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Summit Therapeutics Inc.

SMMT NASDAQ Categories PDF
Healthcare · Biotechnology
Cambridge, MA 02142, United States IPO 2015 summittxinc.com Updated Jun 27, 12:53am
Price
$14.01
Market Cap
$10.9B
Employees
159
Beta
-1.31
Avg Volume
5,157,431
CEO
Robert W. Duggan
Business Description

Summit Therapeutics Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing therapeutic solutions, primarily targeting infectious diseases across the United States and Latin America. The company's clinical development pipeline is heavily concentrated on therapies for Clostridioides difficile infection (CDI). Its flagship product candidate, ridinilazole, is an orally administered small molecule antibiotic currently advancing through Phase III clinical trials as a treatment for CDI. Beyond its lead asset, Summit Therapeutics is also progressing SMT-738, designed to combat multidrug-resistant infections, notably carbapenem-resistant Enterobacteriaceae (CRE). Additionally, its DDS-04 series represents a potential therapeutic avenue for various infections caused by the Enterobacteriaceae family of bacteria. Established in 2003, the company maintains its headquarters in Cambridge, Massachusetts.

Business History
Price Overview
Last updated: Jun 27, 2026 9:05am (just now)
$14.01
-0.17 (-1.20%)
Day Range
$13.88 – $14.25
52-Week Range
$12.55 – $30.98
50-Day MA
$17.49
200-Day MA
$17.76
Volume
3,919,920.00
Analyst Price Targets
Low $16.00
Consensus $19.50
High $23.00
(20 analysts)
Share Structure
Outstanding 776,162,645.00
Float 107,365,076.00
Free Float 13.8%
Very low free float — 13.8% of shares trade freely, ~86.2% held by insiders/institutions
Thinly traded — expect wider bid-ask spreads and sharp price swings on modest volume. Institutional investors may avoid due to liquidity constraints.
Price History (1 Year)
Last updated: Jun 27, 2026 12:53am (8h ago)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jun 20, 2026 10:04am (6d ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-9.73
Stock Price: $14.01
EPS (Diluted): -1.44
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
26.74
Stock Price: $14.01
Total Equity: $488.98M
Shares: 747,700,000
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-10.25
Market Cap: $10.87B
Total Debt: $0.00
Cash: $167.18M
EBITDA: -$1.08B
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$12.9B
Market Cap: $10.87B
Total Debt: $0.00
Cash: $167.18M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
0.00
Stock Price: $14.01
Revenue: $0.00
Shares: 747,700,000
EV/Sales (Total value vs revenue — works when P/E can't)
API
0.00
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
0.0%
Gross Profit: $0.00
Revenue: $0.00
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
0.0%
Operating Income: -$1.09B
Revenue: $0.00
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
0.0%
Net Income: -$1.08B
Revenue: $0.00
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-340.6%
Net Income: -$1.08B
Total Equity: $488.98M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-248.1%
Operating Income: -$1.09B
Tax Rate: 0.0%
Equity: $488.98M
Total Debt: $0.00
Cash: $167.18M
Zero debt — invested capital = equity minus cash (very efficient)
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
9.87
Current Assets: $534.58M
Current Liabilities: $54.17M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
0.00
Short-Term Debt: $0.00
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: $488.98M
Zero debt — this company carries no debt obligations. Strongest possible score.
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
Revenue: $0.00
Shares: 747,700,000
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$0.65
Total Equity: $488.98M
Shares: 747,700,000
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-0.32
Operating CF: -$239.67M
CapEx: -$487,599
Shares: 747,700,000
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $14.01
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$1.08B
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares SMMT against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 20, 2026 10:04am (6d ago)
Metric 2021 2022 2023 2024 2025
Revenue $1.3M $583,190 $0 $0 $0
Cost of Revenue $0 $0 $0 $0 $0
Gross Profit $1.3M $583,190 $0 $0 $0
Operating Expenses $65.1M $60.2M $478.2M $180.5M $1.1B
Operating Income -$63.7M -$59.6M -$478.2M -$180.5M -$1.1B
Net Income -$65.5M -$65.2M -$482.4M -$176.8M -$1.1B
EBITDA -$64.3M -$51.6M -$69.5M -$168.5M -$1.1B
EPS $-0.71 $-0.34 $-0.78 $-0.25 $-1.44
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jun 20, 2026 10:04am (6d ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $53.2M $284.2M $56.5M $83.8M $167.2M
Total Current Assets $72.1M $535.3M $150.1M $338.6M $534.6M
Total Assets $84.0M $541.4M $160.6M $348.1M $557.5M
Current Liabilities $19.0M $31.6M $16.1M $33.3M $54.2M
Long-Term Debt $0 $403.1M $79.1M $0 $0
Total Liabilities $22.3M $438.2M $99.1M $37.4M $68.5M
Total Equity $61.7M $103.2M $61.5M $310.6M $489.0M
Retained Earnings -$222.0M -$308.4M -$786.0M -$970.6M -$1.7B
Cash Flow (Annual)
Last updated: Jun 20, 2026 10:04am (6d ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$53.8M -$33.9M -$60.7M -$113.6M -$239.7M
Capital Expenditure $-226,830 $-508,681 $-101,293 $-111,073 $-487,599
Free Cash Flow -$54.0M -$34.4M -$60.8M -$113.7M -$240.2M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $4.0M $470.2M -$456.8M $27.0M $89.4M
Analyst Estimates (Annual)
Last updated: Jun 27, 2026 12:53am (8h ago)
Metric 2027 2028 2029 2030
Revenue $76.1M
$64.0M – $88.3M
$731.7M
$600.5M – $863.0M
$2.0B
$1.6B – $2.3B
$3.9B
$3.2B – $4.6B
EBITDA $15.2M
$12.8M – $17.7M
$146.3M
$120.1M – $172.6M
$395.7M
$324.7M – $466.7M
$785.1M
$644.3M – $925.9M
Net Income -$898.7M
-$996.5M – -$738.9M
-$438.3M
-$742.1M – $207.1M
$243.3M
$186.5M – $300.0M
$1.3B
$984.1M – $1.6B
EPS
Growth Trends (YoY %)
Last updated: Jun 20, 2026 10:04am (6d ago)
Metric 2022 2023 2024 2025
Revenue Growth -56.4% -100.0%
Gross Profit Growth -56.4% -100.0%
Operating Income Growth +6.4% -701.9% +62.3% -506.3%
Net Income Growth +0.5% -640.2% +63.4% -510.7%
EBITDA Growth +19.8% -34.6% -142.6% -540.8%
Insider Trading (Recent)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-06-12 Zanganeh Mahkam P-Purchase 3,810,000.00 $13.12 $50.0M
2026-06-12 DUGGAN ROBERT W P-Purchase 3,810,000.00 $13.12 $50.0M
2026-06-04 DUGGAN ROBERT W P-Purchase 100,000.00 $14.60 $1.5M
2026-06-04 Zanganeh Mahkam P-Purchase 100,000.00 $14.60 $1.5M
2026-06-04 Soni Manmeet Singh P-Purchase 25,000.00 $14.43 $360,750
2026-06-04 Soni Manmeet Singh P-Purchase 25,000.00 $14.46 $361,500
2026-01-08 Anand Bhaskar A-Award 30,000.00 $18.83 $564,900
2026-01-02 Zanganeh Mahkam A-Award 11,232.00 $17.52 $196,785
2026-01-02 DUGGAN ROBERT W A-Award 11,232.00 $17.52 $196,785
2026-01-02 Booth Robert F. A-Award 35,000.00 $17.52 $613,200
2026-01-02 Booth Robert F. A-Award 7,180.00 $17.52 $125,794
2026-01-02 Xia Yu A-Award 35,000.00 $17.52 $613,200
2026-01-02 Huber Jeff A-Award 35,000.00 $17.52 $613,200
2026-01-02 Huber Jeff A-Award 9,885.00 $17.52 $173,185
2026-01-02 Ronaghi Mostafa A-Award 35,000.00 $17.52 $613,200
2026-01-02 Clark Kenneth A A-Award 35,000.00 $17.52 $613,200
2026-01-02 Clark Kenneth A A-Award 17,796.00 $17.52 $311,786
2026-01-02 Cesano Alessandra A-Award 35,000.00 $17.52 $613,200
2026-01-02 Cesano Alessandra A-Award 3,219.00 $17.52 $56,397
2025-10-21 Xia Yu P-Purchase 533,617.00 $18.74 $10.0M
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for SMMT — it's generated by the pipeline (market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30