106.5M -$99.2M -$127.6M -$99.3M
EPS $-0.94 $-1.23 $-1.08 $-1.19 $-0.87
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $142.7M $60.0M $66.4M $69.5M $112.3M
Total Current Assets $492.3M $375.3M $346.5M $266.3M $353.8M
Total Assets $500.2M $436.5M $402.6M $316.5M $398.7M
Current Liabilities $40.7M $55.5M $45.9M $38.2M $21.7M
Long-Term Debt $0 $0 $0 $0 $30.8M
Total Liabilities $155.4M $187.0M $149.5M $117.0M $52.5M
Total Equity $344.7M $249.5M $253.1M $199.5M $346.2M
Retained Earnings -$161.3M -$269.5M -$371.3M -$501.6M -$603.2M
Cash Flow (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$59.5M -$109.1M -$118.0M -$131.5M -$138.9M
Capital Expenditure -$1.8M -$7.7M -$1.5M $-754,000 -$1.0M
Free Cash Flow -$61.4M -$116.8M -$119.5M -$132.3M -$139.9M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $114.4M -$81.1M $5.9M $2.3M $42.7M
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 11:00pm (11h ago)
Metric 2027 2028 2029 2030
Revenue $3.9M
$3.9M – $3.9M
$63.7M
$63.7M – $63.7M
$255.9M
$255.9M – $255.9M
$658.7M
$658.7M – $658.7M
EBITDA -$3.9M
-$3.9M – -$3.9M
-$63.7M
-$63.7M – -$63.7M
-$255.9M
-$255.9M – -$255.9M
-$658.7M
-$658.7M – -$658.7M
Net Income -$171.6M
-$205.2M – -$138.0M
-$173.1M
-$219.6M – -$126.6M
-$110.5M
-$110.5M – -$110.5M
$102.9M
$102.9M – $102.9M
EPS
Growth Trends (YoY %)
Last updated: Jun 26, 2026 11:00pm (11h ago)
Metric 2022 2023 2024 2025
Revenue Growth -32.9% +46.9% +15.2% +48.3%
Gross Profit Growth -32.9% +46.9% +15.2% +42.9%
Operating Income Growth -90.9% -2.8% -27.5% +23.6%
Net Income Growth -85.8% +5.9% -28.1% +22.0%
EBITDA Growth -86.7% +6.9% -28.6% +22.2%
Insider Trading (Recent)
Last updated: Jun 27, 2026 6:32am (3h ago)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-06-19 Azelby Robert A-Award 35,910.00 $27.97 $1.0M
2026-06-19 Azelby Robert A-Award 5,740.00 $0.00 $0
2026-06-19 Azelby Robert 0.00 $0.00 $0
2026-06-05 Ketchum John B A-Award 25,000.00 $20.22 $505,500
2026-06-05 Ketchum John B A-Award 4,000.00 $0.00 $0
2026-06-05 Calhoun Lesley Ann A-Award 25,000.00 $20.22 $505,500
2026-06-05 Calhoun Lesley Ann A-Award 4,000.00 $0.00 $0
2026-06-05 Rothenberg Mace A-Award 4,000.00 $0.00 $0
2026-06-05 Rothenberg Mace A-Award 25,000.00 $20.22 $505,500
2026-06-05 Lee Sung A-Award 570.00 $0.00 $0
2026-06-05 Lee Sung A-Award 3,570.00 $20.22 $72,185
2026-06-01 Crystal Adam M-Exempt 27,000.00 $5.20 $140,400
2026-06-01 Crystal Adam M-Exempt 27,000.00 $5.20 $140,400
2026-06-01 Crystal Adam S-Sale 6,140.00 $22.25 $136,627
2026-06-01 Crystal Adam S-Sale 20,860.00 $23.06 $480,944
2026-05-01 Crystal Adam M-Exempt 27,000.00 $5.20 $140,400
2026-05-01 Crystal Adam M-Exempt 27,000.00 $5.20 $140,400
2026-05-01 Crystal Adam S-Sale 25,900.00 $21.19 $548,901
2026-05-01 Crystal Adam S-Sale 1,100.00 $22.00 $24,196
2026-05-01 Gall Matthew A-Award 240,000.00 $20.98 $5.0M
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for TNGX — it's generated by the pipeline (market-narrative step).
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My Notes personal — only you see this
Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30