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X4 Pharmaceuticals, Inc.

XFOR NASDAQ Categories PDF
Healthcare · Biotechnology
Boston, MA 02134, United States IPO 2017 x4pharma.com Updated Jul 11, 2:02pm
Price
$4.41
Market Cap
$415.9M
Employees
45
Beta
0.35
Avg Volume
599,275
CEO
Adam R. Craig

X4 Pharmaceuticals, Inc. is a biopharmaceutical firm committed to the discovery, development, and commercialization of innovative therapies for uncommon immune system disorders. Its primary drug candidate, XOLREMDI (also known as mavorixafor), is an orally administered, small-molecule antagonist specifically designed to target the chemokine receptor CXCR4. This compound is currently undergoing Phase 3 clinical trials for the management of WHIM syndrome, a rare immunodeficiency characterized by symptoms such as warts, hypogammaglobulinemia, recurrent infections, and myelokathexis. To broaden its global presence, the company has entered into several licensing agreements: A partnership with Abbisko Therapeutics Co Ltd. grants rights for the manufacturing and distribution of XOLREMDI in mainland China, Taiwan, Hong Kong, and Macau. Another agreement with Norgine covers the development, production, and commercialization of mavorixafor across Europe, Australia, and New Zealand. Furthermore, X4 Pharmaceuticals holds a comprehensive agreement with Genzyme Corporation concerning the CXCR4 receptor, allowing for the development and commercialization of licensed compounds for all medical applications, including therapeutic, preventive, and diagnostic uses. The company maintains its corporate headquarters in Boston, Massachusetts.

Runs with full report
Price Overview
Last updated: Jul 11, 2026 4:37pm (just now)
Current data · timestamped when a report runs
$4.41
Change · Jul 11
+0.45 (+11.36%)
Day Range
$3.93 – $4.44
52-Week Range
$1.35 – $4.83
50-Day MA
$4.07
200-Day MA
$3.82
Volume
912,735.00
Analyst Price Targets
Low $11.00
Consensus $11.67
High $12.00
(10 analysts)
Share Structure
Outstanding 94,319,696.00
Float 57,527,469.00
Free Float 61.0%
Normal free float — 61.0% of shares trade freely, ~39% held by insiders/institutions
Healthy float typical of established companies. Good liquidity for entering and exiting positions without major price impact.
Price History (1 Year)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jul 11, 2026 2:02pm (2h ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-2.36
Stock Price: $4.41
EPS (Diluted): -1.87
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
0.91
Stock Price: $4.41
Total Equity: $186.29M
Shares: 42,292,818
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-3.07
Market Cap: $415.95M
Total Debt: $76.29M
Cash: $217.05M
EBITDA: -$69.01M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$29.4M
Market Cap: $415.95M
Total Debt: $76.29M
Cash: $217.05M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
4.82
Stock Price: $4.41
Revenue: $35.11M
Shares: 42,292,818
EV/Sales (Total value vs revenue — works when P/E can't)
API
0.84
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
82.2%
Gross Profit: $28.86M
Revenue: $35.11M
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
-247.4%
Operating Income: -$86.88M
Revenue: $35.11M
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
-225.6%
Net Income: -$79.20M
Revenue: $35.11M
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-94.9%
Net Income: -$79.20M
Total Equity: $186.29M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-39.5%
Operating Income: -$86.88M
Tax Rate: -0.1%
Equity: $186.29M
Total Debt: $76.29M
Cash: $217.05M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
10.16
Current Assets: $261.58M
Current Liabilities: $25.76M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.41
Short-Term Debt: $0.00
Long-Term Debt: $76.29M
Total Debt: $76.29M
Total Equity: $186.29M
Rev/Share (Top-line per share)
CALC
Revenue / Shares Outstanding
$0.83
Revenue: $35.11M
Shares: 42,292,818
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$4.40
Total Equity: $186.29M
Shares: 42,292,818
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-2.10
Operating CF: -$85.62M
CapEx: -$3.00M
Shares: 42,292,818
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $4.41
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$79.20M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares XFOR against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Metric 2021 2022 2023 2024 2025
Revenue $0 $0 $0 $2.6M $35.1M
Cost of Revenue $1.9M $0 $0 $797,000 $6.3M
Gross Profit -$1.9M $0 $0 $1.8M $28.9M
Operating Expenses $73.5M $87.6M $107.5M $38.2M $115.7M
Operating Income -$75.3M -$87.6M -$107.5M -$36.4M -$86.9M
Net Income -$88.7M -$93.9M -$101.2M -$37.5M -$79.2M
EBITDA -$83.1M -$89.3M -$94.9M -$27.6M -$69.0M
EPS $-119.58 $-45.60 $-17.07 $-5.59 $-1.87
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $81.8M $121.7M $99.2M $55.7M $217.0M
Total Current Assets $87.9M $128.7M $122.1M $112.2M $261.6M
Total Assets $117.2M $155.6M $147.3M $146.4M $290.5M
Current Liabilities $14.0M $22.3M $22.9M $32.9M $25.8M
Long-Term Debt $33.1M $32.3M $54.6M $75.4M $76.3M
Total Liabilities $52.8M $81.5M $96.2M $124.3M $104.2M
Total Equity $64.4M $74.1M $51.1M $22.1M $186.3M
Retained Earnings -$282.9M -$376.7M -$477.9M -$515.4M -$594.6M
Cash Flow (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$70.9M -$77.1M -$96.5M -$130.9M -$85.6M
Capital Expenditure $-615,000 $-103,000 $-60,000 -$7.3M -$3.0M
Free Cash Flow -$71.5M -$77.2M -$96.6M -$138.2M -$88.6M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks -$2.0M $0 $0 $0 $0
Net Change in Cash $2.8M $39.9M -$22.8M -$43.8M $161.4M
Analyst Estimates (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Metric 2027 2028 2029 2030
Revenue $9.6M
$7.5M – $11.6M
$100.6M
$100.6M – $100.6M
$308.5M
$235.0M – $359.3M
$629.4M
$479.4M – $733.0M
EBITDA $1.9M
$1.5M – $2.3M
$20.1M
$20.1M – $20.1M
$61.7M
$47.0M – $71.9M
$125.9M
$95.9M – $146.6M
Net Income -$33.7M
-$42.7M – -$24.7M
-$25.9M
-$40.5M – -$11.3M
$5.4M
$3.7M – $6.5M
$58.8M
$40.6M – $71.4M
EPS
Growth Trends (YoY %)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Metric 2022 2023 2024 2025
Revenue Growth +1,273.2%
Gross Profit Growth +100.0% +1,539.5%
Operating Income Growth -16.2% -22.8% +66.1% -138.7%
Net Income Growth -5.8% -7.8% +63.0% -111.5%
EBITDA Growth -7.4% -6.2% +70.9% -150.2%
Insider Trading (Recent)
Last updated: Jul 11, 2026 2:02pm (2h ago)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-06-30 KIRSKE DAVID S-Sale 8,543.00 $4.26 $36,428
2026-07-01 Gold Kelly A-Award 110,000.00 $4.09 $449,350
2026-07-01 Gold Kelly 0.00 $0.00 $0
2026-05-12 KIRSKE DAVID S-Sale 16,961.00 $4.29 $72,820
2026-01-01 Bridger Gary A-Award 110,000.00 $4.00 $440,000
2026-01-01 de Craecker Francoise A-Award 110,000.00 $4.00 $440,000
2026-01-01 WYZGA MICHAEL S A-Award 110,000.00 $4.00 $440,000
2026-01-01 Stewart Murray A-Award 110,000.00 $4.00 $440,000
2025-10-29 Craig Adam R A-Award 2,329,154.00 $1.42 $3.3M
2025-10-29 Volpone John A-Award 2,329,154.00 $1.42 $3.3M
2025-10-29 KIRSKE DAVID A-Award 1,552,769.00 $1.42 $2.2M
2025-10-23 Craig Adam R P-Purchase 86,206.00 $2.90 $249,997
2025-08-12 Volpone John A-Award 1,609,873.00 $1.42 $2.3M
2025-08-14 Volpone John A-Award 529,201.00 $3.14 $1.7M
2025-08-14 Volpone John A-Award 289,881.00 $0.00 $0
2025-08-12 Craig Adam R 0.00 $0.00 $0
2025-08-12 KIRSKE DAVID 0.00 $0.00 $0
2025-08-12 Craig Adam R A-Award 1,609,873.00 $1.42 $2.3M
2025-08-14 Craig Adam R A-Award 529,201.00 $3.14 $1.7M
2025-08-14 Craig Adam R A-Award 289,881.00 $0.00 $0
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for XFOR — it's generated by the pipeline (market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.406 · 9aebe10a · 2026-07-11 16:07:30