Business Description
Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with B cell-mediated autoimmune diseases. Its proprietary technology utilizes chimeric autoantibody receptor (CAAR) T cells that are designed to selectively bind and eliminate B cells, which produce disease-causing autoantibodies or pathogenic B cells. The company's lead product candidate is DSG3-CAART, which is in Phase I clinical trial for the treatment of mucosal pemphigus vulgaris, an autoimmune blistering skin disease, and Hemophilia A with Factor VIII alloantibodies. Its product candidate pipeline also includes MuSK-CAART, a preclinical stage product to treat a subset of patients with myasthenia gravis; FVIII-CAART, a discovery stage product to treat a subset of patients with Hemophilia A; and DSG3/1-CAART, a discovery stage product for the treatment of mucocutaneous pemphigus vulgaris. It has a collaboration with the University of Pennsylvania; and research agreement with The Regents of the University of California. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.
Business History
Price Overview
Last updated: May 11, 2026 1:55pm (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -1.64
Total Equity: $112.05M
Shares: 102,262,904
Total Debt: $27.10M
Cash: $82.98M
EBITDA: -$170.60M
Total Debt: $27.10M
Cash: $82.98M
Revenue: $0.00
Revenue: $0.00
Revenue: $0.00
Total Equity: $112.05M
Tax Rate: 0.0%
Equity: $112.05M
Total Debt: $27.10M
Cash: $82.98M
Current Liabilities: $50.15M
Long-Term Debt: $2.88M
Total Debt: $27.10M
Total Equity: $112.05M
Shares: 102,262,904
Shares: 102,262,904
CapEx: -$1.23M
Shares: 102,262,904
Stock Price: $3.74
Net Income: -$167.86M
Industry Benchmarks
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
Income Statement (Annual)
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 |
| Cost of Revenue | $733,000 | $3.7M | $1.4M | $4.8M | $1.6M |
| Gross Profit | $-733,000 | -$3.7M | -$1.4M | -$4.8M | -$1.6M |
| Operating Expenses | $45.6M | $50.5M | $73.2M | $120.3M | $170.6M |
| Operating Income | -$46.3M | -$54.1M | -$74.7M | -$125.1M | -$172.2M |
| Net Income | -$46.3M | -$53.0M | -$67.7M | -$115.9M | -$167.9M |
| EBITDA | -$45.6M | -$49.3M | -$66.2M | -$110.3M | -$170.6M |
| EPS | $-1.80 | $-1.81 | $-1.65 | $-2.34 | $-1.64 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $122.2M | $81.6M | $193.2M | $164.0M | $83.0M |
| Total Current Assets | $124.5M | $108.8M | $244.5M | $166.7M | $138.9M |
| Total Assets | $126.3M | $117.0M | $253.7M | $185.0M | $165.1M |
| Current Liabilities | $8.4M | $9.5M | $16.0M | $27.1M | $50.2M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $2.9M |
| Total Liabilities | $8.4M | $12.4M | $17.5M | $32.7M | $53.0M |
| Total Equity | $118.0M | $104.5M | $236.2M | $152.3M | $112.1M |
| Retained Earnings | -$112.6M | -$165.6M | -$233.2M | -$349.1M | -$517.0M |
Cash Flow (Annual)
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$34.1M | -$46.4M | -$53.5M | -$88.2M | -$131.1M |
| Capital Expenditure | -$1.2M | -$2.5M | $-687,000 | -$2.2M | -$1.2M |
| Free Cash Flow | -$35.3M | -$48.8M | -$54.2M | -$90.4M | -$132.3M |
| Acquisitions (net) | $0 | $24,764 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $20.8M | -$40.6M | $111.6M | -$29.3M | -$81.0M |
Analyst Estimates (Annual)
| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$712,586 $712,586 – $712,586
|
$62.2M $62.2M – $62.2M
|
$345.7M $345.7M – $345.7M
|
$787.6M $787.6M – $787.6M
|
| EBITDA | $0 | $0 | $0 | $0 |
| Net Income |
-$156.7M -$177.4M – -$136.0M
|
-$249.3M -$300.4M – -$73.9M
|
-$81.3M -$81.3M – -$81.3M
|
$66.1M $66.1M – $66.1M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | — | — | — |
| Gross Profit Growth | -402.6% | +61.3% | -237.5% | +65.8% |
| Operating Income Growth | -16.9% | -37.9% | -67.6% | -37.6% |
| Net Income Growth | -14.4% | -27.7% | -71.2% | -44.9% |
| EBITDA Growth | -8.2% | -34.4% | -66.5% | -54.7% |
Insider Trading (Recent)
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-03-02 | Das Arun | A-Award | 175,000.00 | $3.30 | $577,500 |
| 2026-03-02 | Gerard Michael | A-Award | 175,000.00 | $3.30 | $577,500 |
| 2026-03-02 | Binder Gwendolyn | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-03-02 | Chang David J. | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-03-02 | Nichtberger Steven | A-Award | 674,000.00 | $3.30 | $2.2M |
| 2026-03-02 | Marda Anup | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-01-21 | Chang David J. | P-Purchase | 8,800.00 | $2.26 | $19,888 |
| 2026-01-21 | Binder Gwendolyn | P-Purchase | 11,312.00 | $2.19 | $24,763 |
| 2026-01-21 | Tomasello Shawn | P-Purchase | 22,725.00 | $2.21 | $50,322 |
| 2026-01-21 | Gavel Steve | P-Purchase | 22,170.00 | $2.27 | $50,215 |
| 2026-01-21 | Bollard Catherine | P-Purchase | 4,405.00 | $2.27 | $9,982 |
| 2026-01-21 | Nichtberger Steven | P-Purchase | 45,000.00 | $2.24 | $100,778 |
| 2026-01-21 | Simon Mark | P-Purchase | 11,061.00 | $2.28 | $25,261 |
| 2026-01-21 | Gerard Michael | P-Purchase | 6,600.00 | $2.27 | $14,979 |
| 2025-10-13 | Gavel Steve | A-Award | 275,000.00 | $2.49 | $684,750 |
| 2025-10-13 | Gavel Steve | 0.00 | $0.00 | $0 | |
| 2025-06-09 | Simon Mark | A-Award | 22,000.00 | $2.37 | $52,140 |
| 2025-06-09 | Brun Scott C. | A-Award | 22,000.00 | $2.37 | $52,140 |
| 2025-06-09 | Bollard Catherine | A-Award | 22,000.00 | $2.37 | $52,140 |
| 2025-06-09 | Tomasello Shawn | A-Award | 22,000.00 | $2.37 | $52,140 |