Healthcare · Biotechnology
Price
$18.03
Market Cap
$203.6M
Employees
23
Beta
0.82
Avg Volume
1,754,858
CEO
Garry A. Neil
Business Description
Avalo Therapeutics, Inc. is a precision medicine company in the clinical development phase, dedicated to identifying, advancing, and marketing specialized treatments for patients experiencing critical unmet medical needs across the fields of immunology, immuno-oncology, and rare genetic disorders. Among its key pipeline assets is AVTX-002, a fully human monoclonal antibody designed to inhibit LIGHT. This drug is currently undergoing Phase II clinical trials for non-eosinophilic asthma and inflammatory bowel diseases, specifically moderate to severe Crohn's disease and ulcerative colitis. Furthermore, AVTX-002 is also being investigated in Phase III for its potential to treat acute respiratory distress syndrome caused by COVID-19. The company is also advancing AVTX-007, a fully human monoclonal antibody targeting IL-18, which is progressing through Phase I clinical studies for Still's disease, encompassing both adult-onset Still's disease and systemic juvenile idiopathic arthritis. Avalo's late-stage pipeline includes two products addressing rare genetic conditions, both in Phase III clinical trials: AVTX-801, a D-galactose substrate replacement therapy for phosphoglucomutase 1 deficiency (PGM1), also known as PGM1-CDG; and AVTX-803, an L-fucose substrate replacement therapy intended for LADII, medically referred to as SLC35C1-CDG. Established in 2011, the corporation initially operated as Cerecor Inc. before rebranding as Avalo Therapeutics, Inc. in August 2021. Its main operations are situated in Rockville, Maryland.
Business History
Price Overview
Last updated: Jun 27, 2026 9:04am (just now)$18.20
+0.20 (+1.11%)
Day Range
$17.65 – $18.46
52-Week Range
$4.61 – $24.27
50-Day MA
$15.86
200-Day MA
$15.73
Volume
8,576,580.00
Analyst Price Targets
Low
$34.00
Consensus
$47.14
High
$60.00
(11 analysts)
Share Structure
Outstanding
11,294,117.00
Float
10,838,129.00
Free Float
96.0%
High free float
— 96.0% of shares trade freely, ~4% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Price History (1 Year)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
API Direct from provider
CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALCStock Price / EPS (Diluted)
-3.09
Stock Price: $18.03
EPS (Diluted): -5.84
EPS (Diluted): -5.84
P/B Ratio (Price vs net asset value)
APIStock Price / Book Value Per Share
2.93
Stock Price: $18.03
Total Equity: $83.05M
Shares: 13,404,830
Total Equity: $83.05M
Shares: 13,404,830
EV/EBITDA (Total value vs operating profit)
APIEnterprise Value / EBITDA
-2.17
Market Cap: $203.59M
Total Debt: $2.00M
Cash: $15.86M
EBITDA: -$77.75M
Total Debt: $2.00M
Cash: $15.86M
EBITDA: -$77.75M
Enterprise Value (Takeover price (cap + debt - cash))
APIMarket Cap + Total Debt - Cash
$230.0M
Market Cap: $203.59M
Total Debt: $2.00M
Cash: $15.86M
Total Debt: $2.00M
Cash: $15.86M
P/S Ratio (Price per dollar of revenue)
APIStock Price / Revenue Per Share
4,125.96
Stock Price: $18.03
Revenue: $59,000
Shares: 13,404,830
Revenue: $59,000
Shares: 13,404,830
EV/Sales (Total value vs revenue — works when P/E can't)
API3,898.32
Gross Margin (Revenue left after direct costs)
APIGross Profit / Revenue
100.0%
Gross Profit: $59,000
Revenue: $59,000
Revenue: $59,000
Operating Margin (Revenue left after all operations)
APIOperating Income / Revenue
-123,601.7%
Operating Income: -$72.93M
Revenue: $59,000
Revenue: $59,000
Net Margin (Revenue left as actual profit)
APINet Income / Revenue
-132,642.4%
Net Income: -$78.26M
Revenue: $59,000
Revenue: $59,000
ROE (Profit from shareholder equity)
APINet Income / Total Equity
-97.5%
Net Income: -$78.26M
Total Equity: $83.05M
Total Equity: $83.05M
ROIC (Profit from all invested capital)
APINOPAT / Invested Capital
-89.3%
Operating Income: -$72.93M
Tax Rate: -0.2%
Equity: $83.05M
Total Debt: $2.00M
Cash: $15.86M
Tax Rate: -0.2%
Equity: $83.05M
Total Debt: $2.00M
Cash: $15.86M
Current Ratio (Can it pay short-term bills)
APICurrent Assets / Current Liabilities
8.14
Current Assets: $105.29M
Current Liabilities: $12.94M
Current Liabilities: $12.94M
Debt/Equity (Leverage — debt vs equity)
CALCTotal Debt / Total Equity
0.02
Short-Term Debt: $0.00
Long-Term Debt: $2.00M
Total Debt: $2.00M
Total Equity: $83.05M
Long-Term Debt: $2.00M
Total Debt: $2.00M
Total Equity: $83.05M
Rev/Share (Top-line per share)
CALCRevenue / Shares Outstanding
$0.00
Revenue: $59,000
Shares: 13,404,830
Shares: 13,404,830
Book Value/Share (Net assets per share)
CALC(Total Assets - Total Liabilities) / Shares
$6.20
Total Equity: $83.05M
Shares: 13,404,830
Shares: 13,404,830
FCF/Share (Real cash generated per share)
CALC(Operating Cash Flow + CapEx) / Shares
$-3.84
Operating CF: -$51.46M
CapEx: $0.00
Shares: 13,404,830
CapEx: $0.00
Shares: 13,404,830
Div Yield (Annual income from holding)
APILast Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $18.03
Stock Price: $18.03
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
—
Dividends Paid: N/A
Net Income: -$78.26M
Net Income: -$78.26M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares AVTX against LLM-researched typical ranges for its
industry. One research call per industry, cached indefinitely — every stock in the same industry
reuses the same baseline.
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
0
Company Classification
— What type of company is this?
1
Industry Landscape
— Where is the industry headed?
2
Company Momentum
— Where is this company trending?
3
Forward Projection
— 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a
DCF Valuation
— Present value of future cash flows
4b
Earnings Power Value
— Floor value — worth with zero growth
4c
Anchored PE
— Industry PE adjusted for growth differential
4d
Reverse DCF
— What growth is the market pricing in?
4e
Revenue-Based DCF
— For growth/narrative companies (skip if mature earner)
4f
Anchored P/S
— Price-to-Sales peer comparison (skip if mature earner)
4g
Scenario Analysis
— Bull / Base / Bear (skip if mature earner)
4h
Dividend Discount Model
— For dividend/income stocks only
4i
Book Value Analysis
— For deep value / turnaround stocks only
4j
Insider Activity
— Are insiders buying or selling?
4f
Cash Flow Quality
— How trustworthy is the FCF?
4g
Debt Maturity Risk
— Can it handle its debt?
4h
Macro Environment
— Rates, market valuation, volatility
4i
Sector Intelligence
— How does this company compare within its sector?
4j
Revenue Confidence
— How reliable is the growth projection?
4k
Sensitivity Analysis
— How fragile is the fair value estimate?
4l
Sector Demand Cycle
— Is the sector in a boom, steady state, or contraction?
5
AI Investigation
— Adaptive research engine (Claude)
5b
Thesis Evaluation
— What does the market believe? (narrative/platform stocks only)
6
Valuation Synthesis
— Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 23, 2026 6:20pm (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $5.4M | $18.1M | $1.9M | $441,000 | $59,000 |
| Cost of Revenue | $1.5M | $3.4M | $1.3M | $-366,000 | $0 |
| Gross Profit | $3.9M | $14.6M | $640,000 | $807,000 | $59,000 |
| Operating Expenses | $86.0M | $52.1M | $28.0M | $69.3M | $73.0M |
| Operating Income | -$82.1M | -$37.4M | -$27.4M | -$68.5M | -$72.9M |
| Net Income | -$84.4M | -$41.7M | -$31.5M | -$35.1M | -$78.3M |
| EBITDA | -$80.5M | -$37.3M | -$23.3M | -$34.8M | -$77.8M |
| EPS | $-2,330.66 | $-1,062.65 | $-113.58 | $-4.32 | $-5.84 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 23, 2026 6:20pm (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $54.6M | $13.2M | $7.4M | $134.5M | $15.9M |
| Total Current Assets | $61.8M | $16.4M | $8.4M | $138.9M | $105.3M |
| Total Assets | $80.2M | $33.4M | $21.0M | $150.7M | $116.5M |
| Current Liabilities | $19.9M | $22.1M | $4.6M | $7.0M | $12.9M |
| Long-Term Debt | $32.8M | $13.5M | $0 | $0 | $2.0M |
| Total Liabilities | $57.1M | $44.3M | $13.7M | $17.7M | $33.4M |
| Total Equity | $23.1M | -$10.9M | $7.3M | $133.0M | $83.0M |
| Retained Earnings | -$262.2M | -$303.8M | -$335.1M | -$370.3M | -$448.5M |
Cash Flow (Annual)
Last updated: Jun 23, 2026 6:20pm (3d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$70.9M | -$26.8M | -$30.7M | -$49.1M | -$51.5M |
| Capital Expenditure | $-113,000 | $-95,000 | $-158,000 | $0 | $0 |
| Free Cash Flow | -$71.0M | -$26.8M | -$30.8M | -$49.1M | -$51.5M |
| Acquisitions (net) | $0 | $0 | $0 | $356,000 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $35.8M | -$41.4M | -$5.8M | $127.1M | -$118.6M |
Analyst Estimates (Annual)
Last updated: Jun 27, 2026 9:04am (just now)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$1.0M $1.0M – $1.0M
|
$13,884 $13,884 – $13,884
|
$11.1M $11.1M – $11.1M
|
$106.5M $106.5M – $106.5M
|
| EBITDA |
-$1.0M -$1.0M – -$1.0M
|
$-13,884 $-13,884 – $-13,884
|
-$11.1M -$11.1M – -$11.1M
|
-$106.5M -$106.5M – -$106.5M
|
| Net Income |
-$48.1M -$72.7M – -$23.6M
|
-$40.3M -$56.4M – -$24.2M
|
-$32.6M -$32.6M – -$32.6M
|
-$17.5M -$17.5M – -$17.5M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 23, 2026 6:20pm (3d ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | +234.4% | -89.3% | -77.1% | -86.6% |
| Gross Profit Growth | +274.1% | -95.6% | +26.1% | -92.7% |
| Operating Income Growth | +54.4% | +26.9% | -150.5% | -6.4% |
| Net Income Growth | +50.6% | +24.3% | -11.4% | -122.8% |
| EBITDA Growth | +53.7% | +37.6% | -49.6% | -123.1% |
Insider Trading (Recent)
Type codes
PPurchase
SSale
AAward / grant
MOption exercise
FIn-kind (tax)
CConversion
GGift
DReturn to issuer
All SEC Form 4 codes
Open market
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
Compensation (Rule 16b-3)
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
Other exempt
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
Other
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-23 | Doyle Mittie | M-Exempt | 1,450.00 | $8.04 | $11,658 |
| 2026-06-23 | Doyle Mittie | M-Exempt | 1,450.00 | $8.04 | $11,658 |
| 2026-06-23 | Doyle Mittie | S-Sale | 1,450.00 | $18.00 | $26,100 |
| 2026-06-23 | Philip Ron M | A-Award | 40,200.00 | $17.83 | $716,766 |
| 2026-06-23 | Philip Ron M | 0.00 | $0.00 | $0 | |
| 2026-06-10 | Riley Jennifer | F-InKind | 588.00 | $13.10 | $7,703 |
| 2026-06-10 | VARKI PAUL | F-InKind | 1,081.00 | $13.10 | $14,161 |
| 2026-06-10 | Sullivan Christopher Ryan | F-InKind | 138.00 | $13.10 | $1,808 |
| 2026-06-10 | Doyle Mittie | F-InKind | 1,084.00 | $13.10 | $14,200 |
| 2026-06-02 | Lind Kevin Robert | A-Award | 20,100.00 | $13.96 | $280,596 |
| 2026-06-02 | Truex Samantha | A-Award | 20,100.00 | $13.96 | $280,596 |
| 2026-06-02 | KAPLAN GILLA | A-Award | 20,100.00 | $13.96 | $280,596 |
| 2026-06-02 | KANTOFF AARON | A-Award | 20,100.00 | $13.96 | $280,596 |
| 2026-06-02 | Heffernan Michael Thomas | A-Award | 29,500.00 | $13.96 | $411,820 |
| 2026-06-02 | Jain Rita | A-Award | 20,100.00 | $13.96 | $280,596 |
| 2026-05-28 | Doyle Mittie | M-Exempt | 679.00 | $8.04 | $5,459 |
| 2026-05-28 | Doyle Mittie | M-Exempt | 679.00 | $8.04 | $5,459 |
| 2026-05-28 | Doyle Mittie | S-Sale | 679.00 | $16.00 | $10,864 |
| 2026-05-21 | Riley Jennifer | A-Award | 34,200.00 | $0.00 | $0 |
| 2026-05-21 | Sullivan Christopher Ryan | A-Award | 39,900.00 | $0.00 | $0 |
Narrative Economics
The story the market is telling about this stock — the intangible X-factor
(founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond
what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for AVTX — it's generated by the pipeline (
market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30