Business Description
Tvardi Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of novel, oral, and small molecule therapies targeting signal transducer and activator of transcription 3 (STAT3) to treat inflammatory and proliferative diseases with significant unmet need in the United States. The company's lead product candidates include TTI-101, which is in Phase 1b/2 clinical development stage for fibrosis-driven diseases with an initial focus on idiopathic pulmonary fibrosis (IPF), and hepatocellular carcinoma (HCC); and TTI-109, an oral, small molecule STAT3 inhibitor which is in Phase-1 clinical trial stage. Tvardi Therapeutics, Inc. was founded in 2017 and is based in Sugar Land, Texas.
Business History
Price Overview
Last updated: Jun 27, 2026 8:03am (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -2.46
Total Equity: $20.95M
Shares: 7,783,182
Total Debt: $0.00
Cash: $20.73M
EBITDA: -$18.12M
Total Debt: $0.00
Cash: $20.73M
Revenue: $0.00
Shares: 7,783,182
Revenue: $0.00
Revenue: $0.00
Revenue: $0.00
Total Equity: $20.95M
Tax Rate: 0.0%
Equity: $20.95M
Total Debt: $0.00
Cash: $20.73M
Current Liabilities: $11.04M
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $20.95M
Shares: 7,783,182
Shares: 7,783,182
CapEx: $0.00
Shares: 7,783,182
Stock Price: $1.50
Net Income: -$18.21M
Industry Benchmarks
Deep Analysis
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Income Statement (Annual)
Last updated: Jun 26, 2026 11:40pm (8h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $23.0M | $41.9M | $21.0M | $7.1M | $0 |
| Cost of Revenue | $1.6M | $7.5M | $6.4M | $812,000 | $95,000 |
| Gross Profit | $21.5M | $34.4M | $14.5M | $6.3M | $-95,000 |
| Operating Expenses | $110.6M | $121.9M | $136.0M | $62.1M | $26.7M |
| Operating Income | -$89.1M | -$87.5M | -$121.5M | -$55.8M | -$26.7M |
| Net Income | -$88.4M | -$85.5M | -$118.5M | -$70.9M | -$18.2M |
| EBITDA | -$86.9M | -$83.8M | -$117.7M | -$62.6M | -$18.1M |
| EPS | $-62.77 | $-2.20 | $-1.85 | $-46.59 | $-2.46 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 26, 2026 11:40pm (8h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $13.5M | $21.5M | $22.9M | $37.9M | $20.7M |
| Total Current Assets | $173.3M | $44.1M | $26.2M | $43.8M | $31.5M |
| Total Assets | $247.1M | $45.1M | $27.0M | $43.8M | $32.1M |
| Current Liabilities | $17.6M | $4.3M | $3.3M | $4.0M | $11.0M |
| Long-Term Debt | $0 | $0 | $0 | $44.4M | $0 |
| Total Liabilities | $19.5M | $90.1M | $89.1M | $48.4M | $11.1M |
| Total Equity | $227.5M | -$45.1M | -$62.1M | -$4.6M | $20.9M |
| Retained Earnings | -$480.8M | -$45.5M | -$62.8M | -$755.6M | -$110.5M |
Cash Flow (Annual)
Last updated: Jun 26, 2026 11:40pm (8h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$60.1M | -$17.9M | -$21.0M | -$60.9M | -$23.5M |
| Capital Expenditure | $-39,000 | $-50,000 | -$2.4M | -$1.0M | $0 |
| Free Cash Flow | -$60.1M | -$17.9M | -$21.0M | -$62.0M | -$23.5M |
| Acquisitions (net) | $70,000 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | -$18.2M | -$39.9M | $1.4M | -$14.3M | -$10.9M |
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 11:40pm (8h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue | $0 |
$1.2M $1.2M – $1.2M
|
$11.6M $11.6M – $11.6M
|
$29.4M $29.4M – $29.4M
|
| EBITDA | $0 |
$-700,000 $-700,000 – $-700,000
|
-$7.0M -$7.0M – -$7.0M
|
-$17.7M -$17.7M – -$17.7M
|
| Net Income |
-$23.9M -$34.2M – -$13.6M
|
-$25.7M -$49.8M – -$1.6M
|
-$21.2M -$21.2M – -$21.2M
|
-$15.2M -$15.2M – -$15.2M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 26, 2026 11:40pm (8h ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | +81.8% | -49.9% | -66.0% | -100.0% |
| Gross Profit Growth | +60.0% | -57.7% | -56.5% | -101.5% |
| Operating Income Growth | +1.7% | -38.8% | +54.1% | +52.0% |
| Net Income Growth | +3.4% | -38.7% | +40.2% | +74.3% |
| EBITDA Growth | +3.5% | -40.4% | +46.8% | +71.1% |
Insider Trading (Recent)
All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-09 | Shiff Susan Ph.D. | A-Award | 6,000.00 | $2.78 | $16,680 |
| 2026-06-09 | Smith Cynthia | A-Award | 6,000.00 | $2.78 | $16,680 |
| 2026-06-09 | Shah Sujal | A-Award | 6,000.00 | $2.78 | $16,680 |
| 2026-06-09 | HALL WALLACE L JR | A-Award | 6,000.00 | $2.78 | $16,680 |
| 2026-06-09 | WYZGA MICHAEL S | A-Award | 6,000.00 | $2.78 | $16,680 |
| 2026-01-29 | O'Brien Stephen Paul | A-Award | 15,000.00 | $3.90 | $58,500 |
| 2026-01-29 | Conn Avi Daniel | A-Award | 45,000.00 | $3.90 | $175,500 |
| 2026-01-29 | Kauh John Saewook M.D. | A-Award | 45,000.00 | $3.90 | $175,500 |
| 2026-01-29 | Alibhai Imran Nizamudin | A-Award | 115,000.00 | $3.90 | $448,500 |
| 2025-12-16 | O'Brien Stephen Paul | A-Award | 4,000.00 | $4.20 | $16,800 |
| 2025-12-16 | Kauh John Saewook M.D. | A-Award | 17,500.00 | $4.20 | $73,500 |
| 2025-12-16 | Conn Avi Daniel | A-Award | 17,500.00 | $4.20 | $73,500 |
| 2025-12-16 | Alibhai Imran Nizamudin | A-Award | 47,500.00 | $4.20 | $199,500 |
| 2025-07-07 | Tweardy Samuel David | J-Other | 315,658.00 | $0.00 | $0 |
| 2025-04-15 | HALL WALLACE L JR | A-Award | 202,044.00 | $0.00 | $0 |
| 2025-04-15 | HALL WALLACE L JR | A-Award | 44,712.00 | $0.00 | $0 |
| 2025-04-15 | Wirk Shaheen | A-Award | 263,164.00 | $0.00 | $0 |
| 2025-04-15 | Wirk Shaheen | A-Award | 176,030.00 | $0.00 | $0 |
| 2025-04-15 | Tweardy Samuel David | 0.00 | $0.00 | $0 | |
| 2025-04-17 | Larson Jeffrey Leroy | A-Award | 10,820.00 | $17.04 | $184,373 |
Narrative Economics
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