Business Description
Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company dedicated to the discovery and advancement of genetic treatment modalities, including RNA-targeted therapeutics and gene therapies, specifically for rare diseases. The company currently offers two approved treatments: EXONDYS 51, prescribed for Duchenne muscular dystrophy (DMD) patients with confirmed dystrophin gene mutations amenable to exon 51 skipping, and VYONDYS 53, for DMD patients with exon 53 skipping mutations. Sarepta's development pipeline includes AMONDYS 45, an exon-skipping product candidate utilizing phosphorodiamidate morpholino oligomer chemistry for exon 45; SRP-5051, a peptide-conjugated PMO designed to target exon 51 of dystrophin pre-mRNA; and gene therapy programs such as SRP-9001 for DMD and SRP-9003 for limb-girdle muscular dystrophies. The company maintains collaborative agreements with organizations like F. Hoffman-La Roche Ltd, Nationwide Children's Hospital, Lysogene, Duke University, Genethon, and StrideBio. Founded in 1980, Sarepta Therapeutics is headquartered in Cambridge, Massachusetts.
Business History
Price History (1 Year)
Revenue & Net Income Trend
| Period | Revenue | Net Income | Net Margin | YoY/QoQ |
|---|
Key Metrics
EPS (Diluted): -7.13
Total Equity: $1.14B
Shares: 104,793,000
Total Debt: $828.97M
Cash: $801.28M
EBITDA: -$647.97M
Total Debt: $828.97M
Cash: $801.28M
Revenue: $2.20B
Shares: 104,793,000
Revenue: $2.20B
Revenue: $2.20B
Revenue: $2.20B
Total Equity: $1.14B
Tax Rate: -1.6%
Equity: $1.14B
Total Debt: $828.97M
Cash: $801.28M
Current Liabilities: $1.10B
Long-Term Debt: $828.97M
Total Debt: $828.97M
Total Equity: $1.14B
Shares: 104,793,000
Shares: 104,793,000
CapEx: -$101.97M
Shares: 104,793,000
Stock Price: $16.85
Net Income: -$713.41M
Industry Benchmarks
Deep Analysis
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Income Statement (Annual)
Last updated: Jun 21, 2026 7:22pm (5d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Revenue | $701.9M | $933.0M | $1.2B | $1.9B | $2.2B |
| Cost of Revenue | $97.0M | $140.0M | $150.3M | $319.1M | $881.5M |
| Gross Profit | $604.8M | $793.0M | $1.1B | $1.6B | $1.3B |
| Operating Expenses | $1.1B | $1.3B | $1.4B | $1.4B | $2.0B |
| Operating Income | -$459.7M | -$536.2M | -$267.8M | $218.1M | -$657.8M |
| Net Income | -$418.8M | -$703.5M | -$536.0M | $235.2M | -$713.4M |
| EBITDA | -$317.4M | -$594.9M | -$453.7M | $316.9M | -$648.0M |
| EPS | $-5.15 | $-8.03 | $-5.80 | $2.47 | $-7.13 |
| EPS (Diluted) | — | — | — | — | — |
Balance Sheet (Annual)
Last updated: Jun 21, 2026 7:22pm (5d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash & Equivalents | $2.1B | $966.8M | $428.4M | $1.1B | $801.3M |
| Total Current Assets | $2.6B | $2.6B | $2.6B | $3.1B | $2.5B |
| Total Assets | $3.1B | $3.1B | $3.3B | $4.0B | $3.3B |
| Current Liabilities | $452.7M | $619.6M | $653.7M | $731.7M | $1.1B |
| Long-Term Debt | $1.1B | $1.5B | $1.1B | $1.1B | $829.0M |
| Total Liabilities | $2.2B | $2.7B | $2.4B | $2.4B | $2.2B |
| Total Equity | $928.0M | $385.0M | $859.3M | $1.5B | $1.1B |
| Retained Earnings | -$3.2B | -$3.9B | -$4.4B | -$4.2B | -$4.9B |
Cash Flow (Annual)
Last updated: Jun 21, 2026 7:22pm (5d ago)| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Operating Cash Flow | -$443.2M | -$325.3M | -$501.0M | -$205.8M | -$205.5M |
| Capital Expenditure | -$38.5M | -$32.3M | -$87.3M | -$147.0M | -$102.0M |
| Free Cash Flow | -$481.7M | -$357.6M | -$588.3M | -$352.7M | -$307.5M |
| Acquisitions (net) | $0 | $0 | $0 | $0 | $0 |
| Debt Repayment | — | — | — | — | — |
| Dividends Paid | — | — | — | — | — |
| Stock Buybacks | $0 | $0 | $0 | $0 | -$25.0M |
| Net Change in Cash | $613.8M | -$1.1B | -$541.8M | $674.6M | -$304.2M |
Analyst Estimates (Annual)
Last updated: Jun 27, 2026 8:25am (37m ago)| Metric | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|
| Revenue |
$1.4B $1.3B – $1.6B
|
$1.4B $1.4B – $1.4B
|
$1.3B $1.1B – $1.6B
|
$1.3B $1.1B – $1.5B
|
| EBITDA |
-$452.8M -$517.5M – -$397.3M
|
-$442.6M -$443.2M – -$441.9M
|
-$420.0M -$493.0M – -$345.8M
|
-$407.4M -$478.1M – -$335.4M
|
| Net Income |
$91.2M $50.3M – $151.7M
|
$80.1M -$427.2M – $276.8M
|
$45.2M $34.8M – $55.4M
|
$35.8M $27.6M – $43.9M
|
| EPS | — | — | — | — |
Growth Trends (YoY %)
Last updated: Jun 21, 2026 7:22pm (5d ago)| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Revenue Growth | +32.9% | +33.3% | +53.0% | +15.6% |
| Gross Profit Growth | +31.1% | +37.8% | +44.8% | -16.8% |
| Operating Income Growth | -16.6% | +50.1% | +181.4% | -401.6% |
| Net Income Growth | -68.0% | +23.8% | +143.9% | -403.3% |
| EBITDA Growth | -87.4% | +23.7% | +169.8% | -304.5% |
Insider Trading (Recent)
Last updated: Jun 27, 2026 8:25am (37m ago)All SEC Form 4 codes
- P Purchase
- Open-market or private purchase of shares.
- S Sale
- Open-market or private sale of shares.
- A Award / grant
- Grant or award of securities (RSUs, options, etc.) under Rule 16b-3.
- D Return to issuer
- Securities disposed back to the company under Rule 16b-3.
- F In-kind (tax)
- Shares withheld or delivered to pay the option-exercise price or tax — not an open-market sale.
- I Discretionary
- Discretionary transaction under an employee plan — Rule 16b-3(f).
- M Option exercise
- Exercise or conversion of a derivative (option/RSU) into shares — exempt.
- C Conversion
- Conversion of a derivative security into the underlying shares.
- E Short expiration
- Expiration of a short derivative position.
- H Long expiration
- Expiration or cancellation of a long derivative position with value received.
- O OTM exercise
- Exercise of an out-of-the-money derivative.
- X ITM exercise
- Exercise of an in-the-money or at-the-money derivative.
- G Gift
- Bona fide gift of securities.
- L Small acquisition
- Small acquisition under Rule 16a-6.
- W Inheritance
- Acquisition or disposition by will or the laws of descent.
- Z Voting trust
- Deposit into or withdrawal from a voting trust.
- J Other
- Other acquisition or disposition (explained in a Form 4 footnote).
- K Equity swap
- Transaction in an equity swap or similar instrument.
- U Tender / buyout
- Disposition via tender of shares in a change-of-control transaction.
Compensation-plan codes (A, D, F, M) are routine and rarely directional. Open-market P (buy) and S (sale) carry the most signal.
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-06-04 | Boor Kathryn Jean | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Mayo Stephen | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Wigzell Hans Lennart Rudolf | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | BEHRENS M KATHLEEN | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Connelly Deirdre P | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Nicaise Claude | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Chambers Michael Andrew | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-06-04 | Barry Richard | A-Award | 16,875.00 | $0.00 | $0 |
| 2026-03-11 | Estepan Ian Michael | F-InKind | 1,097.00 | $17.03 | $18,682 |
| 2026-03-11 | Wong Ryan Ho-Yan | F-InKind | 256.00 | $17.03 | $4,360 |
| 2026-03-11 | Rodino-Klapac Louise | F-InKind | 948.00 | $17.03 | $16,144 |
| 2026-03-12 | Mayo Stephen | S-Sale | 7,239.00 | $17.02 | $123,208 |
| 2026-03-11 | Rothfuss Cristin | F-InKind | 974.00 | $17.03 | $16,587 |
| 2026-03-09 | Wong Ryan Ho-Yan | F-InKind | 162.00 | $16.95 | $2,746 |
| 2026-03-09 | Wong Ryan Ho-Yan | F-InKind | 113.00 | $16.95 | $1,915 |
| 2026-03-09 | Rothfuss Cristin | F-InKind | 484.00 | $16.95 | $8,204 |
| 2026-03-09 | Rothfuss Cristin | F-InKind | 346.00 | $16.95 | $5,865 |
| 2026-03-09 | Rodino-Klapac Louise | F-InKind | 504.00 | $16.95 | $8,543 |
| 2026-03-09 | Rodino-Klapac Louise | F-InKind | 895.00 | $16.95 | $15,170 |
| 2026-03-09 | Estepan Ian Michael | F-InKind | 1,036.00 | $16.95 | $17,560 |
Narrative Economics
market-narrative step).