Business Description
Cabaletta Bio, Inc. is a biotechnology firm in the clinical development stage, specializing in the invention and advancement of sophisticated engineered T cell therapies. Its core mission is to treat autoimmune diseases where B cells are implicated in producing harmful autoantibodies. The company's unique chimeric autoantibody receptor (CAAR) T cell platform is engineered to precisely target and eradicate these specific disease-causing B cells. Leading its pipeline is DSG3-CAART, which is currently in Phase I clinical trials. This candidate is being assessed for efficacy in two distinct conditions: mucosal pemphigus vulgaris, an autoimmune blistering skin disorder, and Hemophilia A in patients exhibiting Factor VIII alloantibodies. Cabaletta's broader product candidate portfolio also includes MuSK-CAART, a preclinical asset aimed at a particular subset of myasthenia gravis patients; FVIII-CAART, in the discovery phase for another subgroup of Hemophilia A sufferers; and DSG3/1-CAART, also a discovery-stage program, designed for mucocutaneous pemphigus vulgaris. The company maintains strategic alliances, including a collaboration with the University of Pennsylvania and a research pact with The Regents of the University of California. Founded in 2017 as Tycho Therapeutics, Inc., it adopted the name Cabaletta Bio, Inc. in August 2018 and is based in Philadelphia, Pennsylvania.
Business History
Price Overview
Last updated: Jun 27, 2026 9:05am (just now)Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -1.64
Total Equity: $112.05M
Shares: 102,262,904
Total Debt: $2.88M
Cash: $82.98M
EBITDA: -$164.21M
Total Debt: $2.88M
Cash: $82.98M
Revenue: $0.00
Shares: 102,262,904
Revenue: $0.00
Revenue: $0.00
Revenue: $0.00
Total Equity: $112.05M
Tax Rate: 0.0%
Equity: $112.05M
Total Debt: $2.88M
Cash: $82.98M
Current Liabilities: $50.15M
Long-Term Debt: $2.88M
Total Debt: $2.88M
Total Equity: $112.05M
Shares: 102,262,904
Shares: 102,262,904
CapEx: -$1.23M
Shares: 102,262,904
Stock Price: $3.04
Net Income: -$167.86M
Industry Benchmarks
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
Income Statement (Annual)
Last updated: Jun 26, 2026 6:28pm (14h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | $0 | $0 | $0 | $0 | $0 |
| Operating Expenses | $46.3M | $54.1M | $74.7M | $125.1M | $172.2M |
| Operating Income | -$46.3M | -$54.1M | -$74.7M | -$125.1M | -$172.2M |
| Net Income | -$46.3M | -$53.0M | -$67.7M | -$115.9M | -$167.9M |
| EBITDA | -$45.6M | -$51.8M | -$66.2M | -$113.4M | -$164.2M |
| EPS | $-1.80 | $-1.81 | $-1.65 | $-2.34 | $-1.64 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 26, 2026 6:28pm (14h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $122.2M | $81.6M | $193.2M | $164.0M | $83.0M |
| Total Current Assets | $124.5M | $108.8M | $244.5M | $166.7M | $138.9M |
| Total Assets | $126.3M | $117.0M | $253.7M | $185.0M | $165.1M |
| Current Liabilities | $8.4M | $9.5M | $16.0M | $27.1M | $50.2M |
| Long-Term Debt | $0 | $0 | $0 | $0 | $2.9M |
| Total Liabilities | $8.4M | $12.4M | $17.5M | $32.7M | $53.0M |
| Total Equity | $118.0M | $104.5M | $236.2M | $152.3M | $112.1M |
| Retained Earnings | -$112.6M | -$165.6M | -$233.2M | -$349.1M | -$517.0M |
Cash Flow (Annual)
Last updated: Jun 26, 2026 6:28pm (14h ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$34.1M | -$46.4M | -$53.5M | -$88.2M | -$131.1M |
| Capital Expenditure | -$1.2M | -$2.5M | $-687,000 | -$2.2M | -$1.2M |
| Free Cash Flow | -$35.3M | -$48.8M | -$54.2M | -$90.4M | -$132.3M |
| Acquisitions (net) | $0 | $24,764 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $20.8M | -$40.6M | $111.6M | -$29.3M | -$81.0M |
Analyst Estimates (Annual)
Last updated: Jun 26, 2026 6:28pm (14h ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$712,586 $712,586 – $712,586
|
$63.7M $63.7M – $63.7M
|
$345.7M $345.7M – $345.7M
|
$787.6M $787.6M – $787.6M
|
| EBITDA | $0 | $0 | $0 | $0 |
| Net Income |
-$126.3M -$148.4M – -$104.3M
|
-$240.2M -$248.6M – -$48.2M
|
-$66.5M -$66.5M – -$66.5M
|
$85.4M $85.4M – $85.4M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 26, 2026 6:28pm (14h ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | — | — | — | — |
| Gross Profit Growth | — | — | — | — |
| Operating Income Growth | -16.9% | -37.9% | -67.6% | -37.6% |
| Net Income Growth | -14.4% | -27.7% | -71.2% | -44.9% |
| EBITDA Growth | -13.7% | -27.9% | -71.2% | -44.8% |
Insider Trading (Recent)
Last updated: Jun 27, 2026 3:11am (5h ago)All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-09 | Tomasello Shawn | A-Award | 22,000.00 | $3.22 | $70,840 |
| 2026-06-09 | Simon Mark | A-Award | 22,000.00 | $3.22 | $70,840 |
| 2026-06-09 | HENRIQUES RICHARD C JR | A-Award | 22,000.00 | $3.22 | $70,840 |
| 2026-06-09 | Bollard Catherine | A-Award | 22,000.00 | $3.22 | $70,840 |
| 2026-06-09 | Brun Scott C. | A-Award | 22,000.00 | $3.22 | $70,840 |
| 2026-03-02 | Das Arun | A-Award | 175,000.00 | $3.30 | $577,500 |
| 2026-03-02 | Gerard Michael | A-Award | 175,000.00 | $3.30 | $577,500 |
| 2026-03-02 | Binder Gwendolyn | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-03-02 | Chang David J. | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-03-02 | Nichtberger Steven | A-Award | 674,000.00 | $3.30 | $2.2M |
| 2026-03-02 | Marda Anup | A-Award | 225,000.00 | $3.30 | $742,500 |
| 2026-01-21 | Chang David J. | P-Purchase | 8,800.00 | $2.26 | $19,888 |
| 2026-01-21 | Binder Gwendolyn | P-Purchase | 11,312.00 | $2.19 | $24,763 |
| 2026-01-21 | Tomasello Shawn | P-Purchase | 22,725.00 | $2.21 | $50,322 |
| 2026-01-21 | Gavel Steve | P-Purchase | 22,170.00 | $2.27 | $50,215 |
| 2026-01-21 | Bollard Catherine | P-Purchase | 4,405.00 | $2.27 | $9,982 |
| 2026-01-21 | Nichtberger Steven | P-Purchase | 45,000.00 | $2.24 | $100,778 |
| 2026-01-21 | Simon Mark | P-Purchase | 11,061.00 | $2.28 | $25,261 |
| 2026-01-21 | Gerard Michael | P-Purchase | 6,600.00 | $2.27 | $14,979 |
| 2025-10-13 | Gavel Steve | A-Award | 275,000.00 | $2.49 | $684,750 |
Narrative Economics
market-narrative step).