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Humacyte, Inc.

HUMA NASDAQ Categories PDF
Healthcare · Biotechnology
Durham, NC 27713, United States IPO 2020 humacyte.com Updated Jun 27, 8:02am
Price
$0.71
Market Cap
$119.0M
Employees
218
Beta
2.46
Avg Volume
8,690,448
CEO
Laura E. Niklason
Business Description

Humacyte, Inc. focuses on developing and manufacturing readily available, implantable human tissues engineered in a laboratory setting. These bioengineered tissues are designed to treat a wide array of diseases and conditions across various anatomical locations and therapeutic fields. The company employs its distinct scientific and proprietary technology platform to produce human acellular vessels (HAVs). These investigational HAVs are specifically crafted for universal compatibility, enabling easy implantation into any patient without inducing an immune rejection or an adverse foreign body response. Humacyte is currently building a pipeline of HAVs targeting the substantial market for vascular repair, reconstruction, and replacement. This includes applications such as treating vascular trauma, providing arteriovenous access for hemodialysis, addressing peripheral arterial disease, and facilitating coronary artery bypass grafting. Furthermore, the company is exploring the use of its HAVs for pediatric heart surgeries and for cellular therapeutic delivery, including the transplantation of pancreatic islet cells to manage Type 1 diabetes. Founded in 2004, Humacyte maintains its headquarters in Durham, North Carolina.

Business History
Price Overview
Last updated: Jun 27, 2026 8:02am (just now)
$0.71
+0.09 (+14.29%)
Day Range
$0.61 – $0.80
52-Week Range
$0.55 – $2.84
50-Day MA
$0.99
200-Day MA
$1.17
Volume
46,788,390.00
Analyst Price Targets
Low $3.00
Consensus $5.58
High $10.00
(7 analysts)
Share Structure
Outstanding 168,000,000.00
Float 138,120,703.00
Free Float 82.2%
High free float — 82.2% of shares trade freely, ~17.8% held by insiders/institutions
Very liquid — most shares trade freely. Low insider ownership can mean less management alignment, but makes large position sizing straightforward.
Price History (1 Year)
Last updated: Jun 27, 2026 8:02am (just now)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Last updated: Jun 24, 2026 6:29am (3d ago)
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
Period Revenue Net Income Net Margin YoY/QoQ
Key Metrics
API Direct from provider CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALC
Stock Price / EPS (Diluted)
-2.73
Stock Price: $0.71
EPS (Diluted): -0.26
P/B Ratio (Price vs net asset value)
API
Stock Price / Book Value Per Share
48.86
Stock Price: $0.71
Total Equity: $3.11M
Shares: 158,160,468
EV/EBITDA (Total value vs operating profit)
API
Enterprise Value / EBITDA
-1.71
Market Cap: $119.04M
Total Debt: $35.44M
Cash: $50.50M
EBITDA: -$22.24M
Enterprise Value (Takeover price (cap + debt - cash))
API
Market Cap + Total Debt - Cash
$166.3M
Market Cap: $119.04M
Total Debt: $35.44M
Cash: $50.50M
P/S Ratio (Price per dollar of revenue)
API
Stock Price / Revenue Per Share
74.54
Stock Price: $0.71
Revenue: $2.04M
Shares: 158,160,468
EV/Sales (Total value vs revenue — works when P/E can't)
API
81.58
Gross Margin (Revenue left after direct costs)
API
Gross Profit / Revenue
-736.5%
Gross Profit: -$15.01M
Revenue: $2.04M
Operating Margin (Revenue left after all operations)
API
Operating Income / Revenue
-5,271.7%
Operating Income: -$107.44M
Revenue: $2.04M
Net Margin (Revenue left as actual profit)
API
Net Income / Revenue
-2,003.6%
Net Income: -$40.83M
Revenue: $2.04M
ROE (Profit from shareholder equity)
API
Net Income / Total Equity
-2,781.6%
Net Income: -$40.83M
Total Equity: $3.11M
ROIC (Profit from all invested capital)
API
NOPAT / Invested Capital
-117.7%
Operating Income: -$107.44M
Tax Rate: 0.0%
Equity: $3.11M
Total Debt: $35.44M
Cash: $50.50M
Current Ratio (Can it pay short-term bills)
API
Current Assets / Current Liabilities
3.69
Current Assets: $67.80M
Current Liabilities: $18.37M
Debt/Equity (Leverage — debt vs equity)
CALC
Total Debt / Total Equity
11.40
Short-Term Debt: $0.00
Long-Term Debt: $35.44M
Total Debt: $35.44M
Total Equity: $3.11M
Rev/Share (Top-line per share)
CALC
Revenue / Shares Outstanding
$0.01
Revenue: $2.04M
Shares: 158,160,468
Book Value/Share (Net assets per share)
CALC
(Total Assets - Total Liabilities) / Shares
$0.02
Total Equity: $3.11M
Shares: 158,160,468
FCF/Share (Real cash generated per share)
CALC
(Operating Cash Flow + CapEx) / Shares
$-0.67
Operating CF: -$105.04M
CapEx: -$884,000
Shares: 158,160,468
CapEx is negative (outflow) — added to OCF to get FCF
Div Yield (Annual income from holding)
API
Last Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $0.71
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
Dividends Paid: N/A
Net Income: -$40.83M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares HUMA against LLM-researched typical ranges for its industry. One research call per industry, cached indefinitely — every stock in the same industry reuses the same baseline.
Deep Analysis

Pre-flight intelligence scans the company first, then routes to the right analytical methods.

0 Company Classification — What type of company is this?
1 Industry Landscape — Where is the industry headed?
2 Company Momentum — Where is this company trending?
3 Forward Projection — 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a DCF Valuation — Present value of future cash flows
4b Earnings Power Value — Floor value — worth with zero growth
4c Anchored PE — Industry PE adjusted for growth differential
4d Reverse DCF — What growth is the market pricing in?
4e Revenue-Based DCF — For growth/narrative companies (skip if mature earner)
4f Anchored P/S — Price-to-Sales peer comparison (skip if mature earner)
4g Scenario Analysis — Bull / Base / Bear (skip if mature earner)
4h Dividend Discount Model — For dividend/income stocks only
4i Book Value Analysis — For deep value / turnaround stocks only
4j Insider Activity — Are insiders buying or selling?
4f Cash Flow Quality — How trustworthy is the FCF?
4g Debt Maturity Risk — Can it handle its debt?
4h Macro Environment — Rates, market valuation, volatility
4i Sector Intelligence — How does this company compare within its sector?
4j Revenue Confidence — How reliable is the growth projection?
4k Sensitivity Analysis — How fragile is the fair value estimate?
4l Sector Demand Cycle — Is the sector in a boom, steady state, or contraction?
5 AI Investigation — Adaptive research engine (Claude)
5b Thesis Evaluation — What does the market believe? (narrative/platform stocks only)
6 Valuation Synthesis — Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 24, 2026 6:29am (3d ago)
Metric 2021 2022 2023 2024 2025
Revenue $1.3M $1.6M $0 $0 $2.0M
Cost of Revenue $61.3M $8.3M $76.6M $7.2M $17.0M
Gross Profit -$60.1M -$6.7M -$76.6M -$7.2M -$15.0M
Operating Expenses $21.1M $77.9M $23.5M $107.2M $92.4M
Operating Income -$81.2M -$84.6M -$100.0M -$114.4M -$107.4M
Net Income -$26.5M -$12.0M -$110.8M -$148.7M -$40.8M
EBITDA -$13.9M $2.4M -$96.5M -$132.2M -$22.2M
EPS $-0.66 $-0.12 $-1.07 $-1.26 $-0.26
EPS (Diluted)
Balance Sheet (Annual)
Last updated: Jun 24, 2026 6:29am (3d ago)
Metric 2021 2022 2023 2024 2025
Cash & Equivalents $217.5M $149.8M $80.4M $44.9M $50.5M
Total Current Assets $229.3M $154.2M $83.3M $47.9M $67.8M
Total Assets $286.5M $204.3M $128.2M $137.9M $116.4M
Current Liabilities $11.1M $19.6M $18.4M $20.0M $18.4M
Long-Term Debt $27.4M $20.3M $38.6M $63.4M $35.4M
Total Liabilities $164.4M $87.4M $114.7M $190.5M $113.3M
Total Equity $122.2M $116.9M $13.5M -$52.7M $3.1M
Retained Earnings -$414.6M -$426.5M -$537.3M -$686.0M -$726.8M
Cash Flow (Annual)
Last updated: Jun 24, 2026 6:29am (3d ago)
Metric 2021 2022 2023 2024 2025
Operating Cash Flow -$81.2M -$71.1M -$73.3M -$98.1M -$105.0M
Capital Expenditure $-220,000 -$1.0M -$2.3M -$1.6M $-884,000
Free Cash Flow -$81.4M -$72.2M -$75.6M -$99.7M -$105.9M
Acquisitions (net) $0 $0 $0 $0 $0
Debt Repayment
Dividends Paid
Stock Buybacks $0 $0 $0 $0 $0
Net Change in Cash $177.6M -$67.7M -$69.2M $14.5M -$44.4M
Analyst Estimates (Annual)
Last updated: Jun 27, 2026 8:02am (just now)
Metric 2027 2028 2029 2030
Revenue $26.3M
$16.9M – $35.7M
$119.3M
$116.1M – $122.5M
$231.9M
$140.1M – $358.0M
$342.6M
$206.9M – $528.9M
EBITDA $5.3M
$3.4M – $7.1M
$23.9M
$23.2M – $24.5M
$46.4M
$28.0M – $71.6M
$68.5M
$41.4M – $105.8M
Net Income -$38.9M
-$42.1M – -$35.7M
-$9.0M
-$22.1M – $17.4M
$15.0M
$7.3M – $25.6M
$47.4M
$23.0M – $81.0M
EPS
Growth Trends (YoY %)
Last updated: Jun 24, 2026 6:29am (3d ago)
Metric 2022 2023 2024 2025
Revenue Growth +23.9% -100.0%
Gross Profit Growth +88.9% -1,044.2% +90.6% -108.7%
Operating Income Growth -4.1% -18.3% -14.3% +6.1%
Net Income Growth +54.8% -825.8% -34.2% +72.5%
EBITDA Growth +117.6% -4,045.1% -37.1% +83.2%
Insider Trading (Recent)
Type codes PPurchase SSale AAward / grant MOption exercise FIn-kind (tax) CConversion GGift DReturn to issuer
All SEC Form 4 codes
Open market
P Purchase
Open-market or private purchase of shares.
S Sale
Open-market or private sale of shares.
Compensation (Rule 16b-3)
A Award / grant
Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
D Return to issuer
Securities disposed back to the company under Rule 16b-3.
F In-kind (tax)
Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
I Discretionary
Discretionary transaction under an employee plan — Rule 16b-3(f).
M Option exercise
Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
C Conversion
Conversion of a derivative security into the underlying shares.
E Short expiration
Expiration of a short derivative position.
H Long expiration
Expiration or cancellation of a long derivative position with value received.
O OTM exercise
Exercise of an out-of-the-money derivative.
X ITM exercise
Exercise of an in-the-money or at-the-money derivative.
Other exempt
G Gift
Bona fide gift of securities.
L Small acquisition
Small acquisition under Rule 16a-6.
W Inheritance
Acquisition or disposition by will or the laws of descent.
Z Voting trust
Deposit into or withdrawal from a voting trust.
Other
J Other
Other acquisition or disposition (explained in a Form 4 footnote).
K Equity swap
Transaction in an equity swap or similar instrument.
U Tender / buyout
Disposition via tender of shares in a change-of-control transaction.

Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.

Date Insider Type Shares Price Value
2026-06-11 Windham-Bannister Susan Richards A-Award 80,000.00 $1.08 $86,400
2026-06-11 Constantino Michael T. A-Award 80,000.00 $1.08 $86,400
2026-06-11 Wallace Max N. A-Award 80,000.00 $1.08 $86,400
2026-06-11 Niklason Laura E A-Award 80,000.00 $1.08 $86,400
2026-06-11 Sebelius Kathleen A-Award 80,000.00 $1.08 $86,400
2026-06-11 Jones Keith Anthony A-Award 80,000.00 $1.08 $86,400
2026-06-11 Green Charles Bruce A-Award 80,000.00 $1.08 $86,400
2026-06-11 Seimetz Diane A-Award 80,000.00 $1.08 $86,400
2026-06-11 Bamforth John Philip A-Award 80,000.00 $1.08 $86,400
2026-06-11 Brown Emery N. A-Award 80,000.00 $1.08 $86,400
2026-06-11 Dougan Brady W A-Award 0.00 $1.08 $0
2026-05-19 Sebelius Kathleen P-Purchase 56,818.00 $0.88 $50,000
2026-05-18 Constantino Michael T. P-Purchase 11,000.00 $0.89 $9,840
2026-05-18 Sander Dale A. S-Sale 45,887.00 $0.90 $41,147
2026-05-18 Parikh Shamik J S-Sale 45,887.00 $0.90 $41,147
2021-08-26 FRESENIUS MEDICAL CARE HOLDINGS INC /NY/ 0.00 $0.00 $0
2025-11-16 Sander Dale A. A-Award 311,100.00 $0.00 $0
2025-11-16 Parikh Shamik J A-Award 311,100.00 $0.00 $0
2025-11-16 Dougan Brady W A-Award 311,100.00 $1.23 $382,653
2025-11-16 Niklason Laura E A-Award 311,100.00 $1.23 $382,653
Narrative Economics
The story the market is telling about this stock — the intangible X-factor (founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for HUMA — it's generated by the pipeline (market-narrative step).
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.352 · d1100787 · 2026-06-26 11:39:30