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Daily Top 50 Gainers & Losers

cards show the S&P 500's daily move · scroll horizontally → · tracking since Apr 30, 2026

Regime: Risk-On +27 2d · nascent
Viewing Monday, Jun 22, 2026
Helper Map Key
Market Regime — the colored bar under each day is the market's overall “weather,” scored from the indexes (trend, fear/VIX, small-cap breadth). It's market-wide context, not a stock pick: even a great company gets dragged down in a red tape. Read it to gauge when to lean in vs. wait for calmer water — click any day for the full read.
Risk-On · supportive Neutral Risk-Off · headwind Stress · fear

Market Recap · Monday, June 22, 2026

Snapshot: Jun 22, 2026 · 6:00 PM 100 stocks analyzed

Up Day

Mon, Jun 22, 2026 Small-Cap Rally High

Russell 2000 surged 2.05% as small caps massively outpaced the S&P 500's 0.56% gain, with extreme dispersion and healthcare sector dominance propelling a high-conviction rotatio…

  • 60% Small-cap rally overwhelmed broad-market gains as Russell 2000 jumped 2.05% versus S&P 500's 0.56%, a 1.5-percentage-point lead that signals decisive money rotation into micro and mid-cap names. High dispersion (50+ stocks moving >25%) reinforced the stock-pickers character, with extreme winners like NXTS (+156%, AI drug partnership), GETY (+90%, OpenAI licensing), and SKYQ (+62%, refinery production milestone) anchoring the upside.
  • 25% Healthcare sector dominated the gainers list at 36% of top-50 risers, driven by clinical wins and regulatory tailwinds—DFTX surged 50% on Phase 3 depression-treatment success, ENTX +22% on FDA backing for osteoporosis trial, RGNX +16% on gene-therapy reconsideration, and NVCET +19.6% on a pipeline expansion licensing deal. The concentration underscores therapeutic optimism outweighing sector-wide caution.
  • 15% Four-day gainer streaks in CAST and HQ, plus five debutant names (APGE, FGMC, FTH, ETS, FTEK) returning to top-50 lists after absences, signal broad retail reengagement and the start of fresh momentum cycles across micro-cap territory. VIX ticked up 5.3% despite the up day, indicating underlying nervousness that contained gains to small-cap pockets rather than a broad-based rally.
Healthcare drove 36% of gainers 5 names returned after long absences CAST · 4-day gainers streak HQ · 4-day gainers streak APGE — first appearance FGMC — first appearance

Market Regime

Mon, Jun 22, 2026 Neutral conf: high macro · prototype
+11
Neutral −100 … +100 · + tailwind / − headwind
VIX17.3 p56 Drawdown-1.8% Held2d · nascent SinceJun 19
Top drivers: Small-cap leadership ▲ S&P drawdown (60d) ▲ S&P vs 50d avg ▲
processId: history-market-regime

Market Indexes

Mon, Jun 22, 2026 13
S&P 500
7,472.79
+41.33
+0.56%
Dow Jones
51,712.71
+510.45
+1.00%
NASDAQ Composite
26,166.60
+277.76
+1.07%
NASDAQ 100
30,347.08
+711.13
+2.40%
DJ US Total Market
74,119.05
+436.01
+0.59%
Russell 1000
4,065.65
+18.55
+0.46%
S&P MidCap 400
3,806.69
+10.37
+0.27%
Russell 2000
3,004.40
+60.41
+2.05%
Russell 2500
1,278.12
+9.60
+0.76%
Russell 3000
4,249.61
+22.59
+0.53%
Nasdaq Financial-100
7,178.24
−18.87
-0.26%
NIFTY 50
24,102.90
+113.75
+0.47%
VIX
17.28
+0.87
+5.30%

Biggest Gainers

Mon, Jun 22, 2026 50
NITO
N2OFF, Inc.Basic Materials
$13.12+$8.04
+158.3%
NXTS
N2OFF, Inc.Basic Materials
$13.00+$7.92
+155.9%
EHGO
Eshallgo Inc. Class A Ordinary SharesIndustrials
$4.06+$2.26
+125.6%
GETY
Getty Images Holdings, Inc.Communication Services
$1.15+$0.54
+90.1%
TNON
Tenon Medical, Inc.Healthcare
$0.62+$0.27
+77.6%
SKYQ
Sky Quarry Inc.Energy
$1.90+$0.73
+62.4%
DFTX
Mind Medicine (MindMed) Inc.Healthcare
$36.67+$12.19
+49.8%
CDT
CDT Equity Inc.Healthcare
$1.50+$0.48
+47.1%
APGE
Apogee Therapeutics, Inc.Healthcare
$132.55+$42.17
+46.7%
FGMC
FG Merger Corp.Financial Services
$14.89+$4.59
+44.6%
WYHG
Wing Yip Food Holdings Group Limited American Depositary SharesConsumer Defensive
$6.59+$1.70
+34.8%
AZTR
Azitra, Inc.Healthcare
$0.23+$0.06
+34.0%
SAGT
SAGTEC GLOBAL LtdTechnology
$1.31+$0.32
+32.3%
SMCX
Daily Target 2X Long SMCI ETFFinancial Services
$13.35+$3.17
+31.1%
APLM
Apollomics, Inc.Healthcare
$22.83+$5.33
+30.5%
FTH
Faeth Therapeutics, Inc.Healthcare
$23.19+$5.37
+30.1%
ETS
Elite Express Holding Inc.Industrials
$0.71+$0.17
+30.1%
FSHPR
Flag Ship Acquisition Corporation
$0.11+$0.02
+29.6%
FTEK
Fuel Tech, Inc.Industrials
$1.99+$0.45
+29.2%
CRMT
America's Car-Mart, Inc.Consumer Cyclical
$3.01+$0.61
+25.4%
JYD
Jayud Global Logistics LimitedIndustrials
$0.83+$0.16
+23.4%
ENTX
Entera Bio Ltd.Healthcare
$1.48+$0.27
+22.3%
DTSQR
DT Cloud Star Acquisition Corporation
$0.11+$0.02
+22.1%
CAST
FreeCast, Inc. Class A Common StockCommunication Services
$9.84+$1.77
+21.9%
STG
Sunlands Technology GroupConsumer Defensive
$4.15+$0.74
+21.7%
CANG
Cango Inc.Financial Services
$0.23+$0.04
+21.6%
RTB
RTB Digital IncTechnology
$12.46+$2.21
+21.6%
NIXX
Nixxy, Inc.Communication Services
$1.42+$0.25
+21.4%
RFIL
RF Industries, Ltd.Industrials
$21.50+$3.69
+20.7%
HQ
Horizon Quantum Holdings Ltd. Class A Ordinary SharesTechnology
$38.39+$6.39
+20.0%
NVCT
Nuvectis Pharma, Inc.Healthcare
$16.53+$2.71
+19.6%
CENN
Cenntro Electric Group LimitedConsumer Cyclical
$3.95+$0.64
+19.3%
SSTK
Shutterstock, Inc.Communication Services
$15.71+$2.49
+18.8%
SMHI
SEACOR Marine Holdings Inc.Industrials
$7.93+$1.25
+18.7%
ORIS
ORIENTAL RISE HOLDINGS LtdConsumer Defensive
$2.42+$0.38
+18.6%
XCUR
Exicure, Inc.Healthcare
$2.74+$0.43
+18.6%
ORKA
Oruka Therapeutics, Inc.Healthcare
$85.38+$13.04
+18.0%
SAFX
XCF Global, Inc. Class A Common StockUtilities
$0.49+$0.07
+17.8%
VHUB
VenHub Global, Inc. Common StockConsumer Defensive
$1.35+$0.20
+17.4%
INCR
InterCure Ltd.Healthcare
$1.09+$0.16
+17.4%
MGRT
Mega Fortune Company LimitedTechnology
$83.93+$11.98
+16.7%
ATON
AlphaTON Capital Corp.Healthcare
$0.29+$0.04
+16.6%
WYFI
WhiteFiber, Inc. Ordinary SharesTechnology
$44.77+$6.28
+16.3%
RGNX
REGENXBIO Inc.Healthcare
$9.07+$1.27
+16.3%
BWIN
The Baldwin Insurance Group, Inc.Financial Services
$23.52+$3.28
+16.2%
AVTX
Avalo Therapeutics, Inc.Healthcare
$17.08+$2.38
+16.2%
JAGX
Jaguar Health, Inc.Healthcare
$2.61+$0.36
+16.0%
CGTX
Cognition Therapeutics, Inc.Healthcare
$1.68+$0.23
+15.9%
OTLK
Outlook Therapeutics, Inc.Healthcare
$1.83+$0.25
+15.8%
FRGT
Freight Technologies, Inc.Technology
$4.41+$0.60
+15.7%

Biggest Losers

Mon, Jun 22, 2026 50
AIXI
Xiao-I CorporationTechnology
$3.06−$3.20
-51.1%
LICN
Lichen International LimitedIndustrials
$1.21−$0.96
-44.2%
SDOT
Sadot Group Inc.Consumer Defensive
$9.25−$6.93
-42.8%
SNBR
Sleep Number CorporationConsumer Cyclical
$0.13−$0.08
-39.7%
JLHL
Julong Holding Limited Class A Ordinary SharesIndustrials
$26.45−$13.24
-33.4%
LOFF
Direxion Daily SpaceX Bull 2X ETF
$21.31−$10.48
-33.0%
SPAX
T-REX 2X Long SpaceX Daily Target ETFFinancial Services
$12.85−$6.25
-32.7%
SPCF
Proshares Ultra Spacex
$21.36−$10.26
-32.4%
SMCZ
Daily Target 2X Short SMCI ETF
$6.45−$2.97
-31.5%
INLF
INLIF LimitedIndustrials
$0.11−$0.05
-29.1%
AEMD
Aethlon Medical, Inc.Healthcare
$1.38−$0.51
-27.0%
GAUZ
Gauzy Ltd. Ordinary SharesTechnology
$0.48−$0.16
-24.9%
HSPT
Horizon Space Acquisition II Corp.Financial Services
$4.48−$1.31
-22.6%
ODVWZ
Osisko Development Corp. Warrant expiring 5/27/2027Basic Materials
$0.07−$0.02
-22.2%
AHMA
Ambitions Enterprise Management Co. L.L.CConsumer Cyclical
$1.85−$0.52
-21.9%
SLBT
Horizon Space Acquisition II Corp.Healthcare
$4.52−$1.27
-21.9%
BTQ
BTQ Technologies Corp. Common StockTechnology
$4.44−$1.24
-21.8%
FAMI
Farmmi, Inc.Consumer Defensive
$1.06−$0.29
-21.5%
AVXX
Defiance Daily Target 2X Long AVAV ETF
$5.96−$1.61
-21.3%
GPUS
Hyperscale Data, Inc.Industrials
$0.29−$0.07
-20.3%
SOWG
Sow Good Inc.Consumer Defensive
$3.09−$0.78
-20.2%
ATLN
Atlantic International Corp.Industrials
$0.44−$0.11
-20.1%
VVOS
Vivos Therapeutics, Inc.Healthcare
$0.40−$0.10
-19.6%
VELO
Velo3D, Inc.Technology
$24.31−$5.55
-18.6%
AMPGR
Amplitech Group, Inc. Series A Right
$3.25−$0.74
-18.5%
BFLY
Butterfly Network, Inc.Healthcare
$7.27−$1.63
-18.3%
TRGSR
TRG Latin America Acquisitions Corp. Rights
$0.18−$0.04
-18.2%
ASTC
Astrotech CorporationTechnology
$11.27−$2.38
-17.4%
AKAN
Akanda Corp.Healthcare
$15.07−$3.13
-17.2%
PCLA
PicoCELA Inc.Communication Services
$4.00−$0.81
-16.8%
RVNL
GraniteShares 2x Long RIVN Daily ETF
$25.60−$5.17
-16.8%
CGTL
Creative Global Technology Holdings Limited Ordinary SharesConsumer Cyclical
$0.34−$0.07
-16.7%
SPCX
Space Exploration Technologies Corp.Industrials
$154.60−$30.40
-16.4%
GELS
Gelteq Limited Ordinary SharesHealthcare
$0.87−$0.17
-16.3%
CREG
Smart Powerr Corp.Utilities
$2.32−$0.45
-16.2%
YI
111, Inc.Healthcare
$3.70−$0.71
-16.1%
MODD
Modular Medical, Inc.Healthcare
$4.34−$0.81
-15.7%
NAMI
Jinxin Technology Holding Company American Depositary SharesCommunication Services
$0.21−$0.04
-15.7%
OPTH
Optimi Health Corp.Healthcare
$4.24−$0.79
-15.6%
HUBC
HUB Cyber Security Ltd.Technology
$1.68−$0.31
-15.6%
ENRD
Einride AB American Depositary SharesTechnology
$7.11−$1.31
-15.5%
MNTS
Momentus Inc.Industrials
$8.76−$1.59
-15.4%
GRAN
Grande Group Limited Class A Ordinary SharesFinancial Services
$1.34−$0.24
-15.2%
SGC
Superior Group of Companies, Inc.Consumer Cyclical
$11.63−$2.08
-15.2%
CCTG
CCSC Technology International Holdings Limited Ordinary SharesIndustrials
$0.80−$0.14
-15.0%
ANGH
Anghami Inc.Communication Services
$4.84−$0.85
-14.9%
NEOV
NeoVolta Inc.Industrials
$2.37−$0.41
-14.7%
FISN
Deep Fission, Inc. Common StockIndustrials
$12.42−$2.14
-14.7%
ARMG
Leverage Shares 2x Long ARM Daily ETF
$53.45−$9.04
-14.5%
RCAX
Daily Target 2X Long RCAT ETF
$6.25−$1.05
-14.4%