Healthcare · Biotechnology
Price
$13.16
Market Cap
$17.2M
Employees
7
Beta
-0.17
Avg Volume
30,516
CEO
Neil K. Warma
Business Description
ProMIS Neurosciences, Inc. is a Canadian biotechnology firm dedicated to creating targeted therapeutic solutions for debilitating neurodegenerative conditions such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA). The company leverages a unique computational discovery platform, utilizing its ProMIS and Collective Coordinates algorithms, to identify novel, disease-specific targets – known as epitopes – located on the surface of misfolded proteins. Its pipeline features several promising drug candidates, including PMN310, a monoclonal antibody designed to address toxic oligomers implicated in Alzheimer's disease. Another candidate, PMN267, targets superoxide dismutase 1 and TAR-DNA binding protein 43 in ALS, and alpha-synuclein associated with Parkinson's disease and Lewy body dementia. Finally, PMN442 is a monoclonal antibody aimed at toxic alpha-synuclein oligomers and seeding fibrils relevant to multiple system atrophy. Established in 2004, the company changed its name from Amorfix Life Sciences Ltd. to ProMIS Neurosciences, Inc. in July 2015. Its corporate headquarters are situated in Toronto, Canada.
Business History
Price Overview
Last updated: Jun 30, 2026 9:29pm (just now)$13.16
+2.41 (+22.42%)
Day Range
$11.00 – $14.01
52-Week Range
$6.27 – $39.75
50-Day MA
$10.55
200-Day MA
$11.72
Volume
295,274.00
Analyst Price Targets
Low
$18.00
Consensus
$18.00
High
$18.00
(2 analysts)
Share Structure
Outstanding
1,307,568.00
Float
838,220.00
Free Float
64.1%
Normal free float
— 64.1% of shares trade freely, ~35.9% held by insiders/institutions
Healthy float typical of established companies. Good liquidity for entering and exiting positions without major price impact.
Small absolute float (0.8M shares) — even with a decent free float %, volume can be thin. Check average daily volume before sizing a position.
Price History (1 Year)
Revenue & Net Income Trend
The directional story — useful even when net income is negative.
Revenue
The top line — total sales before any costs or taxes are subtracted. A measure of how much business the company is doing.
Net Income
The bottom line — profit left after subtracting all expenses, interest, and taxes from revenue. Reflects accounting profitability, but includes non-cash items like depreciation, so it isn't the same as cash earned.
Operating Cash Flow
The real cash generated by the day-to-day business — selling products, paying suppliers, collecting from customers. Calculated from net income by adding back non-cash items and adjusting for timing (unpaid bills, unsold inventory). When OCF consistently lags net income, the reported profit may not be converting to real money.
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
API Direct from provider
CALC Derived from statements
P/E Ratio (Price per dollar of earnings)
CALCStock Price / EPS (Diluted)
-0.58
Stock Price: $13.16
EPS (Diluted): -22.61
EPS (Diluted): -22.61
P/B Ratio (Price vs net asset value)
APIStock Price / Book Value Per Share
-9,533.86
Stock Price: $13.16
Total Equity: -$1.26M
Shares: 1,756,844,000
Total Equity: -$1.26M
Shares: 1,756,844,000
EV/EBITDA (Total value vs operating profit)
APIEnterprise Value / EBITDA
1.14
Market Cap: $17.21M
Total Debt: $0.00
Cash: $6.12M
EBITDA: -$39.72M
Total Debt: $0.00
Cash: $6.12M
EBITDA: -$39.72M
Enterprise Value (Takeover price (cap + debt - cash))
APIMarket Cap + Total Debt - Cash
$12.0B
Market Cap: $17.21M
Total Debt: $0.00
Cash: $6.12M
Total Debt: $0.00
Cash: $6.12M
P/S Ratio (Price per dollar of revenue)
APIStock Price / Revenue Per Share
0.00
Stock Price: $13.16
Revenue: $0.00
Shares: 1,756,844,000
Revenue: $0.00
Shares: 1,756,844,000
EV/Sales (Total value vs revenue — works when P/E can't)
API0.00
Gross Margin (Revenue left after direct costs)
APIGross Profit / Revenue
0.0%
Gross Profit: $0.00
Revenue: $0.00
Revenue: $0.00
Operating Margin (Revenue left after all operations)
APIOperating Income / Revenue
0.0%
Operating Income: -$40.17M
Revenue: $0.00
Revenue: $0.00
Net Margin (Revenue left as actual profit)
APINet Income / Revenue
0.0%
Net Income: -$39.72M
Revenue: $0.00
Revenue: $0.00
ROE (Profit from shareholder equity)
APINet Income / Total Equity
-238.0%
Net Income: -$39.72M
Total Equity: -$1.26M
Total Equity: -$1.26M
ROIC (Profit from all invested capital)
APINOPAT / Invested Capital
-68.0%
Operating Income: -$40.17M
Tax Rate: 0.0%
Equity: -$1.26M
Total Debt: $0.00
Cash: $6.12M
Tax Rate: 0.0%
Equity: -$1.26M
Total Debt: $0.00
Cash: $6.12M
Zero debt — invested capital = equity minus cash (very efficient)
Current Ratio (Can it pay short-term bills)
APICurrent Assets / Current Liabilities
0.88
Current Assets: $9.18M
Current Liabilities: $10.41M
Current Liabilities: $10.41M
Debt/Equity (Leverage — debt vs equity)
CALCTotal Debt / Total Equity
0.00
Short-Term Debt: $0.00
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: -$1.26M
Long-Term Debt: $0.00
Total Debt: $0.00
Total Equity: -$1.26M
Zero debt — this company carries no debt obligations. Strongest possible score.
Rev/Share (Top-line per share)
Revenue / Shares Outstanding
—
Revenue: $0.00
Shares: 1,756,844,000
Shares: 1,756,844,000
Book Value/Share (Net assets per share)
CALC(Total Assets - Total Liabilities) / Shares
$0.00
Total Equity: -$1.26M
Shares: 1,756,844,000
Shares: 1,756,844,000
FCF/Share (Real cash generated per share)
CALC(Operating Cash Flow + CapEx) / Shares
$-0.02
Operating CF: -$28.12M
CapEx: $0.00
Shares: 1,756,844,000
CapEx: $0.00
Shares: 1,756,844,000
Div Yield (Annual income from holding)
APILast Annual Dividend / Stock Price
0.0%
Last Dividend: N/A
Stock Price: $13.16
Stock Price: $13.16
Payout Ratio (Earnings paid out as dividends)
Dividends Paid / Net Income
—
Dividends Paid: N/A
Net Income: -$39.72M
Net Income: -$39.72M
Dividends paid not available in cash flow statement
Industry Benchmarks
Compares PMN against LLM-researched typical ranges for its
industry. One research call per industry, cached indefinitely — every stock in the same industry
reuses the same baseline.
Deep Analysis
Pre-flight intelligence scans the company first, then routes to the right analytical methods.
0
Company Classification
— What type of company is this?
1
Industry Landscape
— Where is the industry headed?
2
Company Momentum
— Where is this company trending?
3
Forward Projection
— 1Y & 2Y projected metrics (requires Layer 1 + 2)
4a
DCF Valuation
— Present value of future cash flows
4b
Earnings Power Value
— Floor value — worth with zero growth
4c
Anchored PE
— Industry PE adjusted for growth differential
4d
Reverse DCF
— What growth is the market pricing in?
4e
Revenue-Based DCF
— For growth/narrative companies (skip if mature earner)
4f
Anchored P/S
— Price-to-Sales peer comparison (skip if mature earner)
4g
Scenario Analysis
— Bull / Base / Bear (skip if mature earner)
4h
Dividend Discount Model
— For dividend/income stocks only
4i
Book Value Analysis
— For deep value / turnaround stocks only
4j
Insider Activity
— Are insiders buying or selling?
4f
Cash Flow Quality
— How trustworthy is the FCF?
4g
Debt Maturity Risk
— Can it handle its debt?
4h
Macro Environment
— Rates, market valuation, volatility
4i
Sector Intelligence
— How does this company compare within its sector?
4j
Revenue Confidence
— How reliable is the growth projection?
4k
Sensitivity Analysis
— How fragile is the fair value estimate?
4l
Sector Demand Cycle
— Is the sector in a boom, steady state, or contraction?
5
AI Investigation
— Adaptive research engine (Claude)
5b
Thesis Evaluation
— What does the market believe? (narrative/platform stocks only)
6
Valuation Synthesis
— Weighted verdict from all methods (requires Layer 4)
Income Statement (Annual)
Last updated: Jun 30, 2026 9:29pm (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $8,138 | $0 | $0 | $0 | $0 |
| Cost of Revenue | $5.9M | $15,070 | $10.4M | $0 | $0 |
| Gross Profit | -$5.8M | $-15,070 | -$10.4M | $0 | $0 |
| Operating Expenses | $4.6M | $31.4M | $8.5M | $16.8M | $40.2M |
| Operating Income | -$8.2M | -$31.4M | -$18.9M | -$16.8M | -$40.2M |
| Net Income | -$12.0M | -$24.3M | -$17.5M | $2.8M | -$39.7M |
| EBITDA | -$9.3M | -$23.9M | -$17.8M | $2.9M | -$39.7M |
| EPS | $-51.77 | $-80.90 | $-35.50 | $2.75 | $-22.61 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 30, 2026 9:29pm (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $21.4M | $10.7M | $12.6M | $13.3M | $6.1M |
| Total Current Assets | $22.4M | $12.6M | $13.6M | $18.9M | $9.2M |
| Total Assets | $22.4M | $12.6M | $13.6M | $18.9M | $9.2M |
| Current Liabilities | $1.2M | $11.7M | $9.3M | $2.2M | $10.4M |
| Long-Term Debt | $4.9M | $0 | $0 | $0 | $0 |
| Total Liabilities | $15.3M | $15.0M | $9.9M | $2.4M | $10.4M |
| Total Equity | $7.2M | -$2.5M | $3.8M | $16.5M | -$1.3M |
| Retained Earnings | -$78.6M | -$146.0M | -$93.5M | -$90.7M | -$130.4M |
Cash Flow (Annual)
Last updated: Jun 30, 2026 9:29pm (just now)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$9.4M | -$22.9M | -$10.8M | -$27.2M | -$28.1M |
| Capital Expenditure | $-6,124 | $-2,661 | $0 | $0 | $0 |
| Free Cash Flow | -$9.4M | -$22.9M | -$10.8M | -$27.2M | -$28.1M |
| Acquisitions (net) | $99,702 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | $0 |
| Net Change in Cash | $16.2M | -$14.9M | $6.7M | $693,021 | -$7.2M |
Analyst Estimates (Annual)
Last updated: Jun 30, 2026 9:29pm (just now)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue | $0 |
$18.0M $18.0M – $18.0M
|
$73.5M $73.5M – $73.5M
|
$52.4M $52.4M – $52.4M
|
| EBITDA | $0 |
$10.8M $10.8M – $10.8M
|
$44.1M $44.1M – $44.1M
|
$31.5M $31.5M – $31.5M
|
| Net Income |
-$7.1B -$7.1B – -$7.1B
|
-$6.7B -$9.1B – -$4.2B
|
-$8.3B -$8.3B – -$8.3B
|
-$5.4B -$5.4B – -$5.4B
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 30, 2026 9:29pm (just now)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | -100.0% | — | — | — |
| Gross Profit Growth | +99.7% | -69,208.2% | +100.0% | — |
| Operating Income Growth | -280.8% | +39.8% | +11.0% | -138.7% |
| Net Income Growth | -102.6% | +27.9% | +115.9% | -1,529.3% |
| EBITDA Growth | -156.0% | +25.4% | +116.0% | -1,490.9% |
Insider Trading (Recent)
Type codes
PPurchase
SSale
AAward / grant
MOption exercise
FIn-kind (tax)
CConversion
GGift
DReturn to issuer
All SEC Form 4 codes
Open market
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
Compensation (Rule 16b-3)
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
Derivatives
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
Other exempt
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
Other
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-05-20 | WYMAN WILLIAM W | A-Award | 11,000.00 | $10.77 | $118,470 |
| 2026-05-20 | WYMAN WILLIAM W | A-Award | 5,500.00 | $10.77 | $59,235 |
| 2026-05-20 | Williams Eugene | A-Award | 11,000.00 | $10.77 | $118,470 |
| 2026-05-20 | Williams Eugene | A-Award | 5,500.00 | $10.77 | $59,235 |
| 2026-05-20 | Warma Neil K | A-Award | 160,000.00 | $10.77 | $1.7M |
| 2026-05-20 | Shafmaster Madge K. | A-Award | 11,000.00 | $10.77 | $118,470 |
| 2026-05-20 | Shafmaster Madge K. | A-Award | 5,500.00 | $10.77 | $59,235 |
| 2026-05-20 | Cashman Neil | A-Award | 50,000.00 | $10.77 | $538,500 |
| 2026-05-20 | Milbury Max A. | A-Award | 18,167.00 | $10.77 | $195,659 |
| 2026-05-20 | Mandel-Brehm Josh | A-Award | 11,000.00 | $10.77 | $118,470 |
| 2026-05-20 | Mandel-Brehm Josh | A-Award | 5,500.00 | $10.77 | $59,235 |
| 2026-05-20 | Kaplan Johanne | A-Award | 50,000.00 | $10.77 | $538,500 |
| 2026-05-20 | Alex Slanix Paul | A-Award | 11,000.00 | $10.77 | $118,470 |
| 2026-05-20 | Alex Slanix Paul | A-Award | 5,500.00 | $10.77 | $59,235 |
| 2026-04-22 | Kirwin Patrick D. | P-Purchase | 4,000.00 | $11.33 | $45,320 |
| 2026-03-05 | Williams Eugene | P-Purchase | 2,000.00 | $24.40 | $48,800 |
| 2026-03-04 | Williams Eugene | P-Purchase | 2,000.00 | $24.00 | $48,000 |
| 2026-03-03 | Williams Eugene | P-Purchase | 1,000.00 | $21.89 | $21,890 |
| 2026-03-02 | Williams Eugene | P-Purchase | 1,000.00 | $22.53 | $22,530 |
| 2026-02-03 | ABG V-SIV IX Ltd | 0.00 | $0.00 | $0 |
Narrative Economics
The story the market is telling about this stock — the intangible X-factor
(founder mythology, cult dynamics, TAM-of-imagination) that moves price beyond
what cash flows alone explain. After Shiller, Narrative Economics.
No narrative profile yet for PMN — it's generated by the pipeline (
market-narrative step).
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My Notes
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Data via Financial Modeling Prep · Cached for performance · fmp
v1.1.360 · 7b6df9be · 2026-06-30 17:24:24