X4 Pharmaceuticals, Inc. is a biopharmaceutical firm committed to the discovery, development, and commercialization of innovative therapies for uncommon immune system disorders. Its primary drug candidate, XOLREMDI (also known as mavorixafor), is an orally administered, small-molecule antagonist specifically designed to target the chemokine receptor CXCR4. This compound is currently undergoing Phase 3 clinical trials for the management of WHIM syndrome, a rare immunodeficiency characterized by symptoms such as warts, hypogammaglobulinemia, recurrent infections, and myelokathexis. To broaden its global presence, the company has entered into several licensing agreements: A partnership with Abbisko Therapeutics Co Ltd. grants rights for the manufacturing and distribution of XOLREMDI in mainland China, Taiwan, Hong Kong, and Macau. Another agreement with Norgine covers the development, production, and commercialization of mavorixafor across Europe, Australia, and New Zealand. Furthermore, X4 Pharmaceuticals holds a comprehensive agreement with Genzyme Corporation concerning the CXCR4 receptor, allowing for the development and commercialization of licensed compounds for all medical applications, including therapeutic, preventive, and diagnostic uses. The company maintains its corporate headquarters in Boston, Massachusetts.
Price Overview
Last updated: Jul 11, 2026 4:37pm (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -1.87
Total Equity: $186.29M
Shares: 42,292,818
Total Debt: $76.29M
Cash: $217.05M
EBITDA: -$69.01M
Total Debt: $76.29M
Cash: $217.05M
Revenue: $35.11M
Shares: 42,292,818
Revenue: $35.11M
Revenue: $35.11M
Revenue: $35.11M
Total Equity: $186.29M
Tax Rate: -0.1%
Equity: $186.29M
Total Debt: $76.29M
Cash: $217.05M
Current Liabilities: $25.76M
Long-Term Debt: $76.29M
Total Debt: $76.29M
Total Equity: $186.29M
Shares: 42,292,818
Shares: 42,292,818
CapEx: -$3.00M
Shares: 42,292,818
Stock Price: $4.41
Net Income: -$79.20M
Industry Benchmarks
Deep Analysis
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Income Statement (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $2.6M | $35.1M |
| Cost of Revenue | $1.9M | $0 | $0 | $797,000 | $6.3M |
| Gross Profit | -$1.9M | $0 | $0 | $1.8M | $28.9M |
| Operating Expenses | $73.5M | $87.6M | $107.5M | $38.2M | $115.7M |
| Operating Income | -$75.3M | -$87.6M | -$107.5M | -$36.4M | -$86.9M |
| Net Income | -$88.7M | -$93.9M | -$101.2M | -$37.5M | -$79.2M |
| EBITDA | -$83.1M | -$89.3M | -$94.9M | -$27.6M | -$69.0M |
| EPS | $-119.58 | $-45.60 | $-17.07 | $-5.59 | $-1.87 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $81.8M | $121.7M | $99.2M | $55.7M | $217.0M |
| Total Current Assets | $87.9M | $128.7M | $122.1M | $112.2M | $261.6M |
| Total Assets | $117.2M | $155.6M | $147.3M | $146.4M | $290.5M |
| Current Liabilities | $14.0M | $22.3M | $22.9M | $32.9M | $25.8M |
| Long-Term Debt | $33.1M | $32.3M | $54.6M | $75.4M | $76.3M |
| Total Liabilities | $52.8M | $81.5M | $96.2M | $124.3M | $104.2M |
| Total Equity | $64.4M | $74.1M | $51.1M | $22.1M | $186.3M |
| Retained Earnings | -$282.9M | -$376.7M | -$477.9M | -$515.4M | -$594.6M |
Cash Flow (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$70.9M | -$77.1M | -$96.5M | -$130.9M | -$85.6M |
| Capital Expenditure | $-615,000 | $-103,000 | $-60,000 | -$7.3M | -$3.0M |
| Free Cash Flow | -$71.5M | -$77.2M | -$96.6M | -$138.2M | -$88.6M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | -$2.0M | $0 | $0 | $0 | $0 |
| Net Change in Cash | $2.8M | $39.9M | -$22.8M | -$43.8M | $161.4M |
Analyst Estimates (Annual)
Last updated: Jul 11, 2026 2:02pm (2h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$9.6M $7.5M – $11.6M
|
$100.6M $100.6M – $100.6M
|
$308.5M $235.0M – $359.3M
|
$629.4M $479.4M – $733.0M
|
| EBITDA |
$1.9M $1.5M – $2.3M
|
$20.1M $20.1M – $20.1M
|
$61.7M $47.0M – $71.9M
|
$125.9M $95.9M – $146.6M
|
| Net Income |
-$33.7M -$42.7M – -$24.7M
|
-$25.9M -$40.5M – -$11.3M
|
$5.4M $3.7M – $6.5M
|
$58.8M $40.6M – $71.4M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jul 11, 2026 2:02pm (2h ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | — | — | +1,273.2% |
| Gross Profit Growth | +100.0% | — | — | +1,539.5% |
| Operating Income Growth | -16.2% | -22.8% | +66.1% | -138.7% |
| Net Income Growth | -5.8% | -7.8% | +63.0% | -111.5% |
| EBITDA Growth | -7.4% | -6.2% | +70.9% | -150.2% |
Insider Trading (Recent)
Last updated: Jul 11, 2026 2:02pm (2h ago)All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-30 | KIRSKE DAVID | S-Sale | 8,543.00 | $4.26 | $36,428 |
| 2026-07-01 | Gold Kelly | A-Award | 110,000.00 | $4.09 | $449,350 |
| 2026-07-01 | Gold Kelly | 0.00 | $0.00 | $0 | |
| 2026-05-12 | KIRSKE DAVID | S-Sale | 16,961.00 | $4.29 | $72,820 |
| 2026-01-01 | Bridger Gary | A-Award | 110,000.00 | $4.00 | $440,000 |
| 2026-01-01 | de Craecker Francoise | A-Award | 110,000.00 | $4.00 | $440,000 |
| 2026-01-01 | WYZGA MICHAEL S | A-Award | 110,000.00 | $4.00 | $440,000 |
| 2026-01-01 | Stewart Murray | A-Award | 110,000.00 | $4.00 | $440,000 |
| 2025-10-29 | Craig Adam R | A-Award | 2,329,154.00 | $1.42 | $3.3M |
| 2025-10-29 | Volpone John | A-Award | 2,329,154.00 | $1.42 | $3.3M |
| 2025-10-29 | KIRSKE DAVID | A-Award | 1,552,769.00 | $1.42 | $2.2M |
| 2025-10-23 | Craig Adam R | P-Purchase | 86,206.00 | $2.90 | $249,997 |
| 2025-08-12 | Volpone John | A-Award | 1,609,873.00 | $1.42 | $2.3M |
| 2025-08-14 | Volpone John | A-Award | 529,201.00 | $3.14 | $1.7M |
| 2025-08-14 | Volpone John | A-Award | 289,881.00 | $0.00 | $0 |
| 2025-08-12 | Craig Adam R | 0.00 | $0.00 | $0 | |
| 2025-08-12 | KIRSKE DAVID | 0.00 | $0.00 | $0 | |
| 2025-08-12 | Craig Adam R | A-Award | 1,609,873.00 | $1.42 | $2.3M |
| 2025-08-14 | Craig Adam R | A-Award | 529,201.00 | $3.14 | $1.7M |
| 2025-08-14 | Craig Adam R | A-Award | 289,881.00 | $0.00 | $0 |
Narrative Economics
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